A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol

por Shamash, J, Powles, T, Sarker, S J, Protheroe, A, Mithal, N, Mills, R, Beard, R, Wilson, P, Tranter, N, O'Brien, N, McFaul, S, Oliver, T
Publicado 2011

Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS)...

por Treasure, Tom, Lang-Lazdunski, Loic, Waller, David, Bliss, Judith M, Tan, Carol, Entwisle, James, Snee, Michael, O'Brien, Mary, Thomas, Gill, Senan, Suresh, O'Byrne, Ken, Kilburn, Lucy S, Spicer, James, Landau, David, Edwards, John, Coombes, Gill, Darlison, Liz, Peto, Julian
Publicado 2011

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

por Stevens, K N, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, V S, Hopper, J L, Dite, G S, Apicella, C, Southey, M C, Schmidt, M K, Broeks, A, Van ‘t Veer, L J, Tollenaar, R A E M, Fasching, P A, Beckmann, M W, Hein, A, Ekici, A B, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, M J, Chanock, S, Lissowska, J, Hunter, D J, Hoover, R N, Thomas, G D, Milne, R L, Pérez, JI Arias, González-Neira, A, Benítez, J, Burwinkel, B, Meindl, A, Schmutzler, R K, Bartrar, C R, Hamann, U, Ko, Y D, Brüning, T, Chang-Claude, J, Hein, R, Wang-Gohrke, S, Dörk, T, Schürmann, P, Bremer, M, Hillemanns, P, Bogdanova, N, Zalutsky, J V, Rogov, Y I, Antonenkova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V-M, Hartikainen, J, Chenevix-Trench, G, Chen, X, Peterlongo, P, Bonanni, B, Bernard, L, Manoukian, S, Wang, X, Cerhan, J, Vachon, C M, Olson, J, Giles, G G, Baglietto, L, McLean, C A, Severi, G, John, E M, Miron, A, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Andrulis, I, Knight, J A, Glendon, G, Mulligan, A M, Cox, A, Brock, I W, Elliott, G, Cross, S S, Pharoah, P P, Dunning, A M, Pooley, K A, Humphreys, M K, Wang, J, Kang, D, Yoo, K-Y, Noh, D-Y, Sangrajrang, S, Gabrieau, V, Brennan, P, McKay, J, Anton-Culver, H, Ziogas, A, Couch, F J, Easton, D F
Publicado 2011

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study

por Jakubowska, A, Rozkrut, D, Antoniou, A, Hamann, U, Scott, R J, McGuffog, L, Healy, S, Sinilnikova, O M, Rennert, G, Lejbkowicz, F, Flugelman, A, Andrulis, I L, Glendon, G, Ozcelik, H, Thomassen, M, Paligo, M, Aretini, P, Kantala, J, Aroer, B, von Wachenfeldt, A, Liljegren, A, Loman, N, Herbst, K, Kristoffersson, U, Rosenquist, R, Karlsson, P, Stenmark-Askmalm, M, Melin, B, Nathanson, K L, Domchek, S M, Byrski, T, Huzarski, T, Gronwald, J, Menkiszak, J, Cybulski, C, Serrano, P, Osorio, A, Cajal, T R, Tsitlaidou, M, Benítez, J, Gilbert, M, Rookus, M, Aalfs, C M, Kluijt, I, Boessenkool-Pape, J L, Meijers-Heijboer, H E J, Oosterwijk, J C, van Asperen, C J, Blok, M J, Nelen, M R, van den Ouweland, A M W, Seynaeve, C, van der Luijt, R B, Devilee, P, Easton, D F, Peock, S, Frost, D, Platte, R, Ellis, S D, Fineberg, E, Evans, D G, Lalloo, F, Eeles, R, Jacobs, C, Adlard, J, Davidson, R, Eccles, D, Cole, T, Cook, J, Godwin, A, Bove, B, Stoppa-Lyonnet, D, Caux-Moncoutier, V, Belotti, M, Tirapo, C, Mazoyer, S, Barjhoux, L, Boutry-Kryza, N, Pujol, P, Coupier, I, Peyrat, J-P, Vennin, P, Muller, D, Fricker, J-P, Venat-Bouvet, L, Johannsson, O Th, Isaacs, C, Schmutzler, R, Wappenschmidt, B, Meindl, A, Arnold, N, Varon-Mateeva, R, Niederacher, D, Sutter, C, Deissler, H, Preisler-Adams, S, Simard, J, Soucy, P, Durocher, F, Chenevix-Trench, G, Beesley, J, Chen, X, Rebbeck, T, Couch, F, Wang, X, Lindor, N, Fredericksen, Z, Pankratz, V S, Peterlongo, P, Bonanni, B, Fortuzzi, S, Peissel, B, Szabo, C, Mai, P L, Loud, J T, Lubinski, J
Publicado 2012

