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131601por Lo, Kuan-Lin, Chen, Yi-Nian, Chiang, Min-Yu, Chen, Mei-Chun, Panibe, Jerome P., Chiu, Chung-Chun, Liu, Lu-Wei, Chen, Liang-Jwu, Chen, Chun-Wei, Li, Wen-Hsiung, Wang, Chang-Sheng“…Sequence analysis and genomic editing study revealed 2 and 7 candidate R genes in Pi169-6(t) and Pi169-11(t), respectively. …”
Publicado 2022
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131602por Nickerson, Aidan P., Corbin, Laura J., Timpson, Nicholas J., Phillips, Keith, Pickering, Anthony E., Dunham, James P.“…We propose an adaptive methodology within a recall-by-genotype (RbG) framework using detailed phenotyping to screen minor alleles in a candidate ‘nociceptor’ gene in an attempt to estimate their genetic contribution to pain. …”
Publicado 2022
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131603por Zhu, Zhixing, Lian, Xihua, Su, Xiaoshan, Wu, Weijing, Zeng, Yiming, Chen, Xiaoyang“…Therefore, hADSCs-Exo may be a promising cell-free therapeutic candidate for CS-induced lung inflammation and injury. …”
Publicado 2022
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131604por de Almeida Baptista, Marcella Vassão, da Silva, Laís Teodoro, Samer, Sadia, Oshiro, Telma Miyuki, Shytaj, Iart Luca, Giron, Leila B., Pena, Nathalia Mantovani, Cruz, Nicolly, Gosuen, Gisele Cristina, Ferreira, Paulo Roberto Abrão, Cunha-Neto, Edécio, Galinskas, Juliana, Dias, Danilo, Sucupira, Maria Cecilia Araripe, de Almeida-Neto, Cesar, Salomão, Reinaldo, da Silva Duarte, Alberto José, Janini, Luís Mário, Hunter, James R., Savarino, Andrea, Juliano, Maria Aparecida, Diaz, Ricardo Sobhie“…Moreover, intracellular TNF and IFN-γ expression was significantly increased in CD4(+) T-cells. The number of candidates that increased in vitro the cytokine levels in CD4(+) and CD8(+) T cells upon stimulation with Gag peptides from baseline to day 15 and from baseline to day 30 and day 120 after MDDCT was significant as compared to Gag unstimulated response. …”
Publicado 2022
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131605por Banitalebi, Hasan, Espeland, Ansgar, Anvar, Masoud, Hermansen, Erland, Hellum, Christian, Brox, Jens Ivar, Myklebust, Tor Åge, Indrekvam, Kari, Brisby, Helena, Weber, Clemens, Aaen, Jørn, Austevoll, Ivar Magne, Grundnes, Oliver, Negård, Anne“…METHODS: Consecutive lumbar MRI examinations of candidates for surgical treatment of LSS from the Norwegian Spinal Stenosis and Degenerative Spondylolisthesis (NORDSTEN) study were independently evaluated by two musculoskeletal radiologists and two orthopaedic spine surgeons. …”
Publicado 2022
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131606por Yuan, Tao, He, Hongyu, Liu, Yuepeng, Wang, Jianwei, Kang, Xin, Fu, Guanghui, Xie, Fangfang, Li, Aimin, Chen, Jun, Wang, Wenxue“…Information on the disease, laboratory examination, insulin therapy, and surgery for patients with TBI was collected as candidate variables according to clinical importance. …”
Publicado 2022
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131607“…However, in MT3 which secrets brochosomes to the integument and eggs as physical barriers, disulfide-isomerase, acidic ribosomal protein P and many other unigenes were highly expressed, which can be attractive candidate genes for future studies of the biosynthesis and the origin of brochosomes. …”
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131608por Jacobs, Sarah M., Wesseling, Pieter, de Keizer, Bart, Tolboom, Nelleke, Ververs, F. F. Tessa, Krijger, Gerard C., Westerman, Bart A., Snijders, Tom J., Robe, Pierre A., van der Kolk, Anja G.“…However, when high CXCR4 expression can be identified with [(68)Ga]Ga-Pentixafor, these patients might be good candidates for targeted radionuclide therapy with [(177)Lu]Lu-Pentixather in the future. …”
Publicado 2021
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131609por Teshager, Nahom Worku, Amare, Ashenafi Tazebew, Tamirat, Koku Sisay, Zemene, Melkamu Aderajew“…A p-value of less than 0.2 was used to select candidate variables for multivariable analysis. A binary logistic regression model was fitted to identify factors associated with wasting. …”
Publicado 2022
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131610por Ilangovan, Kumaravel, Muthappan, Sendhilkumar, Govindarajan, Keerthiga, Vairamani, Vignesh, Venkatasamy, Vettrichelvan, Ponnaiah, Manickam“…These programmes stated that they admit candidates of but not limited to “graduation in any life sciences”, “3-year bachelor’s degree in any discipline”, “graduation from any Indian universities”, and “graduation in any discipline”. …”
Publicado 2022
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131611por Gorbenko, Oleks, Cavillon, Pascale, Giles, Rachel H., Kolarova, Teodora, Marks, Muriël, Cardone, Antonella, Bagga, Sandeep, Nolan, Claire“…METHODS: Semi-structured interviews were conducted with 13 patient organisation (PO) representatives exploring their experiences of engagement and reflections on 23 candidate patient engagement impact measures categorised into five groups: Medicines R&D Priorities; Clinical Trial Design; Regulatory & Market Access Submissions; Product Support & Information; and Disease Support & Information. …”
Publicado 2022
