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132581por Wang, Zhengxia, Ji, Ningfei, Chen, Zhongqi, Sun, Zhixiao, Wu, Chaojie, Yu, Wenqing, Hu, Fan, Huang, Mao, Zhang, Mingshun“…To investigate the potential targets of miR-1165-3p, biotin-microRNA pull-down products were sequenced, and the candidates were further verified with a dual-luciferase reporter assay. …”
Publicado 2020
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132582por Han, Jin-Hee, Cho, Jee-Sun, Ong, Jessica J. Y., Park, Ji-Hoon, Nyunt, Myat Htut, Sutanto, Edwin, Trimarsanto, Hidayat, Petros, Beyene, Aseffa, Abraham, Getachew, Sisay, Sriprawat, Kanlaya, Anstey, Nicholas M., Grigg, Matthew J., Barber, Bridget E., William, Timothy, Qi, Gao, Liu, Yaobao, Pearson, Richard D., Auburn, Sarah, Price, Ric N., Nosten, Francois, Rénia, Laurent, Russell, Bruce, Han, Eun-Taek“…These observations pose challenging questions to the selection of EBP and point out the importance of immune pressure and polymorphism required for inclusion of PvEBP as a vaccine candidate.…”
Publicado 2020
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132583por Hu, Zhiliang, Lv, Yanling, Xu, Chuanjun, Sun, Wenkui, Chen, Wei, Peng, Zhihang, Chen, Chen, Cui, Xiang, Jiao, Damin, Cheng, Cong, Chi, Yun, Wei, Hongxia, Hu, Chunmei, Zeng, Yi, Zhang, Xia, Yi, Yongxiang“…It is unclear whether corticosteroids could be a candidate for an early intervention strategy for patients with COVID-19. …”
Publicado 2020
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132584“…CONCLUSION: Baicalin protects human OA chondrocytes against IL-1β-induced apoptosis and the degradation of ECM through activating autophagy via miR-766-3p/AIFM1 axis and serves as a potential therapeutic candidate for OA treatment.…”
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132585por Iancu, Stefania D, Albu, Camelia, Chiriac, Liviu, Moldovan, Remus, Stefancu, Andrei, Moisoiu, Vlad, Coman, Vasile, Szabo, Laszlo, Leopold, Nicolae, Bálint, Zoltán“…CONCLUSION: The obtained stable, gold covered, iron oxide nanoparticles with reduced cytotoxicity, gave a negative T(2) signal in the MRI, which makes them suitable for candidates as contrast agent in small animal MRI applications.…”
Publicado 2020
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132586“…Fifty-three percent college students were satisfied with the online FFP giving an average rating of 3.2 to the software user interface and 85% affirmed that using the online software aided in providing anonymous responses helping them provide candid feedback. Seventy-five percent students agreed that online feedback system in 2019 had streamlined the feedback process and made it more efficient compared to the paper-based manual survey of 2018. …”
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132587por Yenerçağ, Mustafa, Arslan, Uğur, Doğduş, Mustafa, Günal, Özgür, Öztürk, Çağatay Erman, Aksan, Gökhan, Erdoğan, Güney, Gül, Sefa, Yontar, Osman Can, Şen, Ahmet“…The aim of the present study was to evaluate the ventricular repolarization by using the Tp-e interval, QT dispersion, Tp-e/QT ratio, and Tp-e/QTc ratio as candidate markers of ventricular arrhythmias in patients with newly diagnosed COVID-19. …”
Publicado 2020
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132588“…The main limitation is the costly wasting of time to hold a vast number of candidates sets with frequent itemsets, low minimum support, or large itemsets. …”
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132589“…Although Cys-rich derived CPPs of helicase (NSP13) can potentially fold into a cyclic conformation in endosomes with a higher rate of endosomal release, the most optimal SCV2-CPP candidates as vectors for drug delivery were SCV2-CPP118, SCV2-CPP119, SCV2-CPP122, and SCV2-CPP129 of NSP12 (RdRp). …”
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132590por Fan, Xiaoxu, Li, Lin, Zhao, Yonggang, Liu, Yutian, Liu, Chunju, Wang, Qinghua, Dong, Yaqin, Wang, Shujuan, Chi, Tianying, Song, Fangfang, Sun, Chengyou, Wang, Yingli, Ha, Dengchuriya, Zhao, Yang, Bao, Jingyue, Wu, Xiaodong, Wang, Zhiliang“…In this study, we aim to investigate if RPA/RAA can be a potential candidate for on-site, rapid and primary detection of ASFV. …”
Publicado 2020
