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2101por Tian, HonglaiEnlace del recurso
Publicado 2016
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2102por Trojan, Daniela, Schreiber, Lars, Bjerg, Jesper T., Bøggild, Andreas, Yang, Tingting, Kjeldsen, Kasper U., Schramm, Andreas“…Based on these results, it is proposed to accommodate cable bacteria within two novel candidate genera: the mostly marine “Candidatus Electrothrix”, with four candidate species, and the mostly freshwater “Candidatus Electronema”, with two candidate species. …”
Publicado 2016
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2103“…In this manuscript, we describe molecular pharmacology, in vitro ADME, pharmacokinetics in animals and humans (part of the Phase I clinical studies), bio-distribution, bioavailability, in vivo efficacy, and safety profile of the multimodal drug candidate, AVN-101. We have carried out development of a next generation drug candidate with a multi-targeted mechanism of action, to treat CNS disorders. …”
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2104por Han, Lin, Cao, Chunwei, Jia, Zhaotong, Liu, Shiguo, Liu, Zhen, Xin, Ruosai, Wang, Can, Li, Xinde, Ren, Wei, Wang, Xuefeng, Li, Changgui“…Here, we performed two-stage analysis to determine whether variations in candidate genes in the 4q25 region are associated with gout in a male Chinese Han population. …”
Publicado 2016
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2105por Cedernaes, Jonathan, Osorio, Ricardo S., Varga, Andrew W., Kam, Korey, Schioöth, Helgi B., Benedict, ChristianEnlace del recurso
Publicado 2016
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2106por Mohammadpour, Mehrdad, Heidari, Zahra, Mohammad-Rabei, Hossein, Jafarzadehpur, Ebrahim, Jabbarvand, Mahmoud, Hashemi, Hassan, Khabazkhoob, Mehdi“…PURPOSE: To evaluate the correlation between refractive, corneal, and residual astigmatism and higher order aberrations (HOA) in refractive surgery candidates. METHODS: Three hundred and seventy-five eyes of 188 patients aged 28.2 ± 6.24 years with a predominance of females (62.7%) were enrolled in this study. …”
Publicado 2016
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2107“…In addition, we identified two vernalizaiton–related genes (LoSVP and LoVRN1) from the cDNA library, which appear to be promising candidates for playing key roles in the development and response of flowering in Oriental lily plants, and LoSVP had a function in delaying flowering but LoVRN1could promote flowering early. …”
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2108
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2109por Yoshida, Takegawa, Han, Fei, Zhou, Ziwu, Aksoy, Olcay, Suh, William M, Hu, Peng, Finn, J PaulEnlace del recurso
Publicado 2016
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2110por Wickerson, Lisa, Rozenberg, Dmitry, Janaudis-Ferreira, Tania, Deliva, Robin, Lo, Vincent, Beauchamp, Gary, Helm, Denise, Gottesman, Chaya, Mendes, Polyana, Vieira, Luciana, Herridge, Margaret, Singer, Lianne G, Mathur, Sunita“…Physical rehabilitation of lung transplant candidates and recipients plays an important in optimizing physical function prior to transplant and facilitating recovery of function post-transplant. …”
Publicado 2016
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2111por Tsai, Ellen A., Gilbert, Melissa A., Grochowski, Christopher M., Underkoffler, Lara A., Meng, He, Zhang, Xiaojie, Wang, Michael M., Shitaye, Hailu, Hankenson, Kurt D., Piccoli, David, Lin, Henry, Kamath, Binita M., Devoto, Marcella, Spinner, Nancy B., Loomes, Kathleen M.“…These results implicate THBS2 as a plausible candidate genetic modifier of liver disease severity in Alagille syndrome.…”
Publicado 2016
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2112por Chen, Liuxi, Wang, Lan, Shion, Henry, Yu, Chuanfei, Yu, Ying Qing, Zhu, Lei, Li, Meng, Chen, Weibin, Gao, Kai“…As described here, we performed extensive characterization of a lysine conjugated ADC, ado-trastuzumab emtansine, and compared its CQAs between the reference product (Kadcyla®) and a candidate biosimilar. Primary amino acid sequences, drug-to-antibody ratios (DARs), conjugation sites and site occupancy data were acquired and compared by LC/MS methods. …”
Publicado 2016
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2113por PASSERI, Celso Roberto, ANDRADE, Jacira Alves Caracik de Camargo, TOMAL, Karla Thaíza, PRACUCHO, Eduardo Marcucci, de CAMPOS, Livia Paschoalino, SALES-PERES, Silvia Helena de Carvalho“…AIM: Assess masticatory function of obese candidates to bariatric surgery, who belong to distinct socioeconomic class range, in order to recognize hazard factors and the bias of socioeconomic factor in this context. …”
Publicado 2016
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2114
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2115por Dastgheib, Seyed Alireza, Gartland, Alison, Tabei, Seyed Mohammad Bagher, Omrani, Gholamhossein Ranjbar, Teare, Marion Dawn“…We selected to study the association with 21 single nucleotide polymorphisms (SNPs) located in the 7 candidate genes LRP5, RANK, RANKL, OPG, P2RX7, VDR, and ESR1. …”
Publicado 2016
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2116por Li, Tingting, Liu, Chunjie, Xu, Yuejuan, Guo, Qianqian, Chen, Sun, Sun, Kun, Xu, Rang“…Further mutation screening of these two candidate genes in 143 atrial septal defect patients, two heterozygous mutations NKX2-6 (c.1A > T) and NRG1 (c.1652G > A) were identified. …”
Publicado 2016
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2117por Steponaitis, Giedrius, Kazlauskas, Arunas, Skiriute, Daina, Valiulyte, Indre, Skauminas, Kestutis, Tamasauskas, Arimantas, Vaitkiene, Paulina“…The establishment of molecular markers may identify variables required to improve tumour characterization and subtyping, and may aid to specify targets for improved treatment with essential prognostic value for patient survival. One such candidate is testin (TES), which was reported to have prognostic value for glioblastoma patients. …”
Publicado 2016
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2118por Matsson, Hans, Söderhäll, Cilla, Einarsdottir, Elisabet, Lamontagne, Maxime, Gudmundsson, Sanna, Backman, Helena, Lindberg, Anne, Rönmark, Eva, Kere, Juha, Sin, Don, Postma, Dirkje S., Bossé, Yohan, Lundbäck, Bo, Klar, Joakim“…CONCLUSION: Our data replicate previous result suggesting CHRNA5 as a candidate gene for COPD and rs8040868 as a risk variant for the development of COPD in the Swedish population. …”
Publicado 2016
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2119“…Thus, a novel approach in designing of an effective vaccine or allergen shot candidate against A. fumigatus is needed. Using immunoinformatics approaches from the characterized A. fumigatus allergens, we have mapped epitopic regions to predict potential peptides that elicit both Aspergillus-specific T cells and B cell immune response. …”
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2120por Liang, Li, Song, Liting, Yang, Yi, Tian, Ling, Li, Xiaoyuan, Wu, Songfeng, Huang, Wenxun, Ren, Hong, Tang, Ni, Ding, Keyue“…We previously prioritized five personalized candidate mutation-driver genes in a hyper-mutated hepatocellular carcinoma patient using a multi-omics strategy. …”
Publicado 2016
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