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  1. 132541
    “…This allowed us to identify putative candidate drugs which increased iodide uptake >2 SD above mean. …”
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    OR28-03 Drug Repurposing Identifies Inhibitors of the Proteostasis Network to Augment Radioiodine Uptake in Combinatorial Approaches Targeting Thyroid Cancer
  2. 132542
    “…A high index of suspicion is essential for timely treatment, which is limited to rest, optimal glycemic control, pain control and patients who are candidates low-dose aspirin. This condition resolves spontaneously over a few weeks to months in most patients and acknowledging this condition could provide timely relief and reassurance.…”
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    MON-670 An Overlooked Cause of Diabetic Pain
  3. 132543
    “…IGF 2 level was 780 ng/ml [333 - 967 ng/ml] while IGF-1 was < 10 ng/ml [32-200 ng/ml] He was not a candidate for surgery due to portal vein involvement and tumor radioembolization was unsuccessful. …”
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    SAT-117 Refractory Paraneoplastic Non Islet Cell Tumor Hypoglycemia (NICTH) from Hepatocellular Carcinoma Managed with Somatostatin Analogue and Glucocorticoids
  4. 132544
    “…This enhancement is thought to occur due to ligand transfer, however, FABP5 only binds a subset of reported PPARδ ligands. To find other candidate lipid transport proteins (LTPs), we performed a protein complementation assay (PCA) between LTPs and NRs. …”
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    SAT-LB124 Phosphatidylcholine Transfer Protein Interacts With PPARδ to Modulate Activity
  5. 132545
    “…Conclusion:In this pilot study, we propose PLK1 inhibitors as promising candidates for treatment of a subset of ACC patients that may be pre-selected according to the tumour molecular pattern. …”
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    SUN-LB22 PLK1 as a New Treatment Target for Adrenocortical Carcinoma
  6. 132546
    “…The study of miRNAs in PTC has shown that these molecules can help in the diagnosis, prognosis and also as therapeutic candidates [1]. miRNAs are known to be differentially expressed in PTC compared to non-cancerous tissue and a few studies have shown association with some clinico-pathological features. …”
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    SUN-119 Identification of Novel Mirnas Found to Be Differentially Expressed Between ATA Risk Stratification Groups in Papillary Thyroid Carcinoma
  7. 132547
    “…These results identified this locus as a candidate for explaining the dual dependence of Fshb expression on GnRH and activin/TGFβ signaling, and potential new evidence for upstream regulation of Fshb. …”
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    SAT-298 Integrative Single-Cell Transcriptomic and Epigenomic Landscape of Mouse Anterior Pituitary Cell Types
  8. 132548
    “…Oncology decided that the patient was a poor candidate for antineoplastic treatment therefore he was offered hospice care and eventually expired. …”
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    SAT-207 Adrenocortical Carcinoma in Untreated Congenital Adrenal Hyperplasia
  9. 132549
    “…The cortisol-responsive gene networks identified here represent candidate pathways to mediate cardiovascular risk attributable to elevated cortisol. (1) Bolton, et al. (2014) PLOS Genet. 10:e1004474., (2) Franzén et al. (2016). …”
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    OR09-04 Common Genetic Variants Associated with SERPINA6 Expression in Liver Influence Cortisol-Responsive Transcriptional Networks in Human Adipose Tissue
  10. 132550
    “…Gene co-expression is used in a guilt-by-association approach to prioritize candidate genes that could be involved in disease, and to gain insights into the functions of genes, protein relations, and signaling pathways. …”
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    MyoMiner: explore gene co-expression in normal and pathological muscle
  11. 132551
    por Du, Jian, Li, Xiaoying
    Publicado 2020
    “…There were 15,603 conclusive claims locally parsed using the search terms “conclusion*” and “conclude*” ready for semantic predications extraction by SemRep, and 325 candidate groups of semantic predications about combined medications were automatically discovered within 316 conclusive claims. …”
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    A Knowledge Graph of Combined Drug Therapies Using Semantic Predications From Biomedical Literature: Algorithm Development
  12. 132552
    “…Sequences of cox1, 16S and 12S mtDNA, as well as ITS, 18S and 28S rDNA from mites were retrieved from GenBank and used as candidate genes. Sequence alignment and analysis identified 28S rDNA as the suitable target gene. …”
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    Divergent domains of 28S ribosomal RNA gene: DNA barcodes for molecular classification and identification of mites
  13. 132553
    “…Methylation alteration is an optimal candidate to trace the signal from early stage tumors due to its early existence, multiple loci and stability in blood. …”
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    DNA methylation markers that correlate with occult lymph node metastases of non-small cell lung cancer and a preliminary prediction model
  14. 132554
    “…These regions contain well-known candidate genes related to morphology, adaptation, and domestication (e.g., KITLG, KIT, MITF, and MC1R), wool quality and quantity (e.g., DSG@, DSC@, and KRT@), growth and feed intake (e.g., HOXA@, HOXC@, LCORL, NCAPG, LAP3, and CCSER1), reproduction (e.g., CMTM6, HTRA1, GNAQ, UBQLN1, and IFT88), and milk-related traits (e.g., ABCG2, SPP1, ACSS1, and ACSS2). …”
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    High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia
  15. 132555
    “…CONCLUSIONS: Bet v 1 (a Pathogenesis-related 10 protein) and Art v 3 (a non-specific lipid transfer protein; nsLTP) are candidate molecular biomarkers for the diagnosis of food allergies in patients with season-specific pollen-related allergies. …”
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    Characteristics of pollen-related food allergy based on individual pollen allergy profiles in the Chinese population
  16. 132556
    por Velligan, Dawn, Sajatovic, Martha
    Publicado 2020
    “…DISCUSSION: The NOB checklist appears to be a useful tool to help identify patients who might be appropriate candidates for LAI and the full MAP program may help clinicians and consumers to work together to optimize the appropriate use of LAI in outpatient settings. …”
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    T236. A PROGRAM TO INCREASE THE APPROPRIATE USE OF LONG-ACTING ANTIPSYCHOTIC MEDICATIONS IN COMMUNITY SETTINGS
  17. 132557
    “…Exploring PD-L1 expression could help to select NSCLC candidates for immunotherapy. Fluorine-18 fluorodeoxyglucose (FDG) PET/CT could provide phenotypic information on malignant tumors. …”
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    PD-L1 expression correlation with metabolic parameters of FDG PET/CT and clinicopathological characteristics in non-small cell lung cancer
  18. 132558
    “…The monoamine oxidase A inhibitor drug harmine was suggested to have both antidepressant and anti-inflammatory properties and may, therefore, be a potential candidate for treatment of depression. AIM: The goal of this study was to assess the effects of harmine on behavior, brain BDNF levels, and microglia activation in control rats and a rat model of social stress. …”
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    Chronic harmine treatment has a delayed effect on mobility in control and socially defeated rats
  19. 132559
    “…To achieve this, free radical scavenging antioxidant, Trolox was conjugated on the surface of poly-lactic-co-glycolic acid (PLGA) nanoparticles for the protection of a candidate drug, melatonin that is used as a sleep aid medication in International Space Station (ISS). …”
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    PolyRad – Protection Against Free Radical Damage
  20. 132560
    “…Potential target genes modulated by miRNAs were identified by bioinformatics and candidate miRNAs were validated by molecular analysis. …”
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    High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model
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