Obesity, abdominal obesity and subsequent risk of kidney cancer: a cohort study of 23.3 million East Asians

por Nam, Ga Eun, Cho, Kyung Hwan, Han, Kyungdo, Kim, Chul Min, Han, Byoungduck, Cho, Sung Jung, Jung, Seung Jin, Kwon, Yeongkeun, Kim, Yang Hyun, Kim, Do Hoon, Kim, Seon Mee, Choi, Youn Seon, Roh, Yong Kyun, Park, Yong Gyu
Publicado 2019

Negative plasma Epstein-Barr virus DNA nasopharyngeal carcinoma in an endemic region and its influence on liquid biopsy screening programmes

por Nicholls, John Malcolm, Lee, Victor Ho-Fun, Chan, Sik-Kwan, Tsang, Ka-Chun, Choi, Cheuk-Wai, Kwong, Dora Lai-Wan, Lam, Ka-On, Chan, Sum-Yin, Tong, Chi-Chung, So, Tsz-Him, Leung, To-Wai, Luk, Mai-Yee, Khong, Pek-Lan, Lee, Anne Wing-Mui
Publicado 2019

Multicenter, randomised, open-label, non-comparative phase 2 trial on the efficacy and safety of the combination of bevacizumab and trabectedin with or without carboplatin in women...

por Colombo, Nicoletta, Zaccarelli, Eleonora, Baldoni, Alessandra, Frezzini, Simona, Scambia, Giovanni, Palluzzi, Eleonora, Tognon, Germana, Lissoni, Andrea A., Rubino, Daniela, Ferrero, Annamaria, Farina, Gabriella, Negri, Emanuele, Pesenti Gritti, Angela, Galli, Francesca, Biagioli, Elena, Rulli, Eliana, Poli, Davide, Gerardi, Chiara, Torri, Valter, Fossati, Roldano, D‘Incalci, Maurizio
Publicado 2019

Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome

por Dashti, S. Ghazaleh, Li, Wing Yan, Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Winship, Ingrid M., Macrae, Finlay A., Giles, Graham G., Hardikar, Sheetal, Hua, Xinwei, Thibodeau, Stephen N., Figueiredo, Jane C., Casey, Graham, Haile, Robert W., Gallinger, Steven, Le Marchand, Loïc, Newcomb, Polly A., Potter, John D., Lindor, Noralane M., Hopper, John L., Jenkins, Mark A., Win, Aung Ko
Publicado 2019

Long-term survival in patients with metastatic head and neck squamous cell carcinoma treated with metastasis-directed therapy

por Beckham, Thomas H., Leeman, Jonathan E., Xie, Peng, Li, Xiaolin, Goldman, Debra A., Zhang, Zhigang, Sherman, Eric, McBride, Sean, Riaz, Nadeem, Lee, Nancy, Tsai, C. Jillian
Publicado 2019

p53 nuclear accumulation as an early indicator of lethal prostate cancer

por Quinn, David I., Stricker, Phillip D., Kench, James G., Grogan, Judith, Haynes, Anne-Maree, Henshall, Susan M., Grygiel, John J., Delprado, Warick, Turner, Jennifer J., Horvath, Lisa G., Mahon, Kate L.
Publicado 2019

In silico chemical screening identifies epidermal growth factor receptor as a therapeutic target of drug-tolerant CD44v9-positive gastric cancer cells

por Mashima, Tetsuo, Iwasaki, Risa, Kawata, Naomi, Kawakami, Ryuhei, Kumagai, Koshi, Migita, Toshiro, Sano, Takeshi, Yamaguchi, Kensei, Seimiya, Hiroyuki
Publicado 2019

Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer

por Joseph, Chitra, Al-Izzi, Sara, Alsaleem, Mansour, Kurozumi, Sasagu, Toss, Michael S, Arshad, Maariya, Goh, Fang Qin, Alshankyty, Ibraheem M., Aleskandarany, Mohammed A., Ali, Simak, Ellis, Ian O., Mongan, Nigel P., Green, Andrew R., Rakha, Emad A.
Publicado 2019

Treatment patterns and survival in HER2-positive early breast cancer: a whole-of-population Australian cohort study (2007–2016)

por Tang, Monica, Schaffer, Andrea, Kiely, Belinda E., Daniels, Benjamin, Simes, Robert J., Lee, Chee K., Pearson, Sallie-Anne
Publicado 2019

