Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies

por Ice, Ryan J., Chen, Michelle, Sidorov, Max, Le Ho, Tam, Woo, Rinette W. L., Rodriguez-Brotons, Aida, Luu, Tri, Jian, Damon, Kim, Kevin B., Leong, Stanley P., Kim, HanKyul, Kim, Angela, Stone, Des, Nazarian, Ari, Oh, Alyssia, Tranah, Gregory J., Nosrati, Mehdi, de Semir, David, Dar, Altaf A., Chang, Stephen, Desprez, Pierre-Yves, Kashani-Sabet, Mohammed, Soroceanu, Liliana, McAllister, Sean D.
Publicado 2019

TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours

por Saito, Yurina, Takahashi, Tsuyoshi, Obata, Yuuki, Nishida, Toshirou, Ohkubo, Shuichi, Nakagawa, Fumio, Serada, Satoshi, Fujimoto, Minoru, Ohkawara, Tomoharu, Nishigaki, Takahiko, Sugase, Takahito, Koh, Masahiro, Ishida, Tomo, Tanaka, Koji, Miyazaki, Yasuhiro, Makino, Tomoki, Kurokawa, Yukinori, Nakajima, Kiyokazu, Yamasaki, Makoto, Hirota, Seiichi, Naka, Tetsuji, Mori, Masaki, Doki, Yuichiro
Publicado 2019

A phase 2 study of intraperitoneal carboplatin plus intravenous dose-dense paclitaxel in front-line treatment of suboptimal residual ovarian cancer

por Hasegawa, Kosei, Shimada, Muneaki, Takeuchi, Satoshi, Fujiwara, Hiroyuki, Imai, Yuichi, Iwasa, Norihiro, Wada, Satoru, Eguchi, Hidetaka, Oishi, Tetsuro, Sugiyama, Toru, Suzuki, Mitsuaki, Nishiyama, Masahiko, Fujiwara, Keiichi
Publicado 2020

Temporal improvements in loco-regional failure and survival in patients with anal cancer treated with chemo-radiotherapy: treatment cohort study (1990–2014)

por Sekhar, Hema, Malcomson, Lee, Kochhar, Rohit, Sperrin, Matthew, Alam, Nooreen, Chakrbarty, Bipasha, Fulford, Paul E., Wilson, Malcolm S., O’Dwyer, Sarah T., Saunders, Mark P., Renehan, Andrew G.
Publicado 2020

Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression

por Lévesque, Eric, Labriet, Adrien, Hovington, Hélène, Allain, Éric P., Melo-Garcia, Luciana, Rouleau, Michèle, Brisson, Hervé, Turcotte, Véronique, Caron, Patrick, Villeneuve, Lyne, Leclercq, Mickaël, Droit, Arnaud, Audet-Walsh, Etienne, Simonyan, David, Fradet, Yves, Lacombe, Louis, Guillemette, Chantal
Publicado 2020

miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells

por Morimoto, Yoshihiro, Mizushima, Tsunekazu, Wu, Xin, Okuzaki, Daisuke, Yokoyama, Yuhki, Inoue, Akira, Hata, Tsuyoshi, Hirose, Haruka, Qian, Yamin, Wang, Jiaqi, Miyoshi, Norikatsu, Takahashi, Hidekazu, Haraguchi, Naotsugu, Matsuda, Chu, Doki, Yuichiro, Mori, Masaki, Yamamoto, Hirofumi
Publicado 2020

A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965

por McNeillis, Rosie, Greystoke, Alastair, Walton, Jon, Bacon, Chris, Keun, Hector, Siskos, Alexandros, Petrides, George, Leech, Nicola, Jenkinson, Fiona, Bowron, Ann, Halford, Sarah, Plummer, Ruth
Publicado 2020

Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration

por Giatromanolaki, Alexandra, Harris, Adrian L., Banham, Alison H., Contrafouris, Constantinos A., Koukourakis, Michael I.
Publicado 2020

Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials

por Hanson, Sarah, Thorpe, Gabrielle, Winstanley, Lauren, Abdelhamid, Asmaa S., Hooper, Lee
Publicado 2020

Non-inferiority randomised phase 3 trial comparing two radiation schedules (single vs. five fractions) in malignant spinal cord compression

por Thirion, Pierre G., Dunne, Mary T., Kelly, Paul J., Flavin, Aileen, O’Sullivan, Joe M., Hacking, Dayle, Sasiadek, Wojciech, Small, Cormac, Pomeroy, Maeve M., Martin, Joseph, McArdle, Orla, Parker, Imelda, O’Sullivan, Lydia S., Shannon, Aoife M., Clayton-Lea, Angela, Collins, Conor D., Stevenson, Michael R., Alvarez-Iglesias, Alberto, Armstrong, John G., Moriarty, Michael
Publicado 2020

Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials

por Vijayvergia, Namrata, Dasari, Arvind, Deng, Mengying, Litwin, Samuel, Al-Toubah, Taymeyah, Alpaugh, R. Katherine, Dotan, Efrat, Hall, Michael J., Ross, Nicole M., Runyen, Melissa M., Denlinger, Crystal S., Halperin, Daniel M., Cohen, Steven J., Engstrom, Paul F., Strosberg, Jonathan R.
Publicado 2020

An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer

por Haruki, Koichiro, Kosumi, Keisuke, Li, Peilong, Arima, Kota, Väyrynen, Juha P., Lau, Mai Chan, Twombly, Tyler S., Hamada, Tsuyoshi, Glickman, Jonathan N., Fujiyoshi, Kenji, Chen, Yang, Du, Chunxia, Guo, Chunguang, Väyrynen, Sara A., Dias Costa, Andressa, Song, Mingyang, Chan, Andrew T., Meyerhardt, Jeffrey A., Nishihara, Reiko, Fuchs, Charles S., Liu, Li, Zhang, Xuehong, Wu, Kana, Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Publicado 2020

Associations of accelerometer-measured physical activity and physical activity-related cancer incidence in older women: results from the WHI OPACH Study

por Parada, Humberto, McDonald, Emily, Bellettiere, John, Evenson, Kelly R., LaMonte, Michael J., LaCroix, Andrea Z.
Publicado 2020

Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer

por Nishigaki, Takahiko, Takahashi, Tsuyoshi, Serada, Satoshi, Fujimoto, Minoru, Ohkawara, Tomoharu, Hara, Hisashi, Sugase, Takahito, Otsuru, Toru, Saito, Yurina, Tsujii, Shigehiro, Nomura, Taisei, Tanaka, Koji, Miyazaki, Yasuhiro, Makino, Tomoki, Kurokawa, Yukinori, Nakajima, Kiyokazu, Eguchi, Hidetoshi, Yamasaki, Makoto, Mori, Masaki, Doki, Yuichiro, Naka, Tetsuji
Publicado 2020

Prognostic and clinical impact of PD-L2 and PD-L1 expression in a cohort of 437 oesophageal cancers

por Okadome, Kazuo, Baba, Yoshifumi, Nomoto, Daichi, Yagi, Taisuke, Kalikawe, Rebecca, Harada, Kazuto, Hiyoshi, Yukiharu, Nagai, Yohei, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Iwagami, Shiro, Miyamoto, Yuji, Yoshida, Naoya, Watanabe, Masayuki, Komohara, Yoshihiro, Shono, Takashi, Sasaki, Yutaka, Baba, Hideo
Publicado 2020

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody

por Ohmura, Hirofumi, Yamaguchi, Kyoko, Hanamura, Fumiyasu, Ito, Mamoru, Makiyama, Akitaka, Uchino, Keita, Shimokawa, Hozumi, Tamura, Shingo, Esaki, Taito, Mitsugi, Kenji, Shibata, Yoshihiro, Oda, Hisanobu, Tsuchihashi, Kenji, Ariyama, Hiroshi, Kusaba, Hitoshi, Oda, Yoshinao, Akashi, Koichi, Baba, Eishi
Publicado 2020

Dose-dense adjuvant chemotherapy in early breast cancer patients: 15-year results of the Phase 3 Mammella InterGruppo (MIG)-1 study

por Blondeaux, Eva, Lambertini, Matteo, Michelotti, Andrea, Conte, Benedetta, Benasso, Marco, Dellepiane, Chiara, Bighin, Claudia, Pastorino, Simona, Levaggi, Alessia, Alonzo, Alessia D’, Poggio, Francesca, Buzzatti, Giulia, Molinelli, Chiara, Fregatti, Piero, Bertoglio, Sergio, Boccardo, Francesco, Del Mastro, Lucia
Publicado 2020

LncRNA-HNF1A-AS1 functions as a competing endogenous RNA to activate PI3K/AKT signalling pathway by sponging miR-30b-3p in gastric cancer

por Liu, Hai-Ting, Ma, Ran-Ran, Lv, Bei-Bei, Zhang, Hui, Shi, Duan-Bo, Guo, Xiang-Yu, Zhang, Guo-Hao, Gao, Peng
Publicado 2020

Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study

por Mukai, Hirofumi, Yamaguchi, Takeshi, Takahashi, Masato, Hozumi, Yasuo, Fujisawa, Tomomi, Ohsumi, Shozo, Akabane, Hiromitsu, Nishimura, Reiki, Takashima, Tsutomu, Park, Youngjin, Sagara, Yasuaki, Toyama, Tatsuya, Imoto, Shigeru, Mizuno, Toshiro, Yamashita, Satoshi, Fujii, Satoshi, Uemura, Yukari
Publicado 2020

Translation and Validation of the Breast Cancer Awareness Measurement Tool in Malaysia (B-CAM-M)

por Htay, Mila Nu Nu, Donnelly, Michael, Schliemann, Desiree, Loh, Siew Yim, Dahlui, Maznah, Tamin, Nor Saleha Binti Ibrahim, Somasundaram, Saunthari, Su, Tin Tin
Publicado 2020