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  1. 131341
    “…Cross-trait meta-analysis identified one candidate causal variant (rs1047891) underlying migraine, CKD, and kidney function. …”
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    Migraine, chronic kidney disease and kidney function: observational and genetic analyses
  2. 131342
    “…In-hospital mortality (1.45 (1.02 to 2.06)), discharge to a nursing facility (1.31 (1.03 to 1.66)), and delayed candidate arrival ≥2-hour of intravenous rt-PA (2.04 (1.30 to 3.26)) and endovascular reperfusion therapy (2.27 (1.06 to 5.00)), were more likely to be observed in the deprived areas with higher ADI. …”
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    Impact of areal socioeconomic status on prehospital delay of acute ischaemic stroke: retrospective cohort study from a prefecture-wide survey in Japan
  3. 131343
    “…It suggests that QBD and ART B are promising drug candidates for NSCLC treatment.…”
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    Integrating Network Pharmacology and Experimental Validation to Explore the Effects and Mechanisms of Qinghao Biejia Decoction and Its Active Compound Artemisinin B Against Non-Small-Cell Lung Cancer
  4. 131344
    “…METHODS: We collected the patient’s basic information, clinical data, as well as diagnostic and therapeutic history and performed whole-exome sequencing on her peripheral blood. Candidate pathogenic variants were validated by Sanger sequencing in family members, and the pathogenicity of variants was analyzed using ACMG guidelines. …”
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    Identification of compound heterozygous variants in MSH4 as a novel genetic cause of diminished ovarian reserve
  5. 131345
    “…People who use drugs (PWUD) are at increased risk of death by suicide relative to the general population, but there is a lack of information on associated candidate factors for suicide in this group. The aim of this study was to provide a comprehensive overview of existing evidence on potential factors for death by suicide in PWUD. …”
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    Factors associated with suicide in people who use drugs: a scoping review
  6. 131346
    “…From our study, Osa-MIR2919, Osa-MIR3979, Osa-MIR528, Osa-MIR2091-5p and Chr01_11911S14Astr and their target genes LOC_Os01g72000, LOC_Os01g66890, LOC_Os01g57990, LOC_Os01g56780, LOC_Os01g72834, LOC_Os01g61880 and LOC_Os01g72780 were identified as the most promising candidates for drought tolerance at booting stage. Of these, Osa-MIR2919 with 19 target genes in the qDTYs is being reported for the first time. …”
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    Integration of miRNA dynamics and drought tolerant QTLs in rice reveals the role of miR2919 in drought stress response
  7. 131347
    “…CONCLUSIONS: The ESR may be useful to improve the ultrasound evaluation of the endometrial quality in infertile women candidates to IVF/ICS. Given the small sample size of our study, the usefulness of strain elastosonography in this patients, needs further investigation. …”
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    The use of real time strain endometrial elastosonography plus endometrial thickness and vascularization flow index to predict endometrial receptivity in IVF treatments: a pilot study
  8. 131348
    “…GSCs’ physio-pathological hallmarks were delineated by comparing over time in vitro and in vivo their expansion, self-renewal and tumorigenic ability with hierarchical linear models for repeated measurements and Kaplan–Meier method. Candidate biomarkers performance in discriminating GBM patients’ classification emerged by classification tree and patients’ survival analysis. …”
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    Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies
  9. 131349
    “…The U-Net, U-Net +  + , DeepLabV3, DeepLabV3Plus, Transunet, and Segformer were used as candidate model architectures, and each of the first four architectures adopted two different encoders choosing from resnet34, resnet50 and denseNet121. …”
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    Automated cervical cell segmentation using deep ensemble learning
  10. 131350
    “…Furthermore, selective sweep analysis revealed candidate genes which were associated with specific and common phenotypic characteristics evolved rapidly after domestication of Guizhou local chicken breeds and economic traits such as egg production performance, growth performance, and body size. …”
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    Whole-genome sequencing revealed genetic diversity, structure and patterns of selection in Guizhou indigenous chickens
  11. 131351
    “…Logistic regression is applied to calculate the odds ratio (OR) of candidate variables. The α level was set at 0.05. RESULTS: Among patients under the age of 50, the percentage of females in URVNA was 55.05%, while in URVA it was 53.25%. …”
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    The risk factors of the 72-h unscheduled return visit admission to emergency department in adults below 50 years old
  12. 131352
    “…Thus, the findings of this study strongly imply that the Cm-AgNPs can serve as promising candidates for therapeutic applications, especially against multidrug-resistant isolates of Candida and bacteria. …”
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    Antimicrobial and antioxidant potential of the silver nanoparticles synthesized using aqueous extracts of coconut meat (Cocos nucifera L)
  13. 131353
    “…In conclusion, the high-affinity anti-PD-1 antibody developed in this study represents a powerful tool for detecting and inhibiting bovine PD-1 and is a candidate for PD-1-targeted immunotherapy in cattle. …”
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    Development of a high-affinity anti-bovine PD-1 rabbit–bovine chimeric antibody using an efficient selection and large production system
  14. 131354
    “…The results show that, the ZnO/Cu-DPA nano-catalyst is a potential candidate for the remediation of dirty water.…”
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    Highly efficient visible light active ZnO/Cu-DPA composite photocatalysts for the treatment of wastewater contaminated with organic dye
  15. 131355
    “…Gene expression in the intima-media of the ascending aorta was measured in 22 patients with non-dilated and 24 with dilated aortas, and candidate genes were identified. Protein expression was assessed using immunohistochemistry. …”
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    SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
  16. 131356
    “…Furthermore, 28 novel ASD candidate genes were identified in 20 families, 23 of which had recurrent hits in MSSNG and SSC cohorts. …”
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    Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
  17. 131357
    “…Furthermore, comparisons between our data and transcriptome data from other species suggest that the suppression of outgrowth of bud 2 was correlated with a limited supply of carbon to these axillary buds. Candidate genes that might repress bud outgrowth were identified by co-expression analysis. …”
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    Transcriptomic analysis implicates ABA signaling and carbon supply in the differential outgrowth of petunia axillary buds
  18. 131358
    “…BACKGROUND: The Nutri-Score is a candidate for the harmonized mandatory front-of-pack nutrition label enabling consumers in the European Union to make healthier food choices. …”
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    How does the updated Nutri-Score discriminate and classify the nutritional quality of foods in a Norwegian setting?
  19. 131359
    “…QL-1200186 could be an appealing clinical drug candidate for the treatment of psoriasis and other autoimmune diseases. …”
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    A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathways
  20. 131360
    “…RESULTS: We prioritized a top candidate histone acetyltransferase, CSRP2BP, as a key player in cervical cancer EMT and metastasis. …”
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    Histone acetyltransferase CSRP2BP promotes the epithelial–mesenchymal transition and metastasis of cervical cancer cells by activating N-cadherin
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