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  1. 131201
    “…This is the first comprehensive and detailed study of Serratella diversity in China, which provides valuable information and character candidates to identify the genus and helps understand its phylogenetic position in the family. …”
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    A Review of the Genus Serratella Edmunds, 1959 in China with Description of a New Species (Ephemeroptera: Ephemerellidae) †
  2. 131202
    “…The first FCNN is trained to be more sensitive revealing possible candidate new lesion voxels, while the second FCNN is trained to reduce the number of misclassified voxels coming from the first network. 3D T2-FLAIR images from the two-time points were pre-processed and linearly co-registered. …”
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    Improving the detection of new lesions in multiple sclerosis with a cascaded 3D fully convolutional neural network approach
  3. 131203
    “…In conclusion, in this study we were able to identify several prognostic and predictive biomarker candidates in patients diagnosed of resectable or BL PDAC.…”
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    Cytokines and Lymphoid Populations as Potential Biomarkers in Locally and Borderline Pancreatic Adenocarcinoma
  4. 131204
    “…In addition to promoting somatic growth, this study also indicated that SDPP, especially in the current low fish meal diets, seems to be useful and beneficial at the immunological level and mucosal health status, which makes it a good candidate for incorporation into the aquaculture sector. …”
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    Evaluating the Functional Properties of Spray-Dried Porcine Plasma in Gilthead Seabream (Sparus aurata) Fed Low Fish Meal Diets
  5. 131205
    “…In summary, the BsAb YG-003D3 has good anti-tumor activity, which is expected to become a novel drug candidate for cancer immunotherapy.…”
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    PD-1/LAG-3 bispecific antibody potentiates T cell activation and increases antitumor efficacy
  6. 131206
    “…In this study, hsa‐miR‐370‐3p was screened as candidate miRNA targeting Snail and Twist1, and its expression was downregulated by IL‐8. …”
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    Hsa‐microRNA‐370‐3p targeting Snail and Twist1 suppresses IL‐8/STAT3‐driven hepatocellular carcinoma metastasis
  7. 131207
    “…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected human bronchial epithelial (HBE) cultures were used to investigate mechanisms of SARS-CoV-2–induced mucin expression and synthesis and test candidate countermeasures. MEASUREMENTS AND MAIN RESULTS: MUC5B and variably MUC5AC RNA concentrations were increased throughout all airway regions of COVID-19 autopsy lungs, notably in the subacute/chronic disease phase after SARS-CoV-2 clearance. …”
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    Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease
  8. 131208
    “…Overall, NOMAc is likely to be a promising candidate drug for ameliorating cancer cachexia induced by cisplatin.…”
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    Nomegestrol acetate ameliorated adipose atrophy in a rat model of cisplatin‑induced cachexia
  9. 131209
    “…Finally, the CMap database was used to predict candidate small compounds as prospective AVC therapeutics. …”
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    Development and analysis of a comprehensive diagnostic model for aortic valve calcification using machine learning methods and artificial neural networks
  10. 131210
    “…Covariates with p< 0.2 in univariate analyses were entered as candidate variables for stepwise selections. RESULTS: Among the 530 newly diagnosed PWH, mean age was 35, 79% were male, 46% non-Hispanic Black, 37% Hispanic. …”
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    1391. Association between Substance Abuse and Mental Illness Symptoms Screener (SAMISS) scores and HIV care cascade outcomes in newly diagnosed people with HIV (PWH) in the US South
  11. 131211
    “…Overall, the two highest performing candidates for further evaluation for varietal release were P5N05#10 and P2N09#12.…”
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    Improvement in cowpea variety Videza for traits of extra earliness and higher seed yield
  12. 131212
    “…Only designs with type I error between 0.05 and 0.1 and power of at least 0.8 were considered when selecting an optimal efficiency design from among the candidate designs formed by different combinations of posterior and predictive threshold. …”
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    Optimal predictive probability designs for randomized biomarker-guided oncology trials
  13. 131213
    “…The clinical significance of candidate hub gene was evaluated in 264 clinical samples and potential functions were validated in vitro and in vivo. …”
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    Interaction between glycolysis‒cholesterol synthesis axis and tumor microenvironment reveal that gamma-glutamyl hydrolase suppresses glycolysis in colon cancer
  14. 131214
    “…Machine learning (ML) algorithms have the potential to be a non-invasive way for identifying appropriate candidates for non-operative therapy. However, these ML models' interpretability remains challenging. …”
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    Interpretable machine learning for predicting pathologic complete response in patients treated with chemoradiation therapy for rectal adenocarcinoma
  15. 131215
    “…Lastly, we identified 11 promising APP lead candidates by using our best mQSSMs together with diversity-based network analyses, and 24 web servers for activity/toxicity and drug-like properties. …”
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    Network Science and Group Fusion Similarity-Based Searching to Explore the Chemical Space of Antiparasitic Peptides
  16. 131216
    “…Additionally, ATAC-seq experiments revealed that STAT3 binding motifs were preferentially enriched in open chromatin regions of the OSM-STAT3-regulated genes. Among the 50 candidate genes that were regulated epigenetically through the OSM-STAT3 axis, we found that the expression levels of NDRG1, HK2, PLOD2, and NPC1 were significantly correlated with those of OSMR and STAT3 in three independent cervical cancer cohorts. …”
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    Activation of OSM-STAT3 Epigenetically Regulates Tumor-Promoting Transcriptional Programs in Cervical Cancer
  17. 131217
    “…PICs can be easily sourced from skeletal muscle and therefore show promise as a potential cell candidate for supporting the reparative and regenerative effects of cell therapies.…”
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    Transplantation of Skeletal Muscle-Derived Sca-1(+)/PW1(+)/Pax7(−) Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction
  18. 131218
    “…Patients with lymph-node metastases or positive surgical margins (R1) were candidates for adjuvant treatment. Clinicopathological and survival data were retrieved from an institutional database. …”
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    The Prognostic Role of True Radical Resection in Perihilar Cholangiocarcinoma after Improved Evaluation of Radial Margin Status
  19. 131219
    “…Taken together, these results suggest that the BC02 compound adjuvant offers a strategy to induce an appropriate innate and adaptive immunity against the different doses of the VZV gE protein to improve subunit vaccine efficacy, and BC02 may be a promising adjuvant candidate for subunit HZ vaccines.…”
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    Novel BC02 Compound Adjuvant Enhances Adaptive and Innate Immunity Induced by Recombinant Glycoprotein E of Varicella-Zoster Virus
  20. 131220
    “…For the general control of emerging infectious diseases, establishing an efficient method to evaluate candidate therapeutic agents will lead to a rapid response. …”
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    Relationship between the inclusion/exclusion criteria and sample size in randomized controlled trials for SARS-CoV-2 entry inhibitors
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