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132801por Rahimzadeh, Poupak, Faiz, Seyed Hamid Reza, Latifi-Naibin, Kaveh, Alimian, Mahzad“…In this single-blinded randomized clinical trial, the patients who were candidates for laparoscopic cholecystectomy were randomly divided into the two groups (n = 38 per group). …”
Publicado 2022
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132802por Sobouti, Farhad, Aryana, Mehdi, Dadgar, Sepideh, Alizadeh Navaei, Reza, Rakhshan, Vahid“…Studies including comparator (HF [hydrofluoric acid] + silane + bonding) were candidates for meta-analysis. ARI scores were dichotomized. …”
Publicado 2022
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132803por Leclercq, Gabrielle, Haegel, Hélène, Toso, Alberto, Zimmermann, Tina, Green, Luke, Steinhoff, Nathalie, Sam, Johannes, Pulko, Vesna, Schneider, Anneliese, Giusti, Anna Maria, Challier, John, Freimoser-Grundschober, Anne, Larivière, Laurent, Odermatt, Alex, Stern, Martin, Umana, Pablo, Bacac, Marina, Klein, Christian“…METHODS: By screening a library of 52 Food and Drug Administration approved kinase inhibitors for their impact on T cell proliferation and cytokine release after CD3 stimulation, we identified mTOR, JAK and Src kinases inhibitors as potential candidates to modulate TCB-mediated cytokine release at pharmacologically active doses. …”
Publicado 2022
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132804“…OBJECTIVE: To investigate the clinical significance of differentially expressed circRNAs and candidate circRNAs in the transformation of oral leukoplakia (OLK) to oral squamous cell carcinoma (OSCC). …”
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132805por Gong, Zhihong, Platek, Mary E., Till, Cathee, Goodman, Phyllis J., Tangen, Catherine M., Platz, Elizabeth A., Neuhouser, Marian L., Thompson, Ian M., Santella, Regina M., Ambrosone, Christine B.“…We evaluated associations of selected candidate polymorphisms in genes in these pathways, and interactions with pre-diagnostic serum antioxidants, and the risk of prostate cancer among 1,598 cases and 1,706 frequency-matched controls enrolled in the PCPT. …”
Publicado 2022
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132806por Liu, Libao, Xu, Shilei, Huang, Lei, He, Jinyuan, Liu, Gang, Ma, Shaohong, Weng, Yimin, Huang, Shaohong“…Finally, ITGAL [univariate hazard ratio (HR) =0.80, 95% confidence interval (CI): 0.69–0.93, P<0.01; multivariate HR =0.59, 95% CI: 0.40–0.86, P=0.01] and KLRB1 (univariate HR =0.78, 95% CI: 0.69–0.89, P<0.01; multivariate HR =0.72, 95% CI: 0.58–0.90, P<0.01) were correlated with the T-cell receptor signaling pathway and anaplastic lymphoma kinase (ALK) fusion (ITGAL: P=0.034; KLRB1: P=0.050), and were considered as candidate biomarkers. A significant relation between KLRB1 expression level and TMB (P=3.6e−05) was identified, while no relation was detected for ITGAL (P=0.11). …”
Publicado 2021
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132807“…Our findings contribute to further understanding the pathogenesis of GBM and finding possible candidate genes for prognostic and therapeutic usage with GBM.…”
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132808“…Microarray experiments were conducted to identify differentially expressed genes (DEGs) by applying appropriate biostatistics to normalize and analyze the dataset. The candidate gene (IL27RA) was validated by quantitative reverse transcriptase-PCR (qRT-PCR) and immunohistochemistry (IHC). …”
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132809“…Although donor selection is a critical early process that can maximize the production yield, determining the promising candidate is challenging owing to the lack of effective biomarkers and variations of cell sources. …”
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132810por Kalafatis, Chris, Modarres, Mohammad Hadi, Apostolou, Panos, Tabet, Naji, Khaligh-Razavi, Seyed-Mahdi“…Emerging research in remote memory clinics has highlighted computerized cognitive tests, such as the Integrated Cognitive Assessment (ICA), as prominent candidates for adoption in clinical practice both during the pandemic and for post-COVID-19 implementation as part of health care innovation. …”
Publicado 2022
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132811por Daghals, Iyas, Sargurupremraj, Muralidharan, Danning, Rebecca, Gormley, Padhraig, Malik, Rainer, Amouyel, Philippe, Metso, Tiina, Pezzini, Alessandro, Kurth, Tobias, Debette, Stéphanie, Chasman, Daniel“…A cross-trait meta-analysis was used to identify novel candidate loci. Finally, potential causality of migraine susceptibility on stroke and CeAD was assessed by Mendelian randomization. …”
