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344“…An immunoinformatics approach was employed to design a theoretical multi-epitope vaccine candidate. This vaccine candidate consists of linear B-cell epitope, TH cells epitope and CTL of reported potential vaccine candidates. …”
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345por Polishchuk, Valentina B., Kostinov, Mikhail P., Ryzhov, Aleksey A., Karchevskaya, Natalia A., Solov’eva, Irina L., Cherdantsev, Alexander P., Kostinova, Aristitsa M., Poddubikov, Arseniy A.“…Overall, 19% of lung transplant candidates, mostly young people and cystic fibrosis patients, did not have protective immunity against measles.…”
Publicado 2023
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346“…We identify similar candidate strains to those proposed by the World Health Organization, suggesting that this approach can help inform vaccine strain selection.…”
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351por Lesueur, Fabienne, Oudot, Tiphaine, Heath, Simon, Foglio, Mario, Lathrop, Mark, Prud'homme, Jean-François, Fischer, Judith“…When positive association was obtained for a SNP, candidate genes nearby were explored more in detail using a denser set of SNPs. …”
Publicado 2007
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352por Fernandez, Francesca, Curtain, Robert P, Colson, Natalie J, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn R“…In this study, we have undertaken a large genomic investigation involving candidate genes that lie within the chromosome 1q23 and 1q31 regions using an association analysis approach. …”
Publicado 2007
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353por Hancock, Angela M, Witonsky, David B, Gordon, Adam S, Eshel, Gidon, Pritchard, Jonathan K, Coop, Graham, Di Rienzo, Anna“…Nevertheless, our results are consistent with the idea that climate has been an important selective pressure acting on candidate genes for common metabolic disorders.…”
Publicado 2008
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354“…CONCLUSION: We find that evolutionarily conserved gene co-expression prioritizes disease candidate genes better than human gene co-expression alone, and provide the integrated data as a new resource for disease gene prioritization tools.…”
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355por Furney, Simon J., Calvo, Borja, Larrañaga, Pedro, Lozano, Jose A., Lopez-Bigas, Nuria“…Furthermore, the classifiers also discriminate candidate cancer genes from a recent mutational screen from other human genes. …”
Publicado 2008
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357“…The benefits of marker assisted selection (MAS) are evaluated under realistic assumptions in schemes where the genetic contributions of the candidates to selection are optimised for maximising the rate of genetic progress while restricting the accumulation of inbreeding. …”
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358“…These proteins, only some of which have been detected in plasma to date, represent a population of candidate plasma biomarkers that could be useful in early cancer detection and monitoring given sufficiently sensitive specific assays. …”
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359por Desler, Claus, Suravajhala, Prashanth, Sanderhoff, May, Rasmussen, Merete, Rasmussen, Lene Juel“…Therefore our in silico selection strategy can be used to select the most promising candidates for subsequent in vitro and in vivo analyses.…”
Publicado 2009
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