“…RESULTS: Out of all the candidates, majority of the HCWs were men (61.9%) and were doctors (62.4%). …”
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“…DFT calculations suggested that studied compounds showed the lowest gap energy and were chemically reactive, and isolated compounds may serve as potential drug candidates that corroborate with the traditional uses of studied plants.…”
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“…Studies investigating PGE-M in prostate cancer are lacking even though chronic inflammation is a candidate risk factor for the disease. We investigated the association of PGE-M with lethal prostate cancer. …”
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“…Metabolic parameters on (18)F-FDG PET/CT have a potential role for (18)F-FDG PET/CT in selecting candidate LUAD for treatment with checkpoint inhibitors.…”
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“…While most germline polymerase variants showed no clear functional consequences, we identified a candidate p.T466A affecting the exonuclease domain of POLE, which might be underlying the early onset in a case with childhood CRC. …”
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“…In conclusion, the results of the present study suggested that ARR may exert anti-inflammatory effects by downregulating NF-κB and activating Nrf2-mediated inflammatory responses, suggesting that ARR may be an attractive anti-inflammatory candidate drug.…”
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“…To improve the application of BiFab format in investigational biodrugs, we have applied sortase A-mediated “bio-click” chemistry to generate BiFab, for facile assembly of Fab molecules that have been expressed and stored as BiFab module candidates. The BiFabs made by our method stimulate T cell proliferation and activation with favorable in vitro and in vivo anti-tumor activit. …”
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“…As a first step in understanding this process, an assessment of chemoreception genes belonging to the larval and adult stages of Hermetia illucens was conducted together with candidate VOCs that potentially regulate adult females searching for oviposition sites and phagostimulants for their larval progeny. …”
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“…RESULTS: Among the 3045 enrolled HIV patients, 106 had an HCV coinfection. Of the 11 candidate predictors (from history-taking, laboratory testing), seven had an adjusted likelihood ratio ≥ 1.5 or ≤ 0.67: ≥ 50 years (+1 point), diabetes mellitus (+1), partner/household member with liver disease (+1), generalized pruritus (+1), platelets < 200 × 10(9)/L (+1), aspartate transaminase (AST) < 30 IU/L (-1), AST-to-platelet ratio index (APRI) ≥ 0.45 (+1), and APRI < 0.45 (-1). …”
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“…METHODS: A retrospective analysis of 1,152 HPS candidates listed with an approved HPS model for end-stage liver disease (MELD) exception was performed. …”
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“…BACKGROUND: Concurrent chemoradiotherapy (CCRT) has become the standard of care in esophageal carcinoma patients who are not surgical candidates. The efficacy of induction chemotherapy (IC) or consolidation chemotherapy (CCT) for unresectable esophageal cancer (EC) treated with CCRT is unclear. …”
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“…Among these, polyvinyl alcohol (PVA) hydrogels have shown to be very promising candidates due to their biocompatibility, high degree of swelling, and elastic and rubbery nature, which allows them to mimic the natural tissues [1]. …”
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“…We believe that structural variant-based GWASs can also be used in other plants, animal species, and humans and be combined with deep sequencing GWASs to precisely identify candidate genes and genetic architecture components.…”
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“…ChIP‐seq data indicated that CGRP significantly altered H3K9ac enrichments on gene promoters in astroglial cells following CGRP treatment, including 151 gaining H3K9ac and 111 losing this mark, which mostly enriched in proliferation, autophagy, and macrophage chemotaxis processes. qRT‐PCR verified expressions of representative candidate genes (ATG12, ATG4C, CX3CR1, MMP28, MTMR14, HMOX1, RET) and RTCA verified astrocyte proliferation. …”
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“…Farnesol is a quorum-sensing molecule with a potential antifungal and/or adjuvant effect; it may be a promising candidate in alternative treatment regimens. To gain further insights into the farnesol-related effect on C. auris, genome-wide gene transcription analysis was performed using transcriptome sequencing (RNA-Seq). …”
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“…We compare the performance of a large pool of candidate models using a combination of posterior-predictive simulation and Bayes factors. …”
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“…The imaging probe, (68)Ga-DOTA-KEK-(GX1)(2), was successfully prepared, which provides a candidate probe for PET and Cerenkov diagnosis of gastric cancer.…”
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“…We have been offering the option of the combined technique to fertility preservation patients for a couple of years and have performed it in a series of eight candidate patients. All patients had enough time for COH before oncology treatments. …”
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“…Considering that DEF and DM performed similarly to PBO, they may be good candidates for inclusion in formulated pyrethroid products to increase their efficacy against resistant mosquitoes. …”
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“…Our findings suggest the mutant as a promising vaccine candidate against EV-A71 infection.…”
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