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  1. 2021
    “…We have identified five candidate proteinaceous toxins, one of which showed high similarity to a previously characterized phytotoxin. …”
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  2. 2022
    por Williamson, Diane
    Publicado 2014
    “…This review considers the steps required to evaluate a candidate biodefense vaccine or therapy as it emerges from the research phase, in order to transition it to development. …”
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  3. 2023
    “…AIMS: The present study examined associations between these candidates, mood disorder diagnoses, cognition, and fronto-limbic regions implicated in affect regulation. …”
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  4. 2024
    “…BACKGROUND: GABRB3 is a position candidate gene at chromosome 15q12 that has been implicated in the neurobiology of autism spectrum disorders (ASD). …”
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  5. 2025
    “…Significant improvements in candidate ranking were demonstrated for 41 small test molecules when the CASE system was supplemented by a natural product-likeness filter. …”
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  6. 2026
    “…To more finely map this QTL region and identify candidate genes for this trait, comparative mapping of pig and human chromosomes was performed in the present study. …”
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  7. 2027
    “…PURPOSE: To identify the spectrum and frequency of five candidate genes in Chinese patients with congenital ectopia lentis (EL). …”
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  8. 2028
    “…PURPOSE: We sought to evaluate the clinical usefulness of decision making by a multidisciplinary heart team for identifying potential candidates for transcatheter aortic valve implantation (TAVI) in patients with symptomatic severe aortic stenosis. …”
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  9. 2029
    “…Therefore, automated methods are needed that reliably predict disease gene candidates based on available data. We have recently developed Exomiser as a tool for identifying causative variants from exome analysis results by filtering and prioritising using a number of criteria including the phenotype similarity between the disease and mouse mutants involving the gene candidates. …”
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  10. 2030
  11. 2031
    “…First isolated in 1926, Clostridium thermocellum has recently received increased attention as a high utility candidate for use in consolidated bioprocessing (CBP) applications. …”
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  12. 2032
  13. 2033
    “…The results suggest that this approach may be a useful tool in the evaluation of biological processes of interest and selection of process-related candidate genes.…”
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  14. 2034
  15. 2035
  16. 2036
    “…Our results suggest that the pattern of metabolites found in urine is significantly changed following FA inhalation, and hippuric acid and cinnamoylglycine might represent potential biomarker candidates for FA exposure.…”
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  17. 2037
    “…The significant nodes and bioactive small molecules may be drug targets and candidate agents for T2D treatment.…”
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  18. 2038
  19. 2039
    “…We present a new tool for hepatocarcinogenicity evaluation of drug candidates in rodents. ToxDBScan is a web tool offering quick and easy similarity screening of new drug candidates against two large-scale public databases, which contain expression profiles for substances with known carcinogenic profiles: TG-GATEs and DrugMatrix. …”
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  20. 2040
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