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132661“…The diagnostic and prognostic value of candidate genes was evaluated by ROC curve analysis and survival analysis, respectively. …”
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132662por Liu, Tengfei, Wang, Huiyu, Liu, Zhanyu, Pang, Ze, Zhang, Chuanzhong, Zhao, Ming, Ning, Bin, Song, Bo, Liu, Shanshan, He, Zili, Wei, Wanling, Wu, Junjiang, Liu, Yaguang, Xu, Pengfei, Zhang, Shuzhen“…We identified 392 proteins likely interacting with GmPIB1 and selected 20 candidate genes, and only 26S proteasome regulatory subunit GmPSMD (Genbank accession no. …”
Publicado 2021
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132663por Dan, Zheng, Xiujing, He, Ting, Luo, Xiaorong, Zhong, Hong, Zheng, Jiqiao, Yang, Yanchu, Li, Jing, Jing“…Tumor specific lncRNAs, which also showed biological function correlated with TNBC, were identified as potential candidates; and the target genes, which regulated by the identified lncRNAs, were predicted by the analysis of expression correlation and chromosome colocalization. …”
Publicado 2021
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132664por Want, Muzamil Y, Tsuji, Takemasa, Singh, Prashant K, Thorne, James L, Matsuzaki, Junko, Karasik, Ellen, Gillard, Bryan, Cortes Gomez, Eduardo, Koya, Richard C., Lugade, Amit, Odunsi, Kunle, Battaglia, Sebastiano“…To address this gap, we investigated the role of Wolf-Hirschhorn syndrome candidate 1 (WHSC1), a histone methyltransferase enzyme that targets dimethyl and trimethyl H3K36. …”
Publicado 2021
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132665“…Bi-variable logistic regression analysis was done and variables with p-value less than 0.05 were considered as candidate for multivariable logistic regression analysis. …”
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132666“…Based on our results, the ‘independents’ subgroup is a promising candidate for future collaborations in scientific research. …”
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132667“…Finding a biomarker to overcome these concerns are ongoing challenges and recently microRNAs (miRNAs) are attributed as possible candidates since they can regulate gene expressions in the human genome. …”
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132668“…Within 2 years, Captive individuals harbored Bacillus which contains numerous probiotic candidates and the complex carbon degraders of the family Saprospiraceae. …”
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132669por Longmei, Ningthaipuilu, Gill, Gurjit Kaur, Zaidi, Pervez Haider, Kumar, Ramesh, Nair, Sudha Krishnan, Hindu, Vermuri, Vinayan, Madhumal Thayil, Vikal, Yogesh“…Based on SNP association and haplotype mapping, nine and seven candidate genes were identified respectively, which belongs to different gene models having different biological functions in stress biology. …”
Publicado 2021
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132670por Feng, Cong, Wang, Lili, Chen, Xin, Zhai, Yongzhi, Zhu, Feng, Chen, Hua, Wang, Yingchan, Su, Xiangzheng, Huang, Sai, Tian, Lin, Zhu, Weixiu, Sun, Wenzheng, Zhang, Liping, Han, Qingru, Zhang, Juan, Pan, Fei, Chen, Li, Zhu, Zhihong, Xiao, Hongju, Liu, Yu, Liu, Gang, Chen, Wei, Li, Tanshi“…METHODS: Patients admitted from January 14 to February 26, 2020 with an epidemiological history of exposure to COVID-19 were included in the study [model development group (n=132) and validation group (n=32)]. Candidate features included clinical symptoms, routine laboratory tests, and other clinical information on admission. …”
Publicado 2021
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132671“…Scientists worldwide are competing to develop therapeutics and vaccines; currently, three drugs and two vaccine candidates have been given emergency authorization use. …”
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132672por Wang, Shuo, Wang, Li, Hu, Jianda, Qian, Wenbin, Zhang, Xi, Hu, Yu, Zhu, Qi, Chen, Bobin, Wu, Depei, Chang, Chung‐Chou H., Xu, Pengpeng, Zheng, Xiaoyun, Wei, Juying, Liu, Yao, Cui, Guohui, Tang, Yong, Ma, Yan, Huang, Haiwen, Yi, Hongmei, Zhao, Weili“…Due to poor clinical outcomes in the rituximab era, patients with refractory DLBCL may be potential candidates for novel treatment modalities.…”
