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132081por Wanji, Samuel, Kengne-Ouafo, Jonas A., Esum, Mathias E., Chounna, Patrick W. N., Adzemye, Bridget F., Eyong, Joan E. E., Jato, Isaac, Datchoua-Poutcheu, Fabrice R., Abong, Raphael A., Enyong, Peter, Taylor, David W.“…Parasitological examinations (skin sniping and nodule palpation) were done on eligible candidates. Parasitological indicators were calculated and correlated to IVM intake profile. …”
Publicado 2015
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132082por Luo, Gang, Stone, Bryan L, Sakaguchi, Farrant, Sheng, Xiaoming, Murtaugh, Maureen A“…If an existing model were used to identify candidate patients for case management, enrollment would miss more than half of those who would benefit most, but include others unlikely to benefit, wasting limited resources. …”
Publicado 2015
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132083por Cherif, Mariama, Amoako-Sakyi, Daniel, Dolo, Amagana, Pearson, Jan-Olov, Gyan, Ben, Obiri-Yeboah, Dorcas, Nebie, Issa, Sirima, Sodiomon B., Doumbo, Ogobara, Troye-Blomberg, Marita, Bakary, Maiga“…Studying genetic susceptibility to malaria is ideal among sympatric populations because the distribution of polymorphic genes among such populations can help in the identification malaria candidate genes. This study determined the distribution of three FcyRs single nucleotide polymorphisms (SNPs) (FcγRIIB-rs1050519, FcγRIIC-rs3933769 and FcγRIIIA-rs396991) among sympatric Fulani and Dogon children with uncomplicated malaria. …”
Publicado 2016
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132084por Wang, Fan, Lu, Juan, Peng, Xiaohong, Wang, Jie, Liu, Xiong, Chen, Xiaomei, Jiang, Yiqi, Li, Xiangping, Zhang, Bao“…The result was validated by real-time PCR on 201 NPC and 25 chronic nasopharyngitis patients. The potential candidate target genes of the miRNAs were predicted using published target prediction softwares (RNAhybrid, TargetScan, Miranda, PITA), and the overlay part was analyzed in Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) biological process. …”
Publicado 2016
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132085por Kawasaki, Masanori, Tanaka, Ryuhei, Miyake, Taiji, Matsuoka, Reiko, Kaneda, Mayumi, Minatoguchi, Shingo, Hirose, Takeshi, Ono, Koji, Nagaya, Maki, Sato, Hidemaro, Kawase, Yoshiaki, Tomita, Shinji, Tsuchiya, Kunihiko, Matsuo, Hitoshi, Noda, Toshiyuki, Minatoguchi, Shinya“…The ePCWP estimated by STE is useful to predict the successful ablation in paroxysmal AF, and could be useful to improve candidate selection for AF ablation.…”
Publicado 2016
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132086por Saad, Marc, Karam, Boutros, Faddoul, Geovani, Douaihy, Youssef El, Yacoub, Harout, Baydoun, Hassan, Boumitri, Christine, Barakat, Iskandar, Saifan, Chadi, El-Charabaty, Elie, Sayegh, Suzanne El“…Many observations have reported discrimination of care for patients with CKD considered suboptimal candidates for aggressive management of their cardiac disease. …”
Publicado 2016
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132087por Wang, Bi, Wang, Lanlan, Chen, Fangyuan, Yang, Xiuling, Ding, Ming, Zhang, Zhongkai, Liu, Shu-Sheng, Wang, Xiao-Wei, Zhou, Xueping“…BLASTn searches and sequence analysis identified 112 and 136 conserved miRNAs from nonviruliferous and viruliferous whitefly libraries respectively, and a comparison of the conserved miRNAs of viruliferous and nonviruliferous whiteflies revealed 15 up- and 9 down-regulated conserved miRNAs. 7 novel miRNA candidates with secondary pre-miRNA hairpin structures were also identified. …”
Publicado 2016
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132088por Ganeshan, Harini, Kusi, Kwadwo A., Anum, Dorothy, Hollingdale, Michael R., Peters, Bjoern, Kim, Yohan, Tetteh, John K. A., Ofori, Michael F., Gyan, Ben A., Koram, Kwadwo A., Huang, Jun, Belmonte, Maria, Banania, Jo Glenna, Dodoo, Daniel, Villasante, Eileen, Sedegah, Martha“…Identification of immunodominant T cell epitopes will assist in determining if candidate vaccines will be immunogenic in malaria-endemic areas. …”
Publicado 2016
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132089por Kim, Jong-Ho, Choi, Seung-Cheol, Park, Chi-Yeon, Park, Jae-Hyoung, Choi, Ji-Hyun, Joo, Hyung-Joon, Hong, Soon-Jun, Lim, Do-Sun“…Adipose-derived stem cells (ADSCs) have the potential to differentiate into various cell lineages and they are easily obtainable from patients, which makes them a promising candidate for cell therapy. However, a drawback is their limited life span during in vitro culture. …”
Publicado 2016
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132090por Jiang, Zhen-zhen, Liu, Yu-mei, Niu, Xin, Yin, Jian-yong, Hu, Bin, Guo, Shang-chun, Fan, Ying, Wang, Yang, Wang, Nian-song“…Stem cells are currently the main candidates for the development of new treatments for diabetic nephropathy, as they may exert their therapeutic effects mainly through paracrine mechanisms. …”
