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  1. 2301
    “…BACKGROUND: Genetic association studies for gastroschisis have highlighted several candidate variants. However, genetic basis in gastroschisis from noninvestigated heritable factors could provide new insights into the human biology for this birth defect. …”
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    Whole exome sequencing identifies multiple novel candidate genes in familial gastroschisis
  2. 2302
    “…CONCLUSIONS: Our results indicated that the heterologous prime-boost strategy induced higher levels of humoral and cellular immune responses and better protection against TMUV infection in ducks than the homologous prime-boost strategies, suggesting that the heterologous prime-boost strategy is an important candidate for the design of a novel vaccine strategy against TMUV.…”
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    Heterologous prime-boost: an important candidate immunization strategy against Tembusu virus
  3. 2303
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    Mechanistic Paradigms of Natural Plant Metabolites as Remedial Candidates for Systemic Lupus Erythromatosus
  4. 2304
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    Identification of PROS1 as a Novel Candidate Gene for Juvenile Retinitis Pigmentosa
  5. 2305
    “…Herein, we summarize the DR process and explore several repurposed drugs with different epigenetic targets that constitute promising candidates for cancer treatment, highlighting their mechanisms of action.…”
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    Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?
  6. 2306
    “…We propose that Tregs may be an effective, novel candidate for cell-based therapy in pre-clinical kidney injury models.…”
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    Regulatory T Cells as a Novel Candidate for Cell-Based Therapy in Kidney Disease
  7. 2307
    “…To date, several studies focus on the application of loss-of-function genome-wide screenings to identify key (hub) “fitness” genes essential for BC progression and representing candidate drug targets to overcome lack of response, or acquired resistance, to current therapies. …”
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    Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer
  8. 2308
    “…These analyses suggest four prime candidate oncogenic RBPs with partially validated target potential: APOBEC1, IGF2BP1 and 3, and OASL.…”
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    RNA Binding Proteins as Drivers and Therapeutic Target Candidates in Pancreatic Ductal Adenocarcinoma
  9. 2309
    “…Thus, in the present review, we tried to give an overview of the conventional pharmacotherapy for mucus-hypersecretory diseases and recent research results on searching for the novel candidate agents for controlling of pulmonary mucus hypersecretion, aiming to shed light on the potential efficacious pharmacotherapy of mucus-hypersecretory diseases.…”
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    Recent Advances in the Development of Novel Drug Candidates for Regulating the Secretion of Pulmonary Mucus
  10. 2310
    “…The efficiency of the candidate vaccine to trigger an effective immune response was assessed by an in silico immune simulation. …”
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    A candidate multi-epitope vaccine against SARS-CoV-2
  11. 2311
    “…Malnutrition in lung transplant (LTx) candidates is an important risk factor for adverse outcomes. …”
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    Evaluation of Malnutrition Risk in Lung Transplant Candidates Using the Nutritional Risk Index
  12. 2312
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    Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines
  13. 2313
    “…In the present study the aim was to validate the use of catalase expression as a marker and to identify new candidate genes as additional markers to catalase, related to H(2)O(2) resistance in L. salmonis. …”
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    Candidate genes for monitoring hydrogen peroxide resistance in the salmon louse, Lepeophtheirus salmonis
  14. 2314
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    MicroRNA-154: A Novel Candidate for Diagnosis and Therapy of Human Cancers
  15. 2315
    “…Therefore, this research focused on characterizing positional candidate genes underlying qhir8. Pursuing this goal, a strong candidate for qhir8, GRMZM2G435294 (MYO), was silenced by RNAi. …”
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    MYO, a Candidate Gene for Haploid Induction in Maize Causes Male Sterility
  16. 2316
    “…Thus, in this article, by utilizing the in-silico approach, a vaccine candidate for SARS-CoV-2 has been proposed. Moreover, the effectiveness and safety measures of our proposed epitopic vaccine candidate have been evaluated by in-silico tools and servers (AllerTOP and AllergenFP servers). …”
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    A SARS-CoV-2 vaccine candidate: In-silico cloning and validation
  17. 2317
    por Yang, Heli, Xu, Xiaoxi, Ran, Xin, Ran, Yuping
    Publicado 2020
    “…Candidal granuloma is a rare and refractory disease in clinical practice, usually reported in immunocompromised patients. …”
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    Successful Treatment of Refractory Candidal Granuloma by Itraconazole and Terbinafine in Combination with Hyperthermia and Cryotherapy
  18. 2318
    “…Based on the overall results collected, a subset of candidate sourdough starter cultures for the baking industry was selected, including Lb. brevis LD66 and L. citreum PB220, which showed high phytase activity and positive EPS production.…”
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    Selection of cereal-sourced lactic acid bacteria as candidate starters for the baking industry
  19. 2319
    “…CONCLUSIONS AND CLINICAL RELEVANCE: BTH2 is a promising hybrid vaccine candidate for immunotherapy of Blomia allergy. However, further pre‐clinical studies addressing its efficacy and safety are needed.…”
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    A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate
  20. 2320
    “…In this study, we sequenced and analyzed the antennal transcriptomes of both male and female adults of H. halys to better understand the olfactory mechanisms in this species. A total of 241 candidate chemosensory genes were identified, including 138 odorant receptors (ORs), 24 ionotropic receptors (IRs), 15 gustatory receptors (GRs), 44 odorant-binding proteins (OBPs), 17 chemosensory proteins (CSPs), and three sensory neuron membrane proteins (SNMPs). …”
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    Identification of Candidate Olfactory Genes in the Antennal Transcriptome of the Stink Bug Halyomorpha halys
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