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901“…Although the simpler candidate-gene analysis technique is not considered cutting-edge, it is reliable and important to the translation of pharmacogenomic research and the advancement of precision medicine. …”
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902
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903“…In the present study, a transcriptome analysis of “Nantongxiaofangshi” was used to identify and clone 22 candidate genes related to gibberellin signal transduction pathways and synthetic pathway. …”
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904“…In this review, we will first present the currently used biomarkers and candidate biomarkers for the future. The current biomarkers are certainly very helpful including with the assistance of diagnostic method such the Roussel Uclaf Causality Assessment Method, but provide a limited information for the early detection of liver injury, the role of specific drug and the prediction of DILI. …”
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905
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906
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907por Voicu, Adrian, Duteanu, Narcis, Voicu, Mirela, Vlad, Daliborca, Dumitrascu, Victor“…Because only 5 molecules were included in the methotrexate cluster, we considered that they might have similar properties and might be further tested as potential drug candidates.…”
Publicado 2020
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908por Dick, ThomasEnlace del recurso
Publicado 2020
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909por Sussman, Robyn T., Rokita, Jo Lynne, Huang, Kevin, Raman, Pichai, Rathi, Komal S., Martinez, Daniel, Bosse, Kristopher R., Lane, Maria, Hart, Lori S., Bhatti, Tricia, Pawel, Bruce, Maris, John M.“…Together, these data demonstrate that CAMKV is a differentially-expressed cell surface protein that is transcriptionally regulated by MYCN, making it a candidate for targeting with antibodies or antibody-drug conjugates that do not cross the blood brain barrier.…”
Publicado 2020
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910por Saleem, Muhammad Hamzah, Ali, Shafaqat, Rehman, Muzammal, Hasanuzzaman, Mirza, Rizwan, Muhammad, Irshad, Sana, Shafiq, Fahad, Iqbal, Muhammad, Alharbi, Basmah M., Alnusaire, Taghreed S., Qari, Sameer H.Enlace del recurso
Publicado 2020
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911por Sastoque, Angie, Triana, Sergio, Ehemann, Kevin, Suarez, Lina, Restrepo, Silvia, Wösten, Han, de Cock, Hans, Fernández-Niño, Miguel, González Barrios, Andrés Fernando, Celis Ramírez, Adriana MarcelaEnlace del recurso
Publicado 2020
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912
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913por Zhang, Lyna, Katz, Jacqueline M., Gwinn, Marta, Dowling, Nicole F., Khoury, Muin J.“…We propose a list of approximately 100 systems-based candidate genes for future study of the genetic basis of influenza disease and immunity in humans, based on evidence in the published literature for their potential role in the pathogenesis of this infection: binding of the virus to receptors on the host cell surface; cleavability of HA by host proteases; virus replication in host cells; destruction of host cells by apoptosis; state of immunocompetence of the individual host; and viral infections predisposing to bacterial infection.…”
Publicado 2009
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914por Modjarrad, Kayvon“…Despite the relatively few number of cases to-date, research and development of MERS-CoV vaccine candidates is advancing quickly. This review surveys the landscape of these efforts across multiple groups in academia, government and industry.…”
Publicado 2016
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915por Liu, Shih-Jen, Leng, Chih-Hsiang, Lien, Shu-pei, Chi, Hsiang-Yun, Huang, Chiung-Yi, Lin, Chang-Ling, Lian, Wei-Cheng, Chen, Chi-Ju, Hsieh, Shie-Liang, Chong, PeleEnlace del recurso
Publicado 2006
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917por Abo-Ghalia, Mohamed H., Moustafa, Gaber O., Amr, Abd El-Galil E., Naglah, Ahmed M., Elsayed, Elsayed A., Bakheit, Ahmed H.Enlace del recurso
Publicado 2020
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918por Gao, Qiang, Bao, Linlin, Mao, Haiyan, Wang, Lin, Xu, Kangwei, Yang, Minnan, Li, Yajing, Zhu, Ling, Wang, Nan, Lv, Zhe, Gao, Hong, Ge, Xiaoqin, Kan, Biao, Hu, Yaling, Liu, Jiangning, Cai, Fang, Jiang, Deyu, Yin, Yanhui, Qin, Chengfeng, Li, Jing, Gong, Xuejie, Lou, Xiuyu, Shi, Wen, Wu, Dongdong, Zhang, Hengming, Zhu, Lang, Deng, Wei, Li, Yurong, Lu, Jinxing, Li, Changgui, Wang, Xiangxi, Yin, Weidong, Zhang, Yanjun, Qin, Chuan“…Here we developed a pilot-scale production of a purified inactivated SARS-CoV-2 virus vaccine candidate (PiCoVacc), which induced SARS-CoV-2-specific neutralizing antibodies in mice, rats and non-human primates. …”
Publicado 2020
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919
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920