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  1. 132361
    por Chen, Lai-Te, Jiang, Chen-Yang
    Publicado 2018
    “…Therefore, miR-15a-5p, miR-17-5p, miR-19b-3p, and miR-20a-5p were promising candidate biomarkers for differentiating an ES from TS. …”
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    MicroRNA Expression Profiles Identify Biomarker for Differentiating the Embolic Stroke from Thrombotic Stroke
  2. 132362
    “…A role of galanin in depression is also supported by a recent candidate gene study, showing that variants in genes for galanin and its three receptors confer increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events. …”
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    Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness
  3. 132363
    “…The residual efficacy of the Fludora(®) Fusion combination evaluated at 10 months shows this product is a good candidate for IRS interventions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12936-018-2633-6) contains supplementary material, which is available to authorized users.…”
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    Small-scale field evaluation of the efficacy and residual effect of Fludora(®) Fusion (mixture of clothianidin and deltamethrin) against susceptible and resistant Anopheles gambiae populations from Benin, West Africa
  4. 132364
    “…CONCLUSION: Based on its overwhelming potency against the tested cell lines and in angiogenesis assay, compound 1 can be further evaluated mechanistically and can be developed as anticancer drug candidate. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40659-018-0209-0) contains supplementary material, which is available to authorized users.…”
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    Isolation of dihydrobenzofuran derivatives from ethnomedicinal species Polygonum barbatum as anticancer compounds
  5. 132365
    “…For some association studies such as candidate gene approaches, it may be unfeasible to genotype a numerous set of markers to avoid false positive results. …”
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    A panel of 32 AIMs suitable for population stratification correction and global ancestry estimation in Mexican mestizos
  6. 132366
    “…Women with newly diagnosed histologically confirmed International Federation of Gynecology and Obstetrics stage IB to IVA carcinoma of the cervix who were candidates for chemotherapy and radiation therapy (CRT) were allocated 2:1 to PET-CT plus CT of the abdomen and pelvis or CT alone. …”
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    Effect of Positron Emission Tomography Imaging in Women With Locally Advanced Cervical Cancer: A Randomized Clinical Trial
  7. 132367
    “…CONCLUSIONS: Collectively, these results suggested that XAG could be served as a promising candidate for the treatment and prevention of HCC. …”
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    Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma
  8. 132368
    “…Furthermore, these analyses suggest that Solyc01g007130.3 is a potential candidate to be regarded as Cf-10 gene. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12870-018-1616-7) contains supplementary material, which is available to authorized users.…”
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    Molecular mapping of the Cf-10 gene by combining SNP/InDel-index and linkage analysis in tomato (Solanum lycopersicum)
  9. 132369
    “…CONCLUSIONS: The data presented here suggest B. velezensis 9D-6 as a candidate plant growth promoting bacterium (PGPB) and biopesticide, which uses a unique complement of antimicrobials, as well as other mechanisms, to protect plants against phytopathogens. …”
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    Characterization and complete genome analysis of the surfactin-producing, plant-protecting bacterium Bacillus velezensis 9D-6
  10. 132370
    “…The search strategy for the updated review on e-cigarettes will be developed using that of the candidate systematic review. The MEDLINE®, PsycINFO, Embase, and the Cochrane Library electronic databases will be searched as of 2008 for the overview of reviews and from the last search date of the selected review for the updated review. …”
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    Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review
  11. 132371
    “…Additionally, we tested the sensitivity of those candidate proteins to phosphatidylinositol-specific phospholipase C (PI-PLC), an enzyme that cleaves GPI from GPI-APs. …”
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    Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophrenia
  12. 132372
    “…Understanding the functions of these regulated miRNAs will aid the investigation of T. gondii infectious diseases, and the differentially expressed miRNAs might be candidate drug targets for T. gondii infection in pigs. …”
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    Expression profile of microRNAs in porcine alveolar macrophages after Toxoplasma gondii infection
  13. 132373
    “…Applying our pipeline genome-wide using summary statistics from GWAS uncovered 233 association signals at loci which represent promising candidates for further evaluation. CONCLUSIONS: Disease susceptibility can be influenced by differential changes in tissue-specific gene expression and DNA methylation. …”
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    Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
  14. 132374
    “…FINDINGS: We describe DNA methylation findings in buccal swab DNA of the 3–7-year-old children (CBT(N) = 12, TAU(N) = 11), at a genome-wide level at 770,668 CpG sites and at 729 CpG sites spanning 16 a priori selected candidate genes, including the glucocorticoid receptor (NR3C1). …”
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    Exploring the effect of antenatal depression treatment on children’s epigenetic profiles: findings from a pilot randomized controlled trial
  15. 132375
    “…Thus, let-7d and miR-205 are good candidates for new HNSCC biomarkers.…”
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    Low let-7d and high miR-205 expression levels positively influence HNSCC patient outcome
  16. 132376
    “…To address this, we first aimed to identify novel abiotic stresses that enhance or suppress the elicitation of glyceollins and then used a comparative transcriptomics approach to search for TF gene candidates that may positively regulate glyceollin biosynthesis. …”
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    The NAC family transcription factor GmNAC42–1 regulates biosynthesis of the anticancer and neuroprotective glyceollins in soybean
  17. 132377
    “…TransDecoder identified 197,271 contigs that contained candidate-coding regions. Of a total of 50,230 unigenes, 34,470 (68.62% of the total unigenes) annotated to homologous proteins in the Protostome database (PANM-DB). …”
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    Transcriptome analysis of air-breathing land slug, Incilaria fruhstorferi reveals functional insights into growth, immunity, and reproduction
  18. 132378
    “…However, using coagulation and fibrinolytic markers, how one can best predict mortality to find out potential candidates for treatment of coagulopathy remains unclear. …”
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    Impact of initial coagulation and fibrinolytic markers on mortality in patients with severe blunt trauma: a multicentre retrospective observational study
  19. 132379
    “…Scanning the genome for overlapping runs of homozygosity (ROH) shared by more than 50% of horses, we identified homozygous regions (ROH islands) in order to investigate the gene content of those candidate regions by gene ontology and enrichment analyses. …”
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    High-resolution population structure and runs of homozygosity reveal the genetic architecture of complex traits in the Lipizzan horse
  20. 132380
    “…Methylation levels of candidate CpGs were assessed using pyrosequencing in the training dataset (tumor lesions and adjacent normal tissues from 46 CRCs) and the validation dataset (tumor lesions and paired normal tissues from 13 hyperplastic polyps, 129 adenomas, and 256 CRCs). …”
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    Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer
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