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132921“…Variables with a p value less than 0.2 in bivariable regression were candidates for multivariable regression. Adjusted odds ratios with a 95% confidence intervals and p values less than 0.05 were used to determine the association between independent and dependent variables. …”
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132922por Oftung, Fredrik, Næss, Lisbeth M., Laake, Ida, Stoloff, Gregory, Pleguezuelos, Olga“…Previous reports demonstrated that FLU-v, a peptide-based broad-spectrum influenza vaccine candidate, induced antibody and cellular immune responses in humans. …”
Publicado 2022
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132923por Brahma, Priya, Jaitly, Priya, Das, Abhijit, Goyal, Rohit, Legrand, Melanie, d'Enfert, Christophe, Sanyal, Kaustuv“…RESULTS: Screening of overexpression library of the C. albicans ORFeome identified 14 unique Candidate genes from 1389 genes screened. While the functions of half of them have been verified in C. albicans, the remaining seven genes are not functionally characterized. …”
Publicado 2022
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132924por Niu, Zihan, Gao, Yuanjing, Xiao, Mengsu, Mao, Feng, Zhou, Yidong, Zhu, Qingli, Jiang, Yuxin“…CONCLUSIONS: CEUS demonstrated better diagnostic performance and greater clinical benefits than conventional US for the preoperative diagnosis of SLNs, showing its potential to select candidates for precluding axillary surgery in early breast cancer. …”
Publicado 2022
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132925por Wei, Xin, Yan, Xue-Jiao, Guo, Yu-Yan, Zhang, Jie, Wang, Guo-Rong, Fayyaz, Arsalan, Yu, Jiao“…We extracted GLCM-based features from grayscale images and applied ML to the classification of candidate predictive variables. The robustness and clinical utility of each model were evaluated based on the following factors: Receiver operating characteristic curve (ROC), decision curve analysis, and clinical impact curve. …”
Publicado 2022
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132926por You, Jianbin, Yang, Guoliu, Wu, Yi, Lu, Xuan, Huang, Shuyu, Chen, Qianshun, Huang, Chen, Chen, Falin, Xu, Xunyu, Chen, Liangyuan“…Then, plasma tRFs/tiRNAs were validated by quantitative real-time polymerase chain reaction (qRT-PCR), and their diagnostic efficiency was appraised by receiver operating characteristic curve analysis. The correlation of candidate plasma tRFs/tiRNAs with clinicopathological features was also analyzed. …”
Publicado 2022
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132927por Mykkänen, Anssi J. H., Taskinen, Suvi, Neuvonen, Mikko, Paile‐Hyvärinen, Maria, Tarkiainen, E. Katriina, Lilius, Tuomas, Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko“…In a stepwise linear regression candidate gene analysis among all 229 participants, SLCO1B1 c.521T>C (P = 1.9 × 10(−13)) and CYP3A4 c.664T>C (p.Ser222Pro, rs55785340, CYP3A4*2, P = 0.023) were associated with increased simvastatin acid AUC. …”
Publicado 2022
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132928por Wang, Xiaoxiao, Shen, Minxue, Zhang, Qian, Wang, Xiaomin, Zhang, Hanghao, Li, Tingxuan, Hu, Yuanping, Xia, Fan, Liao, Liqiu“…The main variables in the questionnaire including vaccination status, willingness to get the vaccines, candidate factors, and measures of adverse events in vaccinated individuals were used for analysis. …”
Publicado 2022
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132929por Li, Lingfei, Si, Xiaoli, Ruan, Jie, Ni, Zhumei, Li, Xiaoqin, Sang, Hongfei, Xia, Wenqing, Huang, Jinyu, Liu, Keqin, Lu, Shan, Jiang, Lin, Shao, Anwen, Yin, Congguo“…Circular RNAs (circRNA)s have been recently suggested as candidate biomarkers in diagnosing and prognosis of ischemic stroke. …”
Publicado 2022
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132930por Sermsuti-anuwat, Nithimar, Nampikul, Narongrit, Suwannimit, Rawitsara, Panthueng, Weerachon“…Hospital numbers (HN) were used to identify eligible candidates for this study. We calculated the sample size by assuming a finite population of 70,028 elderly patients with valid telephone numbers. …”
Publicado 2022
