Bisphosphonates and risk of cancers: a systematic review and meta-analysis

por Li, Yuan-Yuan, Gao, Li-Jie, Zhang, Yu-Xue, Liu, Shu-Juan, Cheng, Shuo, Liu, Yu-Peng, Jia, Cun-Xian
Publicado 2020

Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08

por Masuishi, Toshiki, Tsuji, Akihito, Kotaka, Masahito, Nakamura, Masato, Kochi, Mitsugu, Takagane, Akinori, Shimada, Ken, Denda, Tadamichi, Segawa, Yoshihiko, Tanioka, Hiroaki, Hara, Hiroki, Sagawa, Tamotsu, Watanabe, Takanori, Takahashi, Takao, Negoro, Yuji, Manaka, Dai, Fujita, Hideto, Suto, Takeshi, Takeuchi, Masahiro, Ichikawa, Wataru, Fujii, Masashi
Publicado 2020

Vascular aging in long-term survivors of testicular cancer more than 20 years after treatment with cisplatin-based chemotherapy

por Stelwagen, Johannes, Lubberts, Sjoukje, Steggink, Lars C., Steursma, Gerrie, Kruyt, Lara M., Donkerbroek, Jan Willem, van Roon, Arie M., van Gessel, Anne I., van de Zande, Saskia C., Meijer, Coby, Gräfin zu Eulenburg, Christine H., Oosting, Sjoukje F., Nuver, Janine, Walenkamp, Annemiek M. E., Jan de Jong, Igle, Lefrandt, Joop D., Gietema, Jourik A.
Publicado 2020

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1

por Kalaw, Emarene, Lim, Malcolm, Kutasovic, Jamie R., Sokolova, Anna, Taege, Lucinda, Johnstone, Kate, Bennett, James, Saunus, Jodi M., Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Bettington, Mark, Pathmanathan, Nirmala, Tse, Gary M., Papadimos, David, Pathmanathan, Rajadurai, Harris, Gavin, Yamaguchi, Rin, Tan, Puay Hoon, Fox, Stephen, O’Toole, Sandra A., Simpson, Peter T., Lakhani, Sunil R., McCart Reed, Amy E.
Publicado 2020

Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer

por Junttila, Anna, Helminen, Olli, Väyrynen, Juha P., Ahtiainen, Maarit, Kenessey, Istvan, Jalkanen, Sirpa, Mecklin, Jukka-Pekka, Kellokumpu, Ilmo, Kuopio, Teijo, Böhm, Jan, Mrena, Johanna
Publicado 2020

Relationship of leukaemias with long-term ambient air pollution exposures in the adult Danish population

por Puett, Robin C., Poulsen, Aslak Harbo, Taj, Tahir, Ketzel, Matthias, Geels, Camilla, Brandt, Jørgen, Christensen, Jesper H., Sørensen, Mette, Roswall, Nina, Hvidtfeldt, Ulla, Raaschou-Nielsen, Ole
Publicado 2020

CB11, a novel purine-based PPARɣ ligand, overcomes radio-resistance by regulating ATM signalling and EMT in human non-small-cell lung cancer cells

por Kim, Tae Woo, Hong, Da-Won, Park, Joung Whan, Hong, Sung Hee
Publicado 2020

Treatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO

por Rossini, Daniele, Lonardi, Sara, Antoniotti, Carlotta, Santini, Daniele, Tomasello, Gianluca, Ermacora, Paola, Germani, Marco Maria, Bergamo, Francesca, Ricci, Vincenzo, Caponnetto, Salvatore, Moretto, Roberto, Zaniboni, Alberto, Pietrantonio, Filippo, Buonadonna, Angela, Ritorto, Giuliana, Masi, Gianluca, Latiano, Tiziana Pia, Rapisardi, Stefania, Falcone, Alfredo, Cremolini, Chiara
Publicado 2020

Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer

por Dwyer, Amy R., Truong, Thu H., Kerkvliet, Carlos Perez, Paul, Kiran V., Kabos, Peter, Sartorius, Carol A., Lange, Carol A.
Publicado 2020

Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis

por Bhave, Prachi, Pallan, Lalit, Long, Georgina V., Menzies, Alexander M., Atkinson, Victoria, Cohen, Justine V., Sullivan, Ryan J., Chiarion-Sileni, Vanna, Nyakas, Marta, Kahler, Katharina, Hauschild, Axel, Plummer, Ruth, Trojaniello, Claudia, Ascierto, Paolo A., Zimmer, Lisa, Schadendorf, Dirk, Allayous, Clara, Lebbe, Celeste, Maurichi, Andrea, Santinami, Mario, Roy, Severine, Robert, Caroline, Lesimple, Thierry, Patel, Sapna, Versluis, Judith M., Blank, Christian U., Khattak, Adnan, Van der Westhuizen, Andre, Carlino, Matteo S., Shackleton, Mark, Haydon, Andrew
Publicado 2020

Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer

por Willenbrock, Frances, Cox, Catrin M., Parkes, Eileen E., Wilhelm-Benartzi, Charlotte S., Abraham, Aswin G., Owens, Robert, Sabbagh, Ahmad, Jones, Christopher M., Hughes, Daniel L. I., Maughan, Tim, Hurt, Christopher N., O’Neill, Eric E., Mukherjee, Somnath
Publicado 2020

Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting the CDK9/STAT3 signalling pathway

por Yang, Lehe, Zhou, Feng, Zhuang, Yan, Liu, Yanan, Xu, Lingyuan, Zhao, Haiyang, Xiang, Youqun, Dai, Xuanxuan, Liu, Zhiguo, Huang, Xiaoying, Wang, Liangxing, Zhao, Chengguang
Publicado 2020

A Phase 1 study of gefitinib combined with durvalumab in EGFR TKI-naive patients with EGFR mutation-positive locally advanced/metastatic non-small-cell lung cancer

por Creelan, Benjamin C., Yeh, Tammie C., Kim, Sang-We, Nogami, Naoyuki, Kim, Dong-Wan, Chow, Laura Q. M., Kanda, Shintaro, Taylor, Rosemary, Tang, Weifeng, Tang, Mei, Angell, Helen K., Roudier, Martine P., Marotti, Marcelo, Gibbons, Don L.
Publicado 2020

A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours

por Robbrecht, Debbie G. J., Lopez, Juanita, Calvo, Emiliano, He, Xiaomin, Hiroshi, Hirai, Soni, Nital, Cook, Natalie, Dowlati, Afshin, Fasolo, Angelica, Moreno, Victor, Eskens, Ferry A. L. M., de Bono, Johann S.
Publicado 2020

Baseline immunity and impact of chemotherapy on immune microenvironment in cervical cancer

por Zhang, Yi, Yu, Minhua, Jing, Ying, Cheng, Jiejun, Zhang, Caiyan, Cheng, Lin, Lu, Haijiao, Cai, Mei-Chun, Wu, Jie, Wang, Wenjing, Lou, Weihua, Qiu, Lihua, Tan, Li, Lu, Huaiwu, Yin, Xia, Zhuang, Guanglei, Di, Wen
Publicado 2020

G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer

por Zhao, Junjie, Fu, Xuhong, Chen, Hao, Min, Lingqiang, Sun, Jie, Yin, Jingyi, Guo, Jianping, Li, Haojie, Tang, Zhaoqing, Ruan, Yuanyuan, Wang, Xuefei, Sun, Yihong, Huang, Liyu
Publicado 2020

A multicentre, randomised, open-label, parallel-group Phase 2b study of belotecan versus topotecan for recurrent ovarian cancer

por Kim, Hee Seung, Park, Sang-Yoon, Park, Chan-Yong, Kim, Young Tae, Kim, Beob-Jong, Song, Yong Jung, Kim, Byoung-Gie, Kim, Yong Beom, Cho, Chi-Heum, Kim, Jong-Hyeok, Song, Yong Sang
Publicado 2020

The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer

por Alexander, Peter G., Roseweir, Antonia K., Pennel, Kathryn A. F., van Wyk, Hester C., Powell, Arfon G. M. T., McMillan, Donald C., Horgan, Paul G., Kelly, Caroline, Hay, Jennifer, Sansom, Owen, Harkin, Andrea, Roxburgh, Campbell S. D., Graham, Janet, Church, David N., Tomlinson, Ian, Saunders, Mark, Iveson, Tim J., Edwards, Joanne, Park, James H.
Publicado 2020

A randomised phase 2b study comparing the efficacy and safety of belotecan vs. topotecan as monotherapy for sensitive-relapsed small-cell lung cancer

por Kang, Jin-Hyoung, Lee, Ki-Hyeong, Kim, Dong-Wan, Kim, Sang-We, Kim, Hye Ryun, Kim, Joo-Hang, Choi, Jin-Hyuk, An, Ho Jung, Kim, Jin-Soo, Jang, Joung-Soon, Kim, Bong-Seog, Kim, Heung Tae
Publicado 2020

A novel cancer preventative botanical mixture, TriCurin, inhibits viral transcripts and the growth of W12 cervical cells harbouring extrachromosomal or integrated HPV16 DNA

por Einbond, Linda Saxe, Zhou, Jing, Wu, Hsan-au, Mbazor, Emeka, Song, Guiyun, Balick, Michael, DeVoti, James A., Redenti, Stephen, Castellanos, Mario R.
Publicado 2020