Publicado 2021
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132673por Hardman, G., Hogg, R., Al-Aloul, M., Berman, M., Clark, S., Booth, K., Dark, J.H., Fisher, A.J., Al-Attar, N.“…Demand on capacity, concerns for transplant recipients, including the risks of nosocomial infection, and the availability and safety of donors, lead to continuation of transplantation for only urgent and super-urgent, in-patient candidates, in the UK from March to May 2020. The aim of this study is to evaluate the impact of these practice changes on heart and lung donor utilisation during the pandemic period. …”
Publicado 2021
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132674por Ruscito, Ilary, Gasparri, Maria Luisa, De Marco, Maria Paola, Costanzi, Flavia, Besharat, Aris Raad, Papadia, Andrea, Kuehn, Thorsten, Gentilini, Oreste Davide, Bellati, Filippo, Caserta, Donatella“…Identifying the clinical profile of breast cancer in women harboring BRCA1 gene hypermethylation may help oncologists select a subgroup of patients who may be candidates for BRCA1 methylation assessment, thus, possibly enlarging the cancer population who may benefit from new target-therapy agents. …”
Publicado 2021
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132675por Shao, Huilin, Zhang, Yue, Yan, Jie, Ban, Xinchao, Fan, Xiaojie, Chang, Xiaoyan, Lu, Zhaohui, Wu, Yan, Zong, Liju, Mo, Shengwei, Yu, Shuangni, Chen, Jie“…MicroRNAs (miRNAs) are promising candidates that can be identified in peripheral blood and can act as “liquid biopsy” biomarkers. miR-483-3p is overexpressed in the tumor tissue of pancreatic duct adenocarcinoma, but its potential as noninvasive biomarker remains unknown. …”
Publicado 2021
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132676por Brown, Samuel M., Peltan, Ithan, Kumar, Naresh, Leither, Lindsay, Webb, Brandon J., Starr, Nathan, Grissom, Colin K., Buckel, Whitney R., Srivastava, Rajendu, Butler, Allison M., Groat, Danielle, Haaland, Benjamin, Ying, Jian, Harris, Estelle, Johnson, Stacy, Paine, Robert, Greene, Tom“…Early in the pandemic, hydroxychloroquine and azithromycin were two such candidates. Objectives: To assess the relative efficacy of hydroxychloroquine and azithromycin among hospitalized patients with COVID-19. …”
Publicado 2021
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132677por França, Ana Caroline Barbosa, Françoso, Kátia Sanches, Marques, Rodolfo Ferreira, Trossini, Gustavo H. G., Gomes, Renan A., Póvoa, Marinete M., Cunha, Maristela G., Silveira, Eduardo L. V., Soares, Irene S.“…Only a small number of P. vivax vaccine formulations have successfully reached clinical trials relative to their P. falciparum counterparts. One of the candidate antigens for a blood-stage P. vivax vaccine is apical membrane antigen 1 (PvAMA-1). …”
Publicado 2021
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132678por Tang, JingTong, Gao, Wei, Liu, Gang, Sheng, WeiWei, Zhou, JianPing, Dong, Qi, Dong, Ming“…CONCLUSION: Our results suggest that miR-944 suppresses the aggressive biological processes by directly repressing GATA6 expression and could be a potential candidate for therapeutic applications in CRC.…”
Publicado 2021
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132679por Qureshi, Muhammad Asif, Khan, Saeed, Tauheed, Muhammad Sohaib, Ali Syed, Sofia, Ujjan, Ikram Din, Lail, Amanullah, Sharafat, Shaheen“…CONCLUSION: Our findings unravel several un-explored avenues related to the role of TC2N in tumourigenesis of several cancers, suggesting TC2N as an important player and a potential candidate for tumour-therapy.…”
Publicado 2020
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132680por Zeng, Yun-Zhu, Zhang, Yong-Qu, Chen, Jiong-Yu, Zhang, Li-Ying, Gao, Wen-Liang, Lin, Xue-Qiong, Huang, Shao-Min, Zhang, Fan, Wei, Xiao-Long“…TRPC1 could be a new candidate tumor suppressor gene and a new prognostic factor of ESCC.…”
Publicado 2021
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