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132931por Maixner, Nitzan, Haim, Yulia, Blüher, Matthias, Chalifa-Caspi, Vered, Veksler-Lublinsky, Isana, Makarenkov, Nataly, Yoel, Uri, Bashan, Nava, Liberty, Idit F., Kukeev, Ivan, Dukhno, Oleg, Levy, Dan, Rudich, Assaf“…We performed Nanostring©-based miRNA profiling of VAT samples from all 24 patients. Candidate E2F1-related miRNAs were validated by qPCR in an independent cohort of patients with extreme obesity, with or without type-2-diabetes (T2DM) (n = 20). …”
Publicado 2022
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132932por Nurhayati, Awik Puji Dyah, Rihandoko, Andis, Fadlan, Arif, Ghaissani, Shabrina Syifa, Jadid, Nurul, Setiawan, Edwin“…The overall results demonstrated that trisindoline 1 and 3 are potential anti-cancer candidates capable of activating the apoptotic pathway.…”
Publicado 2022
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132933por Schindler, Lisa, Moosbauer, Jutta, Schmidt, Daniel, Spruss, Thilo, Grätz, Lukas, Lüdeke, Steffen, Hofheinz, Frank, Meister, Sebastian, Echtenacher, Bernd, Bernhardt, Günther, Pietzsch, Jens, Hellwig, Dirk, Keller, Max“…Insertion of Ga(3+) in the DOTA chelator gave potential PET ligands that were evaluated concerning NTS(1)R affinity (range of K(i) values: 1.2–21 nM) and plasma stability. Four candidates were labeled with (68)Ga(3+) and used for biodistribution studies in HT-29 tumor-bearing mice. [(68)Ga]UR-LS130 ([(68)Ga]56), containing an N-terminal methyl group and a β,β-dimethylated tyrosine instead of Tyr(11), showed the highest in vivo stability and afforded a tumor-to-muscle ratio of 16 at 45 min p.i. …”
Publicado 2022
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132934“…Overlap of the DEGs and WGCNA networks identified four shared genes, namely, ZNF695, CHEK1, C15ORF42 and EXO1, as candidate hub genes in MYCN positive NB. Three core genes, ZNF695, CHEK1 and C15ORF42, were finally identified by Lasso regression and Roc analyses. …”
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132935por Di Martino, Marcello, Vitale, Alessandro, Ferraro, Daniele, Maniscalco, Marilisa, Pisaniello, Donatella, Arenga, Giuseppe, Falaschi, Federica, Terrone, Alfonso, Iacomino, Alessandro, Galeota Lanza, Alfonso, Esposito, Ciro, Cillo, Umberto, Vennarecci, Giovanni“…ABSTRACT: Background: Locoregional therapies (LRTs) are commonly used to increase the number of potential candidates for liver transplantation (LT). The aim of this paper is to assess the outcomes of LRTs prior to LT in patients with hepatocellular carcinoma (HCC) beyond the listing criteria. …”
Publicado 2022
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132936por Kong, Delong, Hua, Xuan, Zhou, Rui, Cui, Jie, Wang, Tao, Kong, Fanyun, You, Hongjuan, Liu, Xiangye, Adu-Amankwaah, Joseph, Guo, Guo, Zheng, Kuiyang, Wu, Jianwei, Tang, Renxian“…This study suggested that D-Mt6 is a promising candidate drug as a derived peptide against A. baumannii.…”
Publicado 2022
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132937por Peng, Longfei, Cao, Zhangjun, Wang, Qi, Fang, Lu, Yan, Songbai, Xia, Dian, Wang, Jinyou, Bi, Liangkuan“…In order to identify the candidate genes that may exist in the occurrence and development of ccRCC, microarray datasets GSE6344, GSE16441, GSE36895, GSE53757 and GSE76351 had been downloaded from Gene Expression Omnibus (GEO) database. …”
Publicado 2022
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132938“…Compound Ph(2)SnL(1) inhibits the microbes effectively and it could be an effective and new candidate for the modulation of various infections. …”
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132939por Babey, Muriel, Krause, William, Zhang, Xiao, Argiris, Jennay, Nikkanen, Joni, Herber, Candice, Scheller, Erica, Ingraham, Holly“…Current studies are underway to ask if these candidate factors from the ARC impact bone mass or the osteogenic capacity of skeletal stem cells. …”
Publicado 2022
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132940“…As she was considered a poor surgical candidate for bilateral adrenalectomy, she was started on osilodrostat 10 mg twice daily and hydrocortisone 10 mg twice daily for a block and replace strategy. …”
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