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  1. 131781
    “…Several plant-derived natural biomolecules have been recently used to reduce the toxic effects of Al through decreasing the oxidative stress and the associated diseases. A good candidate still to be tested is an active natural furanocoumarin, the isoimperatorin (IMP) that can be extracted from Lemon and lime oils and other plants. …”
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    Isoimperatorin therapeutic effect against aluminum induced neurotoxicity in albino mice
  2. 131782
    “…Patients with the longest survival were also the best candidates for repeated surgery. Later recurrence of glioblastoma was associated with higher survival rates after reoperation.…”
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    Effects of Reoperation Timing on Survival among Recurrent Glioblastoma Patients: A Retrospective Multicentric Descriptive Study
  3. 131783
    “…This study provides novel information about effects of two M. truncatula growth-promoting rhizobacteria strains and suggests that both have a potential to be candidates for PGPR inoculant products on account of their ability to inhibit in vitro growth of Fusarium directly and indirectly by up-regulation of some defense priming markers such as CHIT, GLU and PAL genes in plants. …”
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    Two Medicago truncatula growth-promoting rhizobacteria capable of limiting in vitro growth of the Fusarium soil-borne pathogens modulate defense genes expression
  4. 131784
    “…Patients who receive treatment with curative intent but are poor candidates for or decline surgery receive definitive bimodality therapy. …”
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    ‘CROSS’-ing into the ‘Real World’: a retrospective cohort study of patients receiving trimodality and bimodality therapy for esophageal cancer
  5. 131785
    por Song, J.Y., Choi, W.S., Cheong, H.J., Kim, H.
    Publicado 2023
    “…We report interim Phase 3 study (NCT05007951) results up to 4 weeks post-dose 2 (Data-cut: March-18-2022), where immunogenicity to the D614G ancestral strain and safety of 25μg GBP510/AS03 candidate was compared to ChAdOx1-S (Vaxzevria). METHODS: This Phase 3 randomized, active-controlled, observer-blind, parallel- group study in adults was conducted in 6 countries. …”
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    PHASE 3 STUDY OF SAFETY AND IMMUNOGENICITY OF GBP510 VACCINE ADJUVANTED WITH AS03 IN ADULTS
  6. 131786
    “…These findings suggest that children with co-occurring delays may be potential candidates for community assessment.…”
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    Concordance of Diagnosis of Autism Spectrum Disorder Made by Pediatricians vs a Multidisciplinary Specialist Team
  7. 131787
    “…The effect of potential candidate cytokines on fatty acid metabolism in ex vivo placental explants culture following C-section a term was also examined. …”
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    Maternal elevated inflammation impairs placental fatty acids β-oxidation in women with gestational diabetes mellitus
  8. 131788
    por Li, Youjun, Li, Xiaobo, Yu, Zhengtao
    Publicado 2023
    “…We found that GSEC could serve as a candidate methylation marker and a prognostic risk factor for overall survival in low-grade glioma patients. …”
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    Novel methylation-related long non-coding RNA clinical outcome prediction method: the clinical phenotype and immune infiltration research in low-grade gliomas
  9. 131789
    “…CONCLUSION: Based on our results, CRT candidates are exceedingly vulnerable with a high prevalence of frailty. …”
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    The prevalence and importance of frailty in cardiac resynchronization therapy patients
  10. 131790
    “…A genome-wide association study detected six candidate single nucleotide polymorphisms (SNPs) as predictors for milk production in heat-stressed Holstein cows. …”
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    Genetic Markers Associated with Milk Production and Thermotolerance in Holstein Dairy Cows Managed in a Heat-Stressed Environment
  11. 131791
    “…Thirty-five DEGs were involved in the lipid metabolic process, which might be candidate genes regulating the lipogenesis of chicken. …”
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    Integrated Metabolomic and Transcriptomic Analysis Reveals Potential Gut-Liver Crosstalks in the Lipogenesis of Chicken
  12. 131792
    “…The survey included questions on media sources for COVID-19 information, political affiliation, presidential candidate choice, and multiple Likert-type agreement scale questions on conceptions of the vaccine. …”
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    The Influence of Mass Media on the COVID-19 Vaccination Decision-making Process: Prospective Survey-Based Study
  13. 131793
    “…METHODS: Fifteen non-diabetic subjects, candidates for anti-PCSK9 mAb therapy, were enrolled. …”
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    Effects of PCSK9 inhibition on glucose metabolism and β-cell function in humans: a pilot study
  14. 131794
    “…In conclusion, we isolated three phages that can infect P. aeruginosa, which were stable in different environments and could reduce bacterial biofilms, suggesting their potential as promising candidates to treat P. aeruginosa infections. IMPORTANCE Phage therapy is a promising therapeutic option for treating bacterial infections that do not respond to common antimicrobial treatments. …”
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    Isolation and Characterization of Three Pseudomonas aeruginosa Viruses with Therapeutic Potential
  15. 131795
    “…Our findings suggest that the rS1Beta subunit vaccine candidate as a booster has the potential to offer cross-neutralization against broad variants and has important implications for the vaccine control of newly emerging breakthrough SARS-CoV-2 variants in elderly individuals primed with adenovirus-based vaccines like AZD1222 and Ad26.COV2.S. …”
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    SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice
  16. 131796
    “…Our findings indicate persistent Th17-driven inflammation in the CSF, possibly contributing to a longer convalescence, and suggest IL-17A and CCL20 as potential biomarker candidates for patients with LNB.…”
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    Intrathecal Th17-driven inflammation is associated with prolonged post-treatment convalescence for patients with Lyme neuroborreliosis
  17. 131797
    “…CONCLUSION: In summary, we demonstrate that multi-targeted cfDNA analysis, using a combination of SNVs/indels and SVs candidates identified by WGS analysis, provides a sensitive tool for MRD monitoring and can detect lymphoma relapse earlier than clinical manifestation.…”
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    Whole-genome informed circulating tumor DNA analysis by multiplex digital PCR for disease monitoring in B-cell lymphomas: a proof-of-concept study
  18. 131798
    “…Using the annotation information of IWGSC Chinese Spring RefSeq v1.1 genome assembly, we predicted 28 and 69 candidate genes for major loci from QTL mapping and GWAS, respectively. …”
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    Genetic dissection of protein and starch during wheat grain development using QTL mapping and GWAS
  19. 131799
    “…We aimed to expand the immunological tool kit against HNSCC by conducting a functional screen to generate chimeric antigen receptor (CAR)-NK-92 cells that target HER1/epidermal growth factor receptor (EGFR). (2) Methods: Selected CAR-NK-92 cell candidates were tested for enhanced reduction of target cells, CD107a expression and IFNγ secretion in different co-culture models. …”
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    CAR-NK Cells Targeting HER1 (EGFR) Show Efficient Anti-Tumor Activity against Head and Neck Squamous Cell Carcinoma (HNSCC)
  20. 131800
    “…Thus, H. sabdariffa methanol extract is a promising candidate to be further investigated for developing alternative natural therapies for infection treatment.…”
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    GC-MS Analysis, Antibacterial, and Anticancer Activities of Hibiscus sabdariffa L. Methanolic Extract: In Vitro and In Silico Studies
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