Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal carcinoma treatment (ICON8): primary progression free survival analysis resul...

por Clamp, Andrew R, James, Elizabeth C, McNeish, Iain A, Dean, Andrew, Kim, Jae-Weon, O'Donnell, Dearbhaile M, Hook, Jane, Coyle, Christopher, Blagden, Sarah, Brenton, James D, Naik, Raj, Perren, Tim, Sundar, Sudha, Cook, Adrian D, Gopalakrishnan, Gosala S, Gabra, Hani, Lord, Rosemary, Dark, Graham, Earl, Helena M, Hall, Marcia, Banerjee, Susana, Glasspool, Rosalind M, Jones, Rachel, Williams, Sarah, Swart, Ann Marie, Stenning, Sally, Parmar, Mahesh, Kaplan, Richard, Ledermann, Jonathan A
Publicado 2019

Response-adapted intensification with cyclophosphamide, bortezomib, and dexamethasone versus no intensification in patients with newly diagnosed multiple myeloma (Myeloma XI): a mu...

por Jackson, Graham H, Davies, Faith E, Pawlyn, Charlotte, Cairns, David A, Striha, Alina, Collett, Corinne, Waterhouse, Anna, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Wilson, Jamie N, Jenner, Matthew W, Cook, Gordon, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Russell, Nigel H, Gregory, Walter M, Morgan, Gareth J
Publicado 2019

Weekly platinum-based chemotherapy versus 3-weekly platinum-based chemotherapy for newly diagnosed ovarian cancer (ICON8): quality-of-life results of a phase 3, randomised, control...

por Blagden, Sarah P, Cook, Adrian D, Poole, Christopher, Howells, Lesley, McNeish, Ian A, Dean, Andrew, Kim, Jae-Weon, O'Donnell, Dearbhaile M, Hook, Jane, James, Elizabeth C, White, Ian R, Perren, Timothy, Lord, Rosemary, Dark, Graham, Earl, Helena M, Hall, Marcia, Kaplan, Richard, Ledermann, Jonathan A, Clamp, Andrew R
Publicado 2020

Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial

por Turner, Nicholas C, Kingston, Belinda, Kilburn, Lucy S, Kernaghan, Sarah, Wardley, Andrew M, Macpherson, Iain R, Baird, Richard D, Roylance, Rebecca, Stephens, Peter, Oikonomidou, Olga, Braybrooke, Jeremy P, Tuthill, Mark, Abraham, Jacinta, Winter, Matthew C, Bye, Hannah, Hubank, Michael, Gevensleben, Heidrun, Cutts, Ros, Snowdon, Claire, Rea, Daniel, Cameron, David, Shaaban, Abeer, Randle, Katrina, Martin, Sue, Wilkinson, Katie, Moretti, Laura, Bliss, Judith M, Ring, Alistair
Publicado 2020

Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, mul...

por Smith, Ian, Robertson, John, Kilburn, Lucy, Wilcox, Maggie, Evans, Abigail, Holcombe, Chris, Horgan, Kieran, Kirwan, Cliona, Mallon, Elizabeth, Sibbering, Mark, Skene, Anthony, Vidya, Raghavan, Cheang, Maggie, Banerji, Jane, Morden, James, Sidhu, Kally, Dodson, Andrew, Bliss, Judith M, Dowsett, Mitch
Publicado 2020

MATRix–RICE therapy and autologous haematopoietic stem-cell transplantation in diffuse large B-cell lymphoma with secondary CNS involvement (MARIETTA): an international, single-arm...

por Ferreri, Andrés J M, Doorduijn, Jeanette K, Re, Alessandro, Cabras, Maria Giuseppina, Smith, Jeffery, Ilariucci, Fiorella, Luppi, Mario, Calimeri, Teresa, Cattaneo, Chiara, Khwaja, Jahanzaib, Botto, Barbara, Cellini, Claudia, Nassi, Luca, Linton, Kim, McKay, Pam, Olivieri, Jacopo, Patti, Caterina, Re, Francesca, Fanni, Alessandro, Singh, Vikram, Bromberg, Jacoline E C, Cozens, Kelly, Gastaldi, Elisabetta, Bernardi, Massimo, Cascavilla, Nicola, Davies, Andrew, Fox, Christopher P, Frezzato, Maurizio, Osborne, Wendy, Liberati, Anna Marina, Novak, Urban, Zambello, Renato, Zucca, Emanuele, Cwynarski, Kate
Publicado 2021

Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial

por Lamarca, Angela, Palmer, Daniel H, Wasan, Harpreet Singh, Ross, Paul J, Ma, Yuk Ting, Arora, Arvind, Falk, Stephen, Gillmore, Roopinder, Wadsley, Jonathan, Patel, Kinnari, Anthoney, Alan, Maraveyas, Anthony, Iveson, Tim, Waters, Justin S, Hobbs, Claire, Barber, Safia, Ryder, W David, Ramage, John, Davies, Linda M, Bridgewater, John A, Valle, Juan W
Publicado 2021

In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: result...

por Marks, David I, Clifton-Hadley, Laura, Copland, Mhairi, Hussain, Jiaull, Menne, Tobias F, McMillan, Andrew, Moorman, Anthony V, Morley, Nicholas, Okasha, Dina, Patel, Bela, Patrick, Pip, Potter, Michael N, Rowntree, Clare J, Kirkwood, Amy A, Fielding, Adele K
Publicado 2022

Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): A multicentre, randomised, controlled, phase 2 trial

por Fennell, Dean A., Porter, Catharine, Lester, Jason, Danson, Sarah, Blackhall, Fiona, Nicolson, Marianne, Nixon, Lisette, Gardner, Georgina, White, Ann, Griffiths, Gareth, Casbard, Angela
Publicado 2022

Personalised progression prediction in patients with monoclonal gammopathy of undetermined significance or smouldering multiple myeloma (PANGEA): a retrospective, multicohort study

por Cowan, Annie, Ferrari, Federico, Freeman, Samuel S, Redd, Robert, El-Khoury, Habib, Perry, Jacqueline, Patel, Vidhi, Kaur, Priya, Barr, Hadley, Lee, David J, Lightbody, Elizabeth, Downey, Katelyn, Argyelan, David, Theodorakakou, Foteini, Fotiou, Despina, Liacos, Christine Ivy, Kanellias, Nikolaos, Chavda, Selina J, Ainley, Louise, Sandecká, Viera, Pospíšilová, Lenka, Minarik, Jiri, Jungova, Alexandra, Radocha, Jakub, Spicka, Ivan, Nadeem, Omar, Yong, Kwee, Hájek, Roman, Kastritis, Efstathios, Marinac, Catherine R, Dimopoulos, Meletios A, Get, Gad, Trippa, Lorenzo, Ghobrial, Irene M
Publicado 2023

Phase III pilot study of dose escalation using conformal radiotherapy in prostate cancer: PSA control and side effects

por Dearnaley, D P, Hall, E, Lawrence, D, Huddart, R A, Eeles, R, Nutting, C M, Gadd, J, Warrington, A, Bidmead, M, Horwich, A
Publicado 2005

Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial

por Tobias, Jeffrey S, Monson, Kathryn, Gupta, Nirmal, MacDougall, Hugh, Glaholm, John, Hutchison, Iain, Kadalayil, Latha, Hackshaw, Allan
Publicado 2009