Publicado 2022
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132812por Zhang, Beibei, Fan, Mengnan, Fan, Jie, Luo, Yuhang, Wang, Jie, Wang, Yajing, Liu, Baoyuan, Sun, Yani, Zhao, Qin, Hiscox, Julian A., Nan, Yuchen, Zhou, En-Min“…Herein, we identified the RAS-related protein 1b (Rap1b) as a potential HEV-ORF2 protein interacting candidate. Experimental infection of chickens and cells with an avian HEV isolate from China (CaHEV) led to upregulated expression and activation of Rap1b both in vivo and in vitro. …”
Publicado 2022
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132813por Blandino, Alice, Scherer, Dominique, Rounge, Trine B., Umu, Sinan U., Boekstegers, Felix, Barahona Ponce, Carol, Marcelain, Katherine, Gárate-Calderón, Valentina, Waldenberger, Melanie, Morales, Erik, Rojas, Armando, Munoz, César, Retamales, Javier, de Toro, Gonzalo, Barajas, Olga, Rivera, María Teresa, Cortés, Analía, Loader, Denisse, Saavedra, Javiera, Gutiérrez, Lorena, Ortega, Alejandro, Bertrán, Maria Enriqueta, Gabler, Fernando, Campos, Mónica, Alvarado, Juan, Moisán, Fabrizio, Spencer, Loreto, Nervi, Bruno, Carvajal-Hausdorf, Daniel E., Losada, Héctor, Almau, Mauricio, Fernández, Plinio, Gallegos, Ivan, Olloquequi, Jordi, Fuentes-Guajardo, Macarena, Gonzalez-Jose, Rolando, Bortolini, Maria Cátira, Gallo, Carla, Linares, Andres Ruiz, Rothhammer, Francisco, Lorenzo Bermejo, Justo“…ABSTRACT: Long noncoding RNAs (lncRNAs) play key roles in cell processes and are good candidates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. …”
Publicado 2022
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132814por Zhang, Lifan, Ma, Huimin, Wan, Shijun, Zhang, Yueqiu, Gao, Mengqiu, Liu, Xiaoqing“…CONCLUSION: Rv1733c SLP, combined with ESAT-6 and CFP-10, might be used as a candidate antigen for T cell-based tuberculosis diagnostic tests to differentiate ATB from LTBI.…”
Publicado 2022
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132815“…Many patients present with advanced-stage disease and only 10% of patients are candidates for surgical resection. Early research has shown there is an increased incidence of gallbladder cancer among patients with gallstone ileus. …”
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132816por Kuil, Teun, Hon, Shuen, Yayo, Johannes, Foster, Charles, Ravagnan, Giulia, Maranas, Costas D., Lynd, Lee R., Olson, Daniel G., van Maris, Antonius J. A.“…An alternative hypothesis that ATP-dependent Pfk activity circumvents a need for PP(i) altogether was falsified by enzyme assays, heterologous expression of candidate genes, and whole-genome sequencing. As a secondary outcome, enzymatic assays confirmed functional annotation of clo1313_1832 as ATP- and GTP-dependent fructokinase. …”
Publicado 2022
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132817por Zhang, Shuangzhe, Gao, Chunhui, Das, Tuhin, Luo, Shuhong, Tang, Hao, Yao, Xinyi, Cho, Chih Yun, Lv, Jingqiao, Maravillas, Kino, Jones, Valerie, Chen, Xiaofeng, Huang, Ruopan“…The lack of a high throughput screening (HTS) platform for candidate drug screening means that no targeted COVID-19 treatments have been developed to date. …”
Publicado 2022
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132818por Campos, Gabriel Soares, Cardoso, Fernando Flores, Gomes, Claudia Cristina Gulias, Domingues, Robert, de Almeida Regitano, Luciana Correia, de Sena Oliveira, Marcia Cristina, de Oliveira, Henrique Nunes, Carvalheiro, Roberto, Albuquerque, Lucia Galvão, Miller, Stephen, Misztal, Ignacy, Lourenco, Daniela“…The inclusion of genotypes from American Angus sires heavily used in Brazil just marginally increased the GEBV accuracies for selection candidates.…”
Publicado 2022
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132819“…Given that the ability to form biofilm is related to the antibiotic resistance of P. aeruginosa, our results indicate potential candidates for biomarkers assisting in selection of the most effective treatment for P. aeruginosa infections. …”
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132820por Rangseekaew, Pharada, Barros-Rodríguez, Adoración, Pathom-aree, Wasu, Manzanera, Maximino“…Our results demonstrate the potential of deep-sea D. abyssi MT1.1(T) to mitigate salt stress in tomato seedlings and as a candidate of eco-friendly bio-inoculants for sustainable agriculture.…”
Publicado 2022
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