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132841por Wang, Yuhan, Yao, Mingyan, Wang, Jincheng, Liu, Hongzhou, Zhang, Xuelian, Zhao, Ling, Hu, Xiaodong, Guan, Haixia, Lyu, Zhaohui“…RESULTS: From the 1,987 candidate articles identified in the initial search, 30 RCTs were eventually included in the analysis. …”
Publicado 2022
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132842“…Besides, SPAG5 and THEMIS2 might be candidate biomarkers for diagnosis of RA. LY-294002, trichostatin A, and troleandomycin may be potential drugs for RA.…”
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132843por Safaei-Farouji, Majid, Hasannezhad, Meysam, Rahimzadeh Kivi, Iman, Hemmati-Sarapardeh, Abdolhossein“…Finally, the two ET models with the linear regression model, which is of high interest to the industry, were applied to diagnose candidate layers along the formation for hydraulic fracturing. …”
Publicado 2022
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132844por Qi, Yi-Yu, Heng, Xia, Yao, Zeng-Ying, Qu, Shu-Yue, Ge, Ping-Yuan, Zhao, Xin, Ni, Sai-jia, Guo, Rui, Yang, Nian-Yun, Zhang, Qi-Chun, Zhu, Hua-Xu“…CONCLUSION: HLJDD is a good candidate for treating AD. This study provides a novel perspective on the potential roles of the sphingolipid metabolism in AD.…”
Publicado 2022
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132845“…Currently, a limited number of small molecular inhibitor and monoclonal antibody candidates that target TGF-β are in clinical development in combination with the following immune checkpoint inhibitors: SRK 181, an antibody inhibiting the activation of latent TGF-β1; NIS 793, a monoclonal antibody targeting TGF-β; and SHR 1701, a fusion protein consisting of an anti-PD-L1 monoclonal antibody fused with the extracellular domain of human TGF-β receptor II. …”
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132846por Caballero-Solares, Albert, Umasuthan, Navaneethaiyer, Xue, Xi, Katan, Tomer, Kumar, Surendra, Westcott, Jillian D., Chen, Zhiyu, Fast, Mark D., Skugor, Stanko, Taylor, Richard G., Rise, Matthew L.“…As a simulated co-infection model, the present study also serves as a source of candidate gene biomarkers for sea lice and bacterial co-infection.…”
Publicado 2022
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132847por Wang, Yaqi, Pei, Yuquan, Lv, Chao, Wang, Yuzhao, Wang, Jia, Zhao, Dachuan, Li, Xiang, Yang, Yue, Kim, Anthony W., Toker, Alper, Yan, Shi, Wu, Nan“…METHODS: Patients with resectable lung cancer scheduled to undergo lobectomy were identified as potential candidates. Once the re-expansion of the lung was confirmed via radiography the morning of postoperative day 1 and no air leak was detected, 180 patients were randomly assigned to intermittent chest tube clamping (the clamping group, n=90) or continuous gravity drainage (the control group, n=90). …”
Publicado 2022
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132848por Dias, O.M., Camargo, P., Carraro, R., Teixeira, R., Carvalho, G., Gomes Junior, O., Gaudio, T., Junior, J. Afonso, Samano, M.“…INTRODUCTION: Sensitized lung transplant (LTx) candidates have longer waiting times, decreased likelihood of transplant, and increased risk of death while on the waitlist. …”
Publicado 2022
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132849por Schwarz, S., Lang, C., Benazzo, A., Murakoezy, G., Jaksch, P., Klepetko, W., Hoetzenecker, K.“…CONCLUSION: Since severe cholangiopathy is associated with a high mortality after LTx, liver function should be thoroughly assessed in all post-COVID ARDS/fibrosis LTx candidates. In this preliminary observation, we found that GGT at the time of listing was the only parameter which appeared to predict this late complication. …”
Publicado 2022
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132850por Kantarci, Kejal, Nedelska, Zuzana, Chen, Qin, Senjem, Matthew L., Schwarz, Christopher G., Gunter, Jeffrey L., Przybelski, Scott A., Lesnick, Timothy G., Kremers, Walter K., Fields, Julie A., Graff-Radford, Jonathan, Savica, Rodolfo, Jones, David, Botha, Hugo, Knopman, David S., Lowe, Val, Graff-Radford, Neill R., Murray, Melissa M., Dickson, Dennis W., Reichard, R. Ross, Jack, Clifford R., Petersen, Ronald C., Ferman, Tanis J., Boeve, Bradley F.“…Given the prominent neurodegeneration in the cholinergic system, patients with prodromal dementia with Lewy bodies may be candidates for cholinesterase inhibitor treatment.…”
Publicado 2022