Publicado 2016
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132091por Matika, Oswald, Riggio, Valentina, Anselme-Moizan, Marie, Law, Andrew S., Pong-Wong, Ricardo, Archibald, Alan L., Bishop, Stephen C.“…We identified plausible positional candidate genes for these OAR6 QTL. We also detected a SNP that reached the genome-wide significance threshold with a p value of 7.28 × 10(−7) and was associated with muscle density on OAR1. …”
Publicado 2016
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132092por Singh, Ruby, Purkait, Bidyut, Abhishek, Kumar, Saini, Savita, Das, Sushmita, Verma, Sudha, Mandal, Abhishek, Ghosh, Ayan Kr., Ansari, Yousuf, Kumar, Ashish, Sardar, Abul H., Kumar, Ajay, Parrack, Pradeep, Das, Pradeep“…So, LdUMSBP may be an attractive target for rational drug designing and LdU(−/+) parasites could be considered as a live attenuated vaccine candidate against visceral leishmaniasis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13578-016-0072-z) contains supplementary material, which is available to authorized users.…”
Publicado 2016
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132093por Zhang, Shaojun, Yang, Wenzhu, Zhao, Qianqian, Zhou, Xiaojin, Jiang, Ling, Ma, Shuai, Liu, Xiaoqing, Li, Ye, Zhang, Chunyi, Fan, Yunliu, Chen, Rumei“…IP pools were found to be transported by specific ATP-binding cassette (ABC) transporters. Finally, three candidate genes (Mf3, DH2 and CB5) were identified and validated using Arabidopsis lines with mutations in orthologous genes or RNA interference (RNAi)-transgenic maize lines. …”
Publicado 2016
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132094por Baurley, James W., Edlund, Christopher K., Pardamean, Carissa I., Conti, David V., Bergen, Andrew W.“…This array allows researchers to perform genome-wide, candidate gene, and pathway-based association analyses of addiction, tobacco-use, treatment response, comorbidities, and associated diseases in a standardized, high-throughput platform. …”
Publicado 2016
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132095por Holm, Karolina, Staaf, Johan, Lauss, Martin, Aine, Mattias, Lindgren, David, Bendahl, Pär-Ola, Vallon-Christersson, Johan, Barkardottir, Rosa Bjork, Höglund, Mattias, Borg, Åke, Jönsson, Göran, Ringnér, Markus“…However, we observed that the candidate genomic instability drivers BRCA1 and HORMAD1 displayed aberrant methylation linked to gene expression levels in some basal-like tumors. …”
Publicado 2016
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132096por Banerjee, Anwesha, Luong, Jonathan A., Ho, Anthony, Saib, Aeshah O., Ploski, Jonathan E.“…We validated one VPA-dysregulated candidate gene (Homer1a) using both quantitative PCR (qRT-PCR) and western blot. …”
Publicado 2016
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132097por Pandey, Ram Vinay, Walter, Pulverer, Kallmeyer, Rainer, Beikircher, Gabriel, Pabinger, Stephan, Kriegner, Albert, Weinhäusel, Andreas“…Currently, epigenome-wide discovery studies provide many candidate regions for which the MSREqPCR approach can be very effective to confirm the findings. …”
Publicado 2016
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132098por Koestler, Devin C., Jones, Meaghan J., Usset, Joseph, Christensen, Brock C., Butler, Rondi A., Kobor, Michael S., Wiencke, John K., Kelsey, Karl T.“…Here, we introduce a novel algorithm for Identifying Optimal Libraries (IDOL) that dynamically scans a candidate set of cell-specific methylation markers to find libraries that optimize the accuracy of cell fraction estimates obtained from cell mixture deconvolution. …”
Publicado 2016
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132099por Nama, Nassr, Menon, Kusum, Iliriani, Klevis, Pojsupap, Supichaya, Sampson, Margaret, O’Hearn, Katie, Zhou, Linghong (Linda), McIntyre, Lauralyn, Fergusson, Dean, McNally, James D.“…Results. A total of 2,579 candidate papers were identified, yielding 169 trials having one or more arms meeting eligibility criteria. …”
Publicado 2016
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132100por Lemos, Marcos V. A., Chiaia, Hermenegildo Lucas Justino, Berton, Mariana Piatto, Feitosa, Fabieli L. B., Aboujaoud, Carolyn, Camargo, Gregório M. F., Pereira, Angélica S. C., Albuquerque, Lucia G., Ferrinho, Adrielle M., Mueller, Lenise F., Mazalli, Monica R., Furlan, Joyce J. M., Carvalheiro, Roberto, Gordo, Daniel M., Tonussi, Rafael, Espigolan, Rafael, Silva, Rafael Medeiros de Oliveira, de Oliveira, Henrique Nunes, Duckett, Susan, Aguilar, Ignacio, Baldi, Fernando“…CONCLUSIONS: The identification of such regions and the respective candidate genes, such as ELOVL5, ESSRG, PCYT1A and genes of the ABC group (ABC5, ABC6 and ABC10), should contribute to form a genetic basis of the fatty acid profile of Nellore (Bos indicus) beef, contributing to better selection of the traits associated with improving human health. …”
Publicado 2016
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