Apatinib in patients with extensive-stage small-cell lung cancer after second-line or third-line chemotherapy: a phase II, single-arm, multicentre, prospective study

por Xu, Yanjun, Huang, Zhiyu, Lu, Hongyang, Yu, Xinming, Li, Yuping, Li, Wenfeng, Chen, Jun, Chen, Ming, Gong, Lei, Chen, Kaiyan, Qin, Jin, Xu, Xiaoling, Jin, Ying, Zhao, Jun, Shi, Xun, Han, Na, Xie, Fajun, Zhang, Peng, Xu, Weizhen, Fan, Yun
Publicado 2019

Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial

por Witzel, Isabell, Loibl, Sibylle, Wirtz, Ralph, Fasching, Peter A., Denkert, Carsten, Weber, Karsten, Lück, Hans-Joachim, Huober, Jens, Karn, Thomas, Mackelenbergh, Marion von, Marmé, Frederik, Schem, Christian, Stickeler, Elmar, Untch, Michael, Müller, Volkmar
Publicado 2019

Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer

por Ansari, Rokaya El, Craze, Madeleine L., Althobiti, Maryam, Alfarsi, Lutfi, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Publicado 2019

Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer

por Park, Wungki, Mezquita, Laura, Okabe, Naoyuki, Chae, Young Kwang, Kwon, Deukwoo, Saravia, Diana, Auclin, Edouard, Planchard, David, Caramella, Caroline, Ferrara, Roberto, Agte, Sarita, Oh, Michael, Mudad, Raja, Jahanzeb, Mohammad, Suzuki, Hiroyuki, Besse, Benjamin, Lopes, Gilberto
Publicado 2019

Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours

por Huang, Mengyuan, Yang, Wenyu, Zhu, Jiaqing, Mariño-Enríquez, Adrián, Zhu, Chennianci, Chen, Jiaming, Wu, Yuehong, Quan, Yanping, Qiu, Haibo, Li, Xuhui, Chai, Li, Fletcher, Jonathan A., Ou, Wen-Bin
Publicado 2019

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer

por Annett, Stephanie, Moore, Gillian, Short, Amy, Marshall, Andrea, McCrudden, Cian, Yakkundi, Anita, Das, Sudipto, McCluggage, W. Glenn, Nelson, Laura, Harley, Ian, Moustafa, Nermeen, Kennedy, Catherine J., deFazio, Anna, Brand, Alison, Sharma, Raghwa, Brennan, Donal, O’Toole, Sharon, O’Leary, John, Bates, Mark, O’Riain, Ciarán, O’Connor, Darran, Furlong, Fiona, McCarthy, Helen, Kissenpfennig, Adrien, McClements, Lana, Robson, Tracy
Publicado 2019

The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma

por Rehwald, Claudia, Schnetz, Matthias, Urbschat, Anja, Mertens, Christina, Meier, Julia K., Bauer, Rebekka, Baer, Patrick, Winslow, Sofia, Roos, Frederik C., Zwicker, Klaus, Huard, Arnaud, Weigert, Andreas, Brüne, Bernhard, Jung, Michaela
Publicado 2019

Effective delivery of Complex Innovative Design (CID) cancer trials—A consensus statement

por Blagden, Sarah P., Billingham, Lucinda, Brown, Louise C., Buckland, Sean W., Cooper, Alison M., Ellis, Stephanie, Fisher, Wendy, Hughes, Helen, Keatley, Debbie A., Maignen, Francois M., Morozov, Alex, Navaie, Will, Pearson, Sarah, Shaaban, Abeer, Wydenbach, Kirsty, Kearns, Pamela R.
Publicado 2020

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma

por De Jesus-Acosta, Ana, Sugar, Elizabeth A., O’Dwyer, Peter J., Ramanathan, Ramesh K., Von Hoff, Daniel D., Rasheed, Zeshaan, Zheng, Lei, Begum, Asma, Anders, Robert, Maitra, Anirban, McAllister, Florencia, Rajeshkumar, N. V., Yabuuchi, Shinichi, de Wilde, Roeland F., Batukbhai, Bhavina, Sahin, Ismet, Laheru, Daniel A.
Publicado 2019

High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint...

por Kawashima, Masahiro, Tokiwa, Mariko, Nishimura, Tomomi, Kawata, Yukiko, Sugimoto, Masahiro, Kataoka, Tatsuki R., Sakurai, Takaki, Iwaisako, Keiko, Suzuki, Eiji, Hagiwara, Masatoshi, Harris, Adrian L., Toi, Masakazu
Publicado 2019

Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively

por Sola-Penna, Mauro, Paixão, Larissa P., Branco, Jessica R., Ochioni, Alan C., Albanese, Jamille M., Mundim, Davi M., Baptista-de-Souza, Daniela, Figueiredo, Claudia P., Coelho, Wagner S., Marcondes, Mariah C., Zancan, Patricia
Publicado 2019