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergro...

por Biondi, Andrea, Schrappe, Martin, De Lorenzo, Paola, Castor, Anders, Lucchini, Giovanna, Gandemer, Virginie, Pieters, Rob, Stary, Jan, Escherich, Gabriele, Campbell, Myriam, Li, Chi-Kong, Vora, Ajay, Aricò, Maurizio, Röttgers, Silja, Saha, Vaskar, Valsecchi, Maria Grazia
Publicado 2012

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

por Cholesterol Treatment Trialists' (CTT) Collaborators
Publicado 2012

The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK

por Pirie, Kirstin, Peto, Richard, Reeves, Gillian K, Green, Jane, Beral, Valerie
Publicado 2013

Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomi...

por Seymour, Matthew T, Brown, Sarah R, Middleton, Gary, Maughan, Timothy, Richman, Susan, Gwyther, Stephen, Lowe, Catherine, Seligmann, Jennifer F, Wadsley, Jonathan, Maisey, Nick, Chau, Ian, Hill, Mark, Dawson, Lesley, Falk, Stephen, O'Callaghan, Ann, Benstead, Kim, Chambers, Philip, Oliver, Alfred, Marshall, Helen, Napp, Vicky, Quirke, Phil
Publicado 2013

Clinical significance of p95HER2 overexpression, PTEN loss and PI3K expression in p185HER2-positive metastatic breast cancer patients treated with trastuzumab-based therapies

por Tural, D, Serdengecti, S, Demirelli, F, Öztürk, T, İlvan, S, Turna, H, Özgüroglu, M, Büyükünal, E
Publicado 2014

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consort...

por Köbel, M, Madore, J, Ramus, S J, Clarke, B A, Pharoah, P D P, Deen, S, Bowtell, D D, Odunsi, K, Menon, U, Morrison, C, Lele, S, Bshara, W, Sucheston, L, Beckmann, M W, Hein, A, Thiel, F C, Hartmann, A, Wachter, D L, Anglesio, M S, Høgdall, E, Jensen, A, Høgdall, C, Kalli, K R, Fridley, B L, Keeney, G L, Fogarty, Z C, Vierkant, R A, Liu, S, Cho, S, Nelson, G, Ghatage, P, Gentry-Maharaj, A, Gayther, S A, Benjamin, E, Widschwendter, M, Intermaggio, M P, Rosen, B, Bernardini, M Q, Mackay, H, Oza, A, Shaw, P, Jimenez-Linan, M, Driver, K E, Alsop, J, Mack, M, Koziak, J M, Steed, H, Ewanowich, C, DeFazio, A, Chenevix-Trench, G, Fereday, S, Gao, B, Johnatty, S E, George, J, Galletta, L, Goode, E L, Kjær, S K, Huntsman, D G, Fasching, P A, Moysich, K B, Brenton, J D, Kelemen, L E
Publicado 2014

Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial

por Dearnaley, David, Syndikus, Isabel, Mossop, Helen, Khoo, Vincent, Birtle, Alison, Bloomfield, David, Graham, John, Kirkbride, Peter, Logue, John, Malik, Zafar, Money-Kyrle, Julian, O'Sullivan, Joe M, Panades, Miguel, Parker, Chris, Patterson, Helen, Scrase, Christopher, Staffurth, John, Stockdale, Andrew, Tremlett, Jean, Bidmead, Margaret, Mayles, Helen, Naismith, Olivia, South, Chris, Gao, Annie, Cruickshank, Clare, Hassan, Shama, Pugh, Julia, Griffin, Clare, Hall, Emma
Publicado 2016

