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  1. 131801
    “…Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. …”
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    Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
  2. 131802
    “…Diversity indices were estimated using DnaSP (v.6) while phylogenetic analysis was inferred using the Bayesian method using MrBayes (v.1.1). β-tubulin gene isoforms sequence analysis was performed to find out the candidate gene causing benzimidazole resistance. All 40 isolates were found positive for E. granulosus. …”
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    Revealing novel cytb and nad5 genes-based population diversity and benzimidazole resistance in Echinococcus granulosus of bovine origin
  3. 131803
    “…We suggest that the diagnostic rate for hereditary ataxia could be increased by removing the age-of-onset partition, and through a modified screening for repeat expansions in naturally-occurring STRs within known ataxia-associated genes, in effect treating these regions as candidate pathogenic loci.…”
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    Functional genomics provide key insights to improve the diagnostic yield of hereditary ataxia
  4. 131804
    “…After LASSO analysis, 12 HUB genes were chosen as candidate biomarkers for LUAD expression. According to the immune infiltration results, CD4 + T cells, B cells, and NK cells were high in LUAD sample tissue. …”
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    Comprehensive analysis to identify a novel diagnostic marker of lung adenocarcinoma and its immune infiltration landscape
  5. 131805
    “…The decrease in retinal vascular fractal dimension and decreased vascular density may serve as candidate biomarkers for early identification of cognitive impairment. …”
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    Relationships between quantitative retinal microvascular characteristics and cognitive function based on automated artificial intelligence measurements
  6. 131806
    “…Moderate to high-risk candidates were screened for NeoChord DS1000 eligibility based on echocardiographic criteria. …”
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    Echocardiographic and clinical outcomes following beating heart NeoChord DS1000 mitral valve repair: a single centre case series
  7. 131807
    “…Simple-choice questions are primarily knowledge-based and multiple-choice, whereas situation-setup questions entail the candidate reading a patient’s and family situation’s description, and selecting the nurse's action or patient's response. …”
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    Performance of the Large Language Model ChatGPT on the National Nurse Examinations in Japan: Evaluation Study
  8. 131808
    “…SIMPLE SUMMARY: Patients with early-stage BCLC 0/A hepatocellular carcinoma (HCC) who are not candidates for liver transplantation or resection are treated with percutaneous ablation according to guidelines. …”
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    Risk of Treatment Failure and Death after Ablation in Hepatocellular Carcinoma Patients—A Multiparametric Prediction
  9. 131809
    “…Metachronous solitary or oligometastasis from RCC are considered the ideal candidates for target treatments, allowing the achievement of “non-evidence of disease” status. …”
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    The Impact of Metastasectomy on Survival Outcomes of Renal Cell Carcinoma: A 10-Year Single Center Experience
  10. 131810
    “…The KPF-enriched extract (KPF-ABR) showed an increased inhibitory effect on the cell migration and invasion, characterizing it as the best antitumor candidate.…”
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    Kaempferol and Biomodified Kaempferol from Sophora japonica Extract as Potential Sources of Anti-Cancer Polyphenolics against High Grade Glioma Cell Lines
  11. 131811
    “…Bivariable logistic regression was run to identify the candidate variables at p-value <0.25. Variables that had associations with latrine utilization in the bi-variable analysis were entered together into multivariable logistic regression. …”
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    Latrine utilization and associated factors among districts implementing and not-implementing community-led total sanitation and hygiene in East Wollega, Western Ethiopia: A comparative cross-sectional study
  12. 131812
    “…CONCLUSION: Our study offers a novel method for using the food‐grade, non‐pathogenic and noncommercial bacterium L. lactis as a protein cell factory to produce the novel immunogenic fusion candidate romp25. This method offers an appealing new approach to assessing the cost‐effective, safe, sustainable, simple pilot development of pharmaceutical products.…”
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    Brucella abortus antigen omp25 vaccines: Development and targeting based on Lactococcus lactis
  13. 131813
    “…Based on our predicted antigenicity and pathogenicity studies of the two BVDV serotypes, the sub-genotypes (1a, 1f, 1k, 2a, and 2b) may represent ideal candidates for the development of future vaccines against BVDV infection in cattle. …”
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    Immunoinformatic prediction of the pathogenicity of bovine viral diarrhea virus genotypes: implications for viral virulence determinants, designing novel diagnostic assays and vaccines development
  14. 131814
    “…Known genes most frequently implicated by polymicrogyria-associated variants in this cohort were PIK3R2, TUBB2B, COL4A1, and SCN3A. Six candidate novel polymicrogyria genes were identified or confirmed: de novo missense variants in PANX1, QRICH1, and SCN2A and compound heterozygous variants in TMEM161B, KIF26A, and MAN2C1, each with consistent genotype-phenotype relationships in multiple families. …”
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    Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria
  15. 131815
    “…These findings provide potential pan-sarbecovirus neutralizing drugs and highlight new pathways to rapidly optimize therapeutic candidates when novel SARS-CoV-2 escape variants or new zoonotic coronaviruses emerge. …”
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    Broad Sarbecovirus Neutralizing Antibodies Obtained by Computational Design and Synthetic Library Screening
  16. 131816
    “…Collectedly, our findings suggested the marked anti-inflammatory and anti-apoptotic activity of CBs which encouraged its use as a new candidate for septic patients.…”
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    Cepabiflas B and C as Novel Anti-Inflammatory and Anti-Apoptotic Agents against Endotoxin-Induced Acute Kidney and Hepatic Injury in Mice: Impact on Bax/Bcl2 and Nrf2/NF-κB Signalling Pathways
  17. 131817
    “…In addition to the more sensitive thyroid nodule screening technology, several social and environmental factors might represent credible candidates for this increase. They include psychological stress, lifestyle-associated risk factors, nutritional deficiencies, and environmental pollutants. …”
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    Associations of psychological status and ultrasonic characteristics of thyroid nodules in adults during the COVID-19 pandemic
  18. 131818
    “…METHODS: The muscle mass–based eGFR (MMB-eGFR) equation was developed in 118 kidney donor candidates (iohexol clearance) using linear regression. …”
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    Development and validation of a new equation based on plasma creatinine and muscle mass assessed by CT scan to estimate glomerular filtration rate: a cross-sectional study
  19. 131819
    “…METHODS: A retrospective explorative analysis was performed on SCI patients admitted to a tertiary academic medical center between January 2018 and June 2022. The candidate predictor variables, including demographics, clinical characteristics and complications, were analyzed with logistic and linear regression. …”
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    A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury
  20. 131820
    “…Cardiopulmonary rehabilitation is a mainstay of management of symptomatic post-COVID patients, and optimization of candidate selection might allow for more effective use of available resources. …”
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    Spontaneous physical functional recovery after hospitalization for COVID-19: insights from a 1 month follow-up and a model to predict poor trajectory
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