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132591por Lauber, Chris, Correia, Nádia, Trumpp, Andreas, Rieger, Michael A., Dolnik, Anna, Bullinger, Lars, Roeder, Ingo, Seifert, Michael“…In addition, we learned gene regulatory networks to predict potential major regulators and found several genes and miRNAs with known roles in AML pathogenesis, but also interesting novel candidates involved in the regulation of hematopoiesis, cell cycle, cell differentiation, and immunity that may contribute to the observed survival differences of both subgroups and could therefore be important for prognosis. …”
Publicado 2020
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132592por Hsu, Justin Bo-Kai, Chang, Tzu-Hao, Lee, Gilbert Aaron, Lee, Tzong-Yi, Chen, Cheng-Yu“…Moreover, the expressions of ten (CTSZ, EFEMP2, ITGA5, KDELR2, MDK, MICALL2, MAP 2 K3, PLAUR, SERPINE1, and SOCS3) of these genes were significantly higher in GBM than in LGG, and comparing their expression levels to those of the proposed control genes (TBP, IPO8, and SDHA) could have the potential capability to classify patients into high- and low- risk groups, which differ significantly in the overall survival. Signatures of candidate genes were validated, by multiple microarray datasets from Gene Expression Omnibus, to increase the robustness of using these potential prognostic factors. …”
Publicado 2019
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132593“…OBJECTIVE: To illustrate the posterior longitudinal ligament is one of the tissue candidates who can contribute to low back pain (LBP). …”
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132594“…Our results would lay an important foundation for functional and evolutionary analysis of CqbZIPs, and provide promising candidate genes for further investigation in tissue specificity and their functional involvement in quinoa’s resistance to salt stress.…”
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132595“…In addition to its high medical and economic value, its adaptation to saline-alkali and coastal saline lands makes A. venetum an ideal candidate for use in vegetation restoration. To date, the study of A. venetum has been limited in the northwest region of China, little attention has been paid to the genetic diversity and population structure of A. venetum populations in the coastal region. …”
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132596por Bahrehbar, Khadijeh, Rezazadeh Valojerdi, Mojtaba, Esfandiari, Fereshteh, Fathi, Rouhollah, Hassani, Seyedeh-Nafiseh, Baharvand, Hossein“…Embryonic stem cell-derived mesenchymal stem cells (ES-MSCs) are attractive candidates for regenerative medicine because of their high proliferation and lack of barriers for harvesting tissue-specific MSCs. …”
Publicado 2020
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132597por Zhang, Yan-Ru, Yu, Zhen, Xiong, Wen-Jie, Liu, Xu-Xiang, Liu, Hui-Min, Cui, Rui, Wang, Qi, Chen, Wen-Ming, Qiu, Lu-Gui, Yi, Shu-Hua“…RESULTS: From IP/LCMS, we identified spleen tyrosine kinase (SYK) as a crucial candidate of TOSO-interacting protein and confirmed it by co-immunoprecipitation. …”
Publicado 2020
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132598“…MiR-133a-3p might be a potential candidate marker and therapeutic target for IA.…”
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132599por Miglietta, Federica, Dieci, Maria Vittoria, Tsvetkova, Vassilena, Griguolo, Gaia, Vernaci, Grazia, Menichetti, Alice, Faggioni, Giovanni, Giarratano, Tommaso, Mioranza, Eleonora, Genovesi, Elisa, Cumerlato, Enrico, Bottosso, Michele, Saibene, Tania, Michieletto, Silvia, Lo Mele, Marcello, Conte, Pierfranco, Guarneri, Valentina“…The better performance of RPCB versus RCB was in part due to the ability of RPCB to discriminate a subgroup of patients with a particularly worse prognosis after NACT, who may be candidates for clinical trials evaluating novel adjuvant strategies. …”
Publicado 2020
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132600por Aglas, Lorenz, Bethanis, Athanasios, Chrusciel, Paulina, Stolz, Frank, Gruen, Melanie, Jaakkola, Ulla-Marjut, Jongejan, Laurian, Yatkin, Emrah, Van Ree, Ronald“…Herein, we investigated the efficacy of the novel AIT candidate BM4, a hypoallergenic variant of Bet v 1, to induce treatment-relevant cross-reactive Bet v 1-specific IgG antibodies in two different mammals, Wistar rats and New Zealand White rabbits. …”
Publicado 2020
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