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  1. 132281
    por Do, Kim
    Publicado 2018
    “…Results related to associations with DNA methylation in peripheral blood at age 18 years, specific forms of victimization and candidate genes in the stress response will be discussed. …”
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    16. DEVELOPMENTAL BIOMARKERS OF ENVIRONMENTAL ADVERSITY AND EPIGENETIC RISK FOR MAJOR PSYCHIATRIC DISORDERS: CLUES TO PATHOGENESIS
  2. 132282
    “…ABCG2, a member of the ATP-binding cassette (ABC) transporter family was the most significant candidate, which crucially showed reduced expression in HeLa-L. …”
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    Regulation of Human γδ T Cells by BTN3A1 Protein Stability and ATP-Binding Cassette Transporters
  3. 132283
    “…Both regimens of opioid with IV-PCA may serve as promising candidates for good postoperative pain management, and provide with similar postoperative recovery for the patients undergoing radical surgery for colorectal cancer. …”
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    Prospective investigation of intravenous patient-controlled analgesia with hydromorphone or sufentanil: impact on mood, opioid adverse effects, and recovery
  4. 132284
    “…We setup two experiments for a synonym detection task, each with four raters, and 3672 pairs of terms (target term and candidate term) from the word embeddings created. For Experiment I, the target terms for 64 UniProtKB entries were those that appear in the titles/abstracts; Experiment II involves 63 UniProtKB entries and the target terms are a combination of terms from PubMed titles/abstracts with terms (i.e. increased context) from the CVDO protein class expressions and labels. …”
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    Deep learning meets ontologies: experiments to anchor the cardiovascular disease ontology in the biomedical literature
  5. 132285
    “…Future studies should explore whether miR-186-5p may serve as a candidate prognostic indicator and a therapeutic target for the treatment of aggressive prostate cancer. …”
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    Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells
  6. 132286
    “…Ingenine F may provide new promising candidates for potential cytotoxic agent. SUMMARY: Ingenine F, a new 1,2,3,4-THβCs derivative (4) and three known alkaloids (1-3) were isolated from A. ingens. …”
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    Ingenine F: A New Cytotoxic Tetrahydro Carboline Alkaloid from the Indonesian Marine Sponge Acanthostrongylophora ingens
  7. 132287
    “…Using two newly derived congenic strains, we aimed to investigate the effect of one of the prime candidates for this pharmacogenetic interaction, the Zbtb16 gene. …”
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    Single-Gene Congenic Strain Reveals the Effect of Zbtb16 on Dexamethasone-Induced Insulin Resistance
  8. 132288
    “…BACKGROUND: Several candidate genes have been identified in relation to lipid metabolism, and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene polymorphisms are major sources of genetically determined variation in lipid concentrations. …”
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    Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors
  9. 132289
    “…CONCLUSIONS: Several candidate biomarkers for baseline prediction of ACI outcome were identified. …”
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    Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation
  10. 132290
    “…Some IFN-sensitive influenza vaccine candidates with modified non-structural protein 1 (NS1) are highly attenuated in IFN-competent hosts but induce robust antiviral immune responses. …”
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    A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus
  11. 132291
    “…CONCLUSIONS: In vitro assay employing the recombinant enzymes revealed that KstD2 was the most promising candidate for biocatalysis in biotransformation of AD. …”
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    Identification, function, and application of 3-ketosteroid Δ1-dehydrogenase isozymes in Mycobacterium neoaurum DSM 1381 for the production of steroidic synthons
  12. 132292
    “…We hypothesized that COPD patients would have increased aortic inflammation and stiffness, as candidate mechanisms mediating increased cardiovascular risk, compared to two negative control groups: healthy never-smokers and smokers without COPD. …”
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    Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease
  13. 132293
    “…IMPORTANCE The nonhuman primate (NHP) model is the most widely recognized tool for assessing the protective activity of dengue vaccine candidates, based on the prevention of postinfection DENV viremia. …”
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    Improvement of the Dengue Virus (DENV) Nonhuman Primate Model via a Reverse Translational Approach Based on Dengue Vaccine Clinical Efficacy Data against DENV-2 and -4
  14. 132294
    “…Bioinformatic analysis was used to select the candidate gene for potential target regulation of miR-155, Sirt1. …”
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    Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease
  15. 132295
    “…BACKGROUND: Many genome- and epigenome-wide association studies (GWAS and EWAS) and studies of promoter methylation of candidate genes for inflammatory bowel disease (IBD) have demonstrated significant associations between genetic and epigenetic changes and IBD. …”
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    Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease
  16. 132296
    “…Moreover, we identified 184 circRNAs candidates using the CircRNA Identifier (CIRI) software, of which 32 circRNAs were specifically expressed in untreated samples and 83 circRNAs in TYLCV samples. …”
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    Re-analysis of long non-coding RNAs and prediction of circRNAs reveal their novel roles in susceptible tomato following TYLCV infection
  17. 132297
    “…RESULTS: Expression levels of the eight candidate miRNAs in cervical tissue samples (n = 58) and hrHPV-positive cervical scrapes from a screening population (n = 187) and cancer patients (n = 38) were verified by quantitative RT-PCR. …”
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    Triage of high-risk HPV-positive women in population-based screening by miRNA expression analysis in cervical scrapes; a feasibility study
  18. 132298
    “…A time-lapse heatmap determined 81 differentially expressed genes (DEG) with at least three hits in our model at all-time points, suggesting key candidates with a high impact on muscle regeneration. …”
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    Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma—A Broad Spectrum Analysis
  19. 132299
    “…Thus, these genes may be potential prognostic biomarker candidates in GC.…”
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    Prognostic value of hypoxia-inducible factor-1 alpha and prolyl 4-hydroxylase beta polypeptide overexpression in gastric cancer
  20. 132300
    “…The major transcription factor families identified in this study includes MYB, AP2-EREBP, bHLH, C2H2 and NAC. CONCLUSION: Candidate genes identified in this study for nitrate uptake and transport can be targeted and utilized for further studies in watermelon breeding and improvement programs to improve N uptake and utilization efficiency. …”
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    Genome-wide expression profiling of leaves and roots of watermelon in response to low nitrogen
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