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

por Agarwal, D, Pineda, S, Michailidou, K, Herranz, J, Pita, G, Moreno, L T, Alonso, M R, Dennis, J, Wang, Q, Bolla, M K, Meyer, K B, Menéndez-Rodríguez, P, Hardisson, D, Mendiola, M, González-Neira, A, Lindblom, A, Margolin, S, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, Matsuo, K, Ito, H, Iwata, H, Kondo, N, Hartman, M, Hui, M, Lim, W Y, T-C Iau, P, Sawyer, E, Tomlinson, I, Kerin, M, Miller, N, Kang, D, Choi, J-Y, Park, S K, Noh, D-Y, Hopper, J L, Schmidt, D F, Makalic, E, Southey, M C, Teo, S H, Yip, C H, Sivanandan, K, Tay, W-T, Brauch, H, Brüning, T, Hamann, U, Dunning, A M, Shah, M, Andrulis, I L, Knight, J A, Glendon, G, Tchatchou, S, Schmidt, M K, Broeks, A, Rosenberg, E H, van't Veer, L J, Fasching, P A, Renner, S P, Ekici, A B, Beckmann, M W, Shen, C-Y, Hsiung, C-N, Yu, J-C, Hou, M-F, Blot, W, Cai, Q, Wu, A H, Tseng, C-C, Van Den Berg, D, Stram, D O, Cox, A, Brock, I W, Reed, M W R, Muir, K, Lophatananon, A, Stewart-Brown, S, Siriwanarangsan, P, Zheng, W, Deming-Halverson, S, Shrubsole, M J, Long, J, Shu, X-O, Lu, W, Gao, Y-T, Zhang, B, Radice, P, Peterlongo, P, Manoukian, S, Mariette, F, Sangrajrang, S, McKay, J, Couch, F J, Toland, A E, Yannoukakos, D, Fletcher, O, Johnson, N, Silva, I dos Santos, Peto, J, Marme, F, Burwinkel, B, Guénel, P, Truong, T, Sanchez, M, Mulot, C, Bojesen, S E, Nordestgaard, B G, Flyer, H, Brenner, H, Dieffenbach, A K, Arndt, V, Stegmaier, C, Mannermaa, A, Kataja, V, Kosma, V-M, Hartikainen, J M, Lambrechts, D, Yesilyurt, B T, Floris, G, Leunen, K, Chang-Claude, J, Rudolph, A, Seibold, P, Flesch-Janys, D, Wang, X, Olson, J E, Vachon, C, Purrington, K, Giles, G G, Severi, G, Baglietto, L, Haiman, C A, Henderson, B E, Schumacher, F, Le Marchand, L, Simard, J, Dumont, M, Goldberg, M S, Labrèche, F, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Devilee, P, Tollenaar, R A E M, Seynaeve, C, García-Closas, M, Chanock, S J, Lissowska, J, Figueroa, J D, Czene, K, Eriksson, M, Humphreys, K, Darabi, H, Hooning, M J, Kriege, M, Collée, J M, Tilanus-Linthorst, M, Li, J, Jakubowska, A, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Nevanlinna, H, Muranen, T A, Aittomäki, K, Blomqvist, C, Bogdanova, N, Dörk, T, Hall, P, Chenevix-Trench, G, Easton, D F, Pharoah, P D P, Arias-Perez, J I, Zamora, P, Benítez, J, Milne, R L
Publicado 2014

Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial

por Glover, Mark, Smerdon, Gary R, Andreyev, H Jervoise, Benton, Barbara E, Bothma, Pieter, Firth, Oliver, Gothard, Lone, Harrison, John, Ignatescu, Mihaela, Laden, Gerard, Martin, Sue, Maynard, Lauren, McCann, Des, Penny, Christine E L, Phillips, Spencer, Sharp, Grace, Yarnold, John
Publicado 2016

Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

por Jacobs, Ian J, Menon, Usha, Ryan, Andy, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Kalsi, Jatinderpal K, Amso, Nazar N, Apostolidou, Sophia, Benjamin, Elizabeth, Cruickshank, Derek, Crump, Danielle N, Davies, Susan K, Dawnay, Anne, Dobbs, Stephen, Fletcher, Gwendolen, Ford, Jeremy, Godfrey, Keith, Gunu, Richard, Habib, Mariam, Hallett, Rachel, Herod, Jonathan, Jenkins, Howard, Karpinskyj, Chloe, Leeson, Simon, Lewis, Sara J, Liston, William R, Lopes, Alberto, Mould, Tim, Murdoch, John, Oram, David, Rabideau, Dustin J, Reynolds, Karina, Scott, Ian, Seif, Mourad W, Sharma, Aarti, Singh, Naveena, Taylor, Julie, Warburton, Fiona, Widschwendter, Martin, Williamson, Karin, Woolas, Robert, Fallowfield, Lesley, McGuire, Alistair J, Campbell, Stuart, Parmar, Mahesh, Skates, Steven J
Publicado 2016