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132851por Uhomoibhi, John Omo-Osagie, Shode, Francis Oluwole, Idowu, Kehinde Ademola, Sabiu, Saheed“…While the study has lent credence to the significant role the compounds could play in developing potent SARS-CoV-2 candidate drugs against COVID-19, further structural refinement, and modifications of the compounds for subsequent in vitro as well as preclinical and clinical evaluations are underway.…”
Publicado 2022
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132852por Castro, Isabel, Carvajal, Patricia, Jara, Daniela, Aguilera, Sergio, Heathcote, Benjamín, Barrera, María-José, Aliaga-Tobar, Víctor, Maracaja-Coutinho, Vinicius, Urzúa, Ulises, Quest, Andrew F. G., González, Sergio, Molina, Claudio, Hermoso, Marcela, González, María-Julieta“…The aim of this study was to characterize the global profile of sRNAs in labial salivary glands (LSG) from SS-patients and to validate potential miRNA candidates implicated in glandular inflammation. LSG from 21 SS-patients and 9 sicca controls were analyzed. …”
Publicado 2022
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132853por Su, Wenwen, Wu, Leilei, Liang, Qichao, Lin, Xiaoyue, Xu, Xiaoyi, Yu, Shikai, Lin, Yitong, Zhou, Jiadong, Fu, Yang, Gao, Xiaoyan, Zhang, Bo, Li, Li, Li, Dan, Yin, Yongkui, Song, Gaochen“…Taken together, SBP-2A, isolated and purified from S. barbata showed good antitumour activity in vivo and in vitro, and SBP-2A may be a candidate drug for further evaluation in cancer prevention. …”
Publicado 2022
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132854por Zheng, Chun-Hui, Xu, Kai, Shan, Wen-Ping, Zhang, Ya-Kun, Su, Zhi-De, Gao, Xiang-Jin, Wang, Yu-Jue, Qi, Jian-Yu, Ding, Xiao-Yan, Wang, Chun-Ping, Wang, Yong-sheng“…BACKGROUND: Patients with concentric shrinkage mode after neoadjuvant chemotherapy (NAC) is considered to be ideal candidates for breast conserving treatment (BCT). While, what proportion of patients would represent CSM have not been well defined. …”
Publicado 2022
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132855por Wu, Shuyuan, Wu, Zhaofu, Xu, Huiling, Zhang, Jinli, Gu, Wenyi, Tan, Xiaohua, Pan, Zemin, Cao, Dongdong, Li, Dongmei, Yang, Lei, Li, Dongmei, Pan, Yuanming“…CONCLUSION: Upregulated miR-34a-5p in KSHV-infected SH-SY5Y cells suppressed cell proliferation and migration through down-regulating c-fos. miR-34a-5p was a candidate molecular drug for KSHV-infected neuronal cells.…”
Publicado 2022
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132856por Clark, Sharon L., Seppanen, Elke J., Kirkham, Lea-Ann S., Novotny, Laura A., Bakaletz, Lauren O., Cripps, Allan W., Corscadden, Karli, Coates, Harvey, Vijayasekaran, Shyan, Richmond, Peter C., Thornton, Ruth B.“…CONCLUSIONS: Australian Aboriginal otitis-prone children had lower serum IgG titres to 2/3 major NTHi vaccine candidate antigens, suggesting these children are unable to develop persistent IgG responses due to repeated NTHi exposure. …”
Publicado 2022
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132857“…Additionally, a set of target genes, PIK3R1, IGF1R, FZD6, IFNB2, ATF3, MB, CYP2B4, PSMD13, and TGFB1, were also identified as candidate genes associated with high-altitude hypoxia adaptation. …”
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132858por Zhao, Wenfeng, Zhang, Qing, Wang, Jiawen, Yu, Huan, Zhen, Xiaoyuan, Li, Lijuan, Qu, Yan, He, Yan, Zhang, Jianhua, Li, Chengtao, Zhang, Suhua, Luo, Bin, Huang, Jiang, Gao, Yuzhen“…Methods: Based on a candidate-gene-based approach and systematic screening strategy, this study analyzed an 8-bp insertion/deletion polymorphism (rs150703258) within downstream of NPC1 for the association with SCD risk in Chinese populations using 158 SCD cases and 524 controls. …”
Publicado 2022
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132859por Yin, Zhiqiu, Wang, Xin, Hu, Yujie, Zhang, Jikun, Li, Hui, Cui, Yanru, Zhao, Dongying, Dong, Xusheng, Zhang, Xiaohang, Liu, Kai, Du, Binghai, Ding, Yanqin, Wang, Chengqiang“…BY2G20 is a potential candidate for organic agriculture biofertilizers in saline-alkaline areas. …”
Publicado 2022
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132860por Abdelkhalek, Amr, El-Latif, Mona Abd, Ibrahim, Hesham, Hamad, Hesham, Showman, Marwa“…The remarkable characteristics of graphene make it a model candidate for boosting the effectiveness of nano-adsorbents with high potential owing to its large surface area, π–π interaction, and accessible functional groups that interact with an adsorbate. …”
Publicado 2022
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