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541por Tripathy, Ashutosh, Dash, Jayalaxmi, Kancharla, Sudhakar, Kolli, Prachetha, Mahajan, Deviyani, Senapati, Shantibhusan, Jena, Manoj Kumar“…Probiotics have been used for a long time due to their beneficial health effects, and now, it has become a popular candidate for the preventive and therapeutic treatment of CRC. …”
Publicado 2021
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542por Basak, Srijita, Deb, Debashrito, Narsaria, Utkarsh, Kar, Tamalika, Castiglione, Filippo, Sanyal, Indraneel, Bade, Pratap D., Srivastava, Anurag P.“…In this study, the CotE, SlpA and FliC proteins are chosen to form a multivalent, multi-epitopic, chimeric vaccine candidate using the immunoinformatics approach. The overall reliability of the candidate vaccine was validated in silico and the molecular dynamics simulation verified the stability of the vaccine designed. …”
Publicado 2021
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544“…Among them, Ru(II/III)-based complexes have emerged as promising anticancer drug candidates due to their potential anticancer properties and selective cytotoxic activity. …”
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546“…Globally major pharmaceutical firms are engrossed for development of a potent vaccine candidate. This review highlights on various vaccine candidates under clinical trials.…”
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547por Vijayan, Poornima, Hack, Saidah, Yao, Tony, Qureshi, Mohammad Azfar, Paterson, Andrew D., John, Rohan, Davenport, Bernard, Lennon, Rachel, Pei, York, Barua, Moumita“…Two of these variants, in LAMA2 and LOXL4, remained as candidates after segregation analysis and encode extracellular matrix proteins of the glomerulus. …”
Publicado 2021
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548“…This review provides an overview of the current progress in development of PRR agonists as vaccine adjuvants, the molecular mechanisms that underlie activation of immune responses, and the enhancement of vaccine efficacy by these potential adjuvant candidates.…”
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549por Priya, Ratna, Jain, Vaishali, Akhtar, Javed, Chauhan, Geeta, Sakhuja, Puja, Goyal, Surbhi, Agarwal, Anil Kumar, Javed, Amit, Jain, Ankit P., Polisetty, Ravindra Varma, Sirdeshmukh, Ravi, Kar, Sudeshna, Gautam, PoonamEnlace del recurso
Publicado 2021
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550por Takashima, Eizo, Tachibana, Mayumi, Morita, Masayuki, Nagaoka, Hikaru, Kanoi, Bernard N., Tsuboi, Takafumi“…Therefore, novel approaches to accelerate TBV research and development are urgently needed, especially novel TBV candidate discovery. In this mini review we summarize the progress in TBV research and development, novel TBV candidate discovery, and discuss how to accelerate novel TBV candidate discovery.…”
Publicado 2021
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551por Grace, Cooper Alastair, Forrester, Sarah, Silva, Vladimir Costa, Carvalho, Kátia Silene Sousa, Kilford, Hannah, Chew, Yen Peng, James, Sally, Costa, Dorcas L, Mottram, Jeremy C, Costa, Carlos C H N, Jeffares, Daniel C“…We then apply multiple diversity metrics to identify candidate genes with robust signatures of balancing selection, identifying a curated set of 24 genes with robust signatures. …”
Publicado 2021
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552por Maizels, Rick M.Enlace del recurso
Publicado 2021
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553“…This study was conducted to identify candidate genes for AD diagnosis and underlying molecular mechanisms. …”
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554por Paddock, MichaelEnlace del recurso
Publicado 2022
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555por Norkeviciene, Audrone, Gocentiene, Romena, Sestokaite, Agne, Sabaliauskaite, Rasa, Dabkeviciene, Daiva, Jarmalaite, Sonata, Bulotiene, Giedre“…Background and Objectives: The aim of this systematic review was to analyse which candidate genes were examined in genetic association studies and their association with major depressive disorder (MDD). …”
Publicado 2022
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556por Chen, Yingqing, Tang, Minli, Yuan, Shuo, Fu, Shuang, Li, Yifei, Li, You, Wang, Qi, Cao, Yuying, Liu, Liping, Zhang, QinggaoEnlace del recurso
Publicado 2022
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557“…Antiviral medications are the candidate therapies for the management of COVID‐19. …”
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558por Wen, Zilu, Wu, Liwei, Wang, Lin, Ou, Qinfang, Ma, Hui, Wu, Qihang, Zhang, Shulin, Song, Yanzheng“…Based on our previous study, the intersect between WGCNA and differential gene analysis could be used as candidate biomarkers. Then, the enzyme-linked immunosorbent assay was used to validate candidate biomarkers, and receiver operating characteristic was used to assess diagnose ability of candidate biomarkers. …”
Publicado 2022
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559por Rushakoff, Joshua A., Gragert, Loren, Pando, Marcelo J., Stewart, Darren, Huang, Edmund, Kim, Irene, Jordan, Stanley, Lindblad, Kelsi, Zhang, Xiaohai, Lalli, Peter, Patel, Jignesh K., Kobashigawa, Jon A., Kransdorf, Evan P.“…Within mildly, highly, or extremely sensitized candidates, women displayed a higher relative abundance of HLA homozygosity at multiple HLA loci as compared with men, with attenuation of this effect in Black candidates. …”
Publicado 2022
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560por Mamaghani, Amirreza Javadi, Fathollahi, Anwar, Arab-Mazar, Zahra, kohansal, Kobra, Fathollahi, Matin, Spotin, Adel, Bashiri, Homayoon, Bozorgomid, Arezoo“…The antigens that have been proposed to be used in vaccine candidate in various studies include surface antigens and secretory excretions that have been synthesized and evaluated in different studies. …”
Publicado 2022
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