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

por Kar, Siddhartha P, Adler, Emily, Tyrer, Jonathan, Hazelett, Dennis, Anton-Culver, Hoda, Bandera, Elisa V, Beckmann, Matthias W, Berchuck, Andrew, Bogdanova, Natalia, Brinton, Louise, Butzow, Ralf, Campbell, Ian, Carty, Karen, Chang-Claude, Jenny, Cook, Linda S, Cramer, Daniel W, Cunningham, Julie M, Dansonka-Mieszkowska, Agnieszka, Doherty, Jennifer Anne, Dörk, Thilo, Dürst, Matthias, Eccles, Diana, Fasching, Peter A, Flanagan, James, Gentry-Maharaj, Aleksandra, Glasspool, Rosalind, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Heitz, Florian, Hildebrandt, Michelle A T, Høgdall, Estrid, Høgdall, Claus K, Huntsman, David G, Jensen, Allan, Karlan, Beth Y, Kelemen, Linda E, Kiemeney, Lambertus A, Kjaer, Susanne K, Kupryjanczyk, Jolanta, Lambrechts, Diether, Levine, Douglas A, Li, Qiyuan, Lissowska, Jolanta, Lu, Karen H, Lubiński, Jan, Massuger, Leon F A G, McGuire, Valerie, McNeish, Iain, Menon, Usha, Modugno, Francesmary, Monteiro, Alvaro N, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Permuth, Jennifer B, Phelan, Catherine, Pike, Malcolm C, Poole, Elizabeth M, Ramus, Susan J, Risch, Harvey A, Rossing, Mary Anne, Salvesen, Helga B, Schildkraut, Joellen M, Sellers, Thomas A, Sherman, Mark, Siddiqui, Nadeem, Sieh, Weiva, Song, Honglin, Southey, Melissa, Terry, Kathryn L, Tworoger, Shelley S, Walsh, Christine, Wentzensen, Nicolas, Whittemore, Alice S, Wu, Anna H, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Freedman, Matthew L, Gayther, Simon A, Pharoah, Paul D P, Lawrenson, Kate
Publicado 2017

Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from...

por Bonaventure, Audrey, Harewood, Rhea, Stiller, Charles A, Gatta, Gemma, Clavel, Jacqueline, Stefan, Daniela C, Carreira, Helena, Spika, Devon, Marcos-Gragera, Rafael, Peris-Bonet, Rafael, Piñeros, Marion, Sant, Milena, Kuehni, Claudia E, Murphy, Michael F G, Coleman, Michel P, Allemani, Claudia
Publicado 2017

Evaluating wait times from screening to breast cancer diagnosis among women undergoing organised assessment vs usual care

por Chiarelli, Anna M, Muradali, Derek, Blackmore, Kristina M, Smith, Courtney R, Mirea, Lucia, Majpruz, Vicky, O'Malley, Frances P, Quan, May Lynn, Holloway, Claire MB
Publicado 2017

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

por Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Publicado 2017

Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label...

por Alderson, Derek, Cunningham, David, Nankivell, Matthew, Blazeby, Jane M, Griffin, S Michael, Crellin, Adrian, Grabsch, Heike I, Langer, Rupert, Pritchard, Susan, Okines, Alicia, Krysztopik, Richard, Coxon, Fareeda, Thompson, Joyce, Falk, Stephen, Robb, Clare, Stenning, Sally, Langley, Ruth E
Publicado 2017

Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial

por Newsome, Philip Noel, Fox, Richard, King, Andrew L, Barton, Darren, Than, Nwe-Ni, Moore, Joanna, Corbett, Christopher, Townsend, Sarah, Thomas, James, Guo, Kathy, Hull, Diana, Beard, Heather A, Thompson, Jacqui, Atkinson, Anne, Bienek, Carol, McGowan, Neil, Guha, Neil, Campbell, John, Hollyman, Dan, Stocken, Deborah, Yap, Christina, Forbes, Stuart John
Publicado 2017

Prediction of cervical cancer incidence in England, UK, up to 2040, under four scenarios: a modelling study

por Castanon, Alejandra, Landy, Rebecca, Pesola, Francesca, Windridge, Peter, Sasieni, Peter
Publicado 2017

Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

por Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M
Publicado 2018

3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial

por Iveson, Timothy J, Kerr, Rachel S, Saunders, Mark P, Cassidy, Jim, Hollander, Niels Henrik, Tabernero, Josep, Haydon, Andrew, Glimelius, Bengt, Harkin, Andrea, Allan, Karen, McQueen, John, Scudder, Claire, Boyd, Kathleen Anne, Briggs, Andrew, Waterston, Ashita, Medley, Louise, Wilson, Charles, Ellis, Richard, Essapen, Sharadah, Dhadda, Amandeep S, Harrison, Mark, Falk, Stephen, Raouf, Sherif, Rees, Charlotte, Olesen, Rene K, Propper, David, Bridgewater, John, Azzabi, Ashraf, Farrugia, David, Webb, Andrew, Cunningham, David, Hickish, Tamas, Weaver, Andrew, Gollins, Simon, Wasan, Harpreet S, Paul, James
Publicado 2018