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131612por Ravelombola, Waltram, Shi, Ainong, Huynh, Bao-Lam, Qin, Jun, Xiong, Haizheng, Manley, Aurora, Dong, Lingdi, Olaoye, Dotun, Bhattarai, Gehendra, Zia, Bazgha, Alshaya, Huda, Alatawi, Ibtisam“…RESULTS: Results indicated that: (1) large variation in traits evaluated for salt tolerance was identified among the MAGIC lines, (2) a total of 7, 2, 18, 18, 3, 2, 5, 1, and 23 were associated with number of dead plants, salt injury score, leaf SPAD chlorophyll under salt treatment, relative tolerance index for leaf SPAD chlorophyll, fresh leaf biomass under salt treatment, relative tolerance index for fresh leaf biomass, relative tolerance index for fresh stem biomass, relative tolerance index for the total above-ground fresh biomass, and relative tolerance index for plant height, respectively, with overlapping SNP markers between traits, (3) candidate genes encoding for proteins involved in ion transport such as Na+/Ca2+ K+ independent exchanger and H+/oligopeptide symporter were identified, and (4) epistatic interactions were identified. …”
Publicado 2022
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131613por Schmitz, Alexander, Brøndum, Rasmus Froberg, Johnsen, Hans Erik, Mellqvist, Ulf-Henrik, Waage, Anders, Gimsing, Peter, op Bruinink, Davine Hofste, van der Velden, Vincent, van der Holt, Bronno, Hansson, Markus, Andersen, Niels Frost, Frølund, Ulf Christian, Helleberg, Carsten, Schjesvold, Fredrik H., Ahlberg, Lucia, Gulbrandsen, Nina, Andreasson, Bjorn, Lauri, Birgitta, Haukas, Einar, Bødker, Julie Støve, Roug, Anne Stidsholt, Bøgsted, Martin, Severinsen, Marianne T., Gregersen, Henrik, Abildgaard, Niels, Sonneveld, Pieter, Dybkær, Karen“…However, for multiple myeloma, it is unclear whether patients attaining minimal residual disease negativity may be candidates for treatment discontinuation. We investigated, if longitudinal flow cytometry-based monitoring of minimal residual disease (flow-MRD) may predict disease progression earlier and with higher sensitivity compared to biochemical assessments. …”
Publicado 2022
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131614por Passardi, Alessandro, Foca, Flavia, Caffo, Orazio, Tondini, Carlo Alberto, Zambelli, Alberto, Vespignani, Roberto, Bartolini, Giulia, Sullo, Francesco Giulio, Andreis, Daniele, Dianti, Marco, Eccher, Claudio, Piras, Enrico Maria, Forti, Stefano“…METHODS: Patients aged ≥18 years who were candidates for oral anticancer treatment as monotherapy with an Eastern Cooperative Oncology Group performance status score of 0 to 1 and a sufficient level of familiarity with mobile devices were eligible. …”
Publicado 2022
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131615por Kalaiselvi, S. M. P., Tang, E. X., Moser, H. O., Breese, M. B. H., Turaga, S. P., Kasi, H., Heussler, S. P.“…Due to its parallel processing capability, our methodology serves as a promising candidate to fabricate micro/nano components of optical quality on a large scale to cater for industrial requirements. …”
Publicado 2022
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131616por Balogh, Olivér M., Benczik, Bettina, Horváth, András, Pétervári, Mátyás, Csermely, Péter, Ferdinandy, Péter, Ágg, Bence“…BACKGROUND: The investigation of possible interactions between two proteins in intracellular signaling is an expensive and laborious procedure in the wet-lab, therefore, several in silico approaches have been implemented to narrow down the candidates for future experimental validations. Reformulating the problem in the field of network theory, the set of proteins can be represented as the nodes of a network, while the interactions between them as the edges. …”
Publicado 2022
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131617por Li, Xintong, Wen, Hao, Lv, Junyuan, Luan, Boyang, Meng, Jinze, Gong, Shiqiang, Wen, Jie, Xin, Shijie“…These results are important for the systemic application of MSCs as a potential treatment candidate for AAA in further animal experiments and clinical trials. …”
Publicado 2022
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131618por Pohl, Carsten, Schmidt, Bertram, Nunez Guitar, Tamara, Klemm, Sophie, Gusovius, Hans-Jörg, Platzk, Stefan, Kruggel-Emden, Harald, Klunker, Andre, Völlmecke, Christina, Fleck, Claudia, Meyer, Vera“…The ability of many basidiomycetes to accept residual lignocellulosic plant biomass from agriculture and forestry such as straw, shives and sawdust as substrates and to bind and glue together these otherwise loose but reinforcing substrate particles into their mycelial network, makes them ideal candidates to produce biological composites to replace petroleum-based synthetic plastics and foams in the near future. …”
Publicado 2022
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131619por Mæland, Silje, Holmås, Tor Helge, Øyeflaten, Irene, Husabø, Elisabeth, Werner, Erik L., Monstad, Karin“…METHODS: This was a pragmatic randomised controlled trial including all employees aged 18–65 years, sick-listed by their general practitioner and on full or partial sick leave for the past 26 weeks in Hordaland County, Norway in 2015/16. Trial candidates were drawn from a central register at the Norwegian Labour and Welfare Administration at 22 weeks of sick leave. …”
Publicado 2022
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131620por Chaniad, Prapaporn, Phuwajaroanpong, Arisara, Techarang, Tachpon, Horata, Natharinee, Chukaew, Arnon, Punsawad, Chuchard“…CONCLUSION: This study demonstrates that M. fragrans is a potential candidate for the development of antimalarial agents.…”
Publicado 2022
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