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis

por Gharahkhani, Puya, Fitzgerald, Rebecca C, Vaughan, Thomas L, Palles, Claire, Gockel, Ines, Tomlinson, Ian, Buas, Matthew F, May, Andrea, Gerges, Christian, Anders, Mario, Becker, Jessica, Kreuser, Nicole, Noder, Tania, Venerito, Marino, Veits, Lothar, Schmidt, Thomas, Manner, Hendrik, Schmidt, Claudia, Hess, Timo, Böhmer, Anne C, Izbicki, Jakob R, Hölscher, Arnulf H, Lang, Hauke, Lorenz, Dietmar, Schumacher, Brigitte, Hackelsberger, Andreas, Mayershofer, Rupert, Pech, Oliver, Vashist, Yogesh, Ott, Katja, Vieth, Michael, Weismüller, Josef, Nöthen, Markus M, Attwood, Stephen, Barr, Hugh, Chegwidden, Laura, de Caestecker, John, Harrison, Rebecca, Love, Sharon B, MacDonald, David, Moayyedi, Paul, Prenen, Hans, Watson, R G Peter, Iyer, Prasad G, Anderson, Lesley A, Bernstein, Leslie, Chow, Wong-Ho, Hardie, Laura J, Lagergren, Jesper, Liu, Geoffrey, Risch, Harvey A, Wu, Anna H, Ye, Weimin, Bird, Nigel C, Shaheen, Nicholas J, Gammon, Marilie D, Corley, Douglas A, Caldas, Carlos, Moebus, Susanne, Knapp, Michael, Peters, Wilbert H M, Neuhaus, Horst, Rösch, Thomas, Ell, Christian, MacGregor, Stuart, Pharoah, Paul, Whiteman, David C, Jankowski, Janusz, Schumacher, Johannes
Publicado 2016

Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer in the randomised UK TACT2...

por Cameron, David, Morden, James P, Canney, Peter, Velikova, Galina, Coleman, Robert, Bartlett, John, Agrawal, Rajiv, Banerji, Jane, Bertelli, Gianfilippo, Bloomfield, David, Brunt, A Murray, Earl, Helena, Ellis, Paul, Gaunt, Claire, Gillman, Alexa, Hearfield, Nicholas, Laing, Robert, Murray, Nicholas, Couper, Niki, Stein, Robert C, Verrill, Mark, Wardley, Andrew, Barrett-Lee, Peter, Bliss, Judith M
Publicado 2017

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Globa...

por Wasan, Harpreet S, Gibbs, Peter, Sharma, Navesh K, Taieb, Julien, Heinemann, Volker, Ricke, Jens, Peeters, Marc, Findlay, Michael, Weaver, Andrew, Mills, Jamie, Wilson, Charles, Adams, Richard, Francis, Anne, Moschandreas, Joanna, Virdee, Pradeep S, Dutton, Peter, Love, Sharon, Gebski, Val, Gray, Alastair, van Hazel, Guy, Sharma, Ricky A
Publicado 2017

Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial

por Mateo, Joaquin, Porta, Nuria, Bianchini, Diletta, McGovern, Ursula, Elliott, Tony, Jones, Robert, Syndikus, Isabel, Ralph, Christy, Jain, Suneil, Varughese, Mohini, Parikh, Omi, Crabb, Simon, Robinson, Angus, McLaren, Duncan, Birtle, Alison, Tanguay, Jacob, Miranda, Susana, Figueiredo, Ines, Seed, George, Bertan, Claudia, Flohr, Penny, Ebbs, Berni, Rescigno, Pasquale, Fowler, Gemma, Ferreira, Ana, Riisnaes, Ruth, Pereira, Rita, Curcean, Andra, Chandler, Robert, Clarke, Matthew, Gurel, Bora, Crespo, Mateus, Nava Rodrigues, Daniel, Sandhu, Shahneen, Espinasse, Aude, Chatfield, Peter, Tunariu, Nina, Yuan, Wei, Hall, Emma, Carreira, Suzanne, de Bono, Johann S
Publicado 2020

Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phas...

por Bridgewater, John A, Pugh, Siân A, Maishman, Tom, Eminton, Zina, Mellor, Jane, Whitehead, Amy, Stanton, Louise, Radford, Michael, Corkhill, Andrea, Griffiths, Gareth O, Falk, Stephen, Valle, Juan W, O'Reilly, Derek, Siriwardena, Ajith K, Hornbuckle, Joanne, Rees, Myrddin, Iveson, Timothy J, Hickish, Tamas, Garden, O James, Cunningham, David, Maughan, Timothy S, Primrose, John N
Publicado 2020