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132941por Liu, Junting, Akcan, Tugce, Gabor, Rachel, Delgoffe, Brooke, Sharma, Shivy, Singh, Balwinder, Parsaik, Ajay K“…Logistic regression was used to estimate the effect of TSH level on depression in patients without or with thyroid diseases (untreated thyroid disease- not on any thyroid medications and treated thyroid disease - on thyroid medications). Candidate models included depression regressed on (1) TSH, (2) log-transformed TSH, (3) TSH level: normal (0.5-4.9), elevated (5. 0-9.9), very elevated (≥10), and model fit statistics were used to select the TSH-level model. …”
Publicado 2022
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132942por Gross, Joshua“…Based on these findings and the principle of ligand functional selectivity, we sought to identify new GHSR1a drug candidates that could distinguish between G protein and βarr pathways. …”
Publicado 2022
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132943por Seetharaman, Kavita“…Evaluation by the ophthalmologist confirmed the presence of thyroid eye disease with a clinical activity score of 6 out of 7 indicating severe thyroid eye disease and she was a candidate for treatment with teprotumumab. DISCUSSION: Apathetic hyperthyroidism was first described by Lahey in 1931, as a state of non-activated hyperthyroidism. …”
Publicado 2022
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132944por Antonini, Sonir, Bodoni, Aline Faccioli, Coeli-Lacchini, Fernanda, Gebenlian, Juliana L, Moreira, Ayrton C, Elias, Lucila L, Junior, Wilson Araujo Silva, Castro, Margaret, Leopoldino, Andreia Machado“…METHODS: Genomic DNA of a boy with FGD was evaluated by whole-exome sequencing (WES). Candidate variants were analyzed in silico and confirmed by Sanger sequencing. …”
Publicado 2022
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132945“…He was a poor surgical candidate because of the proximity of the mass to the neuro-vascular bundle and was treated with radiation during hospitalization. …”
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132946“…The discussion among different specialties, including general surgery, concluded that the patient was not a candidate for surgical intervention or tracheostomy, and recommendations were to proceed to palliative chemotherapy. …”
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132947“…. ≤0.153 mg/kg, aOR = 2.904, 95% CI, 1.371–6.150, P = 0.005), atropine usage (aOR = 0.463, 95% CI, 0.244–0.879, P = 0.019), and RAEs during extubation to transport (aOR = 5.004, 95% CI, 2.633–9.511, P < 0.001) as independent predictors of RAEs during transport. These six candidate predictors were used to develop a nomogram, which showed a C-statistic value of 0.809 and good calibration (P = 0.844). …”
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132948por Stejskal, Vlastimil, Tran, Hung Quang, Prokesová, Markéta, Zare, Mahyar, Gebauer, Tatyana, Policar, Tomas, Caimi, Christian, Gai, Francesco, Gasco, Laura“…Detailed knowledge about the inclusion levels for pikeperch (Sander lucioperca), a promising candidate for intensive aquaculture in Europe remains, however, fragmented. …”
Publicado 2022
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132949por Trignano, Emilio, Serra, Pietro Luciano, Pili, Nicola, Trignano, Claudia, Rubino, Corrado“…Our mathematical formula to calculate the AFG seems to be both predictive and a precise guide for surgical decision-making in planning the treatment of patients candidated for HBA. In fact, the analysis of Breast-Q(©) questionnaires shows a high grade of satisfaction among patients. …”
Publicado 2022
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132950por Giammalva, Giuseppe Roberto, Viola, Anna, Maugeri, Rosario, Giardina, Kevin, Di Bonaventura, Rina, Musso, Sofia, Brunasso, Lara, Cepeda, Santiago, Della Pepa, Giuseppe Maria, Scerrati, Alba, Mantovani, Giorgio, Ferini, Gianluca, Gerardi, Rosa Maria, Pino, Maria Angela, Umana, Giuseppe Emmanuele, Denaro, Luca, Albanese, Alessio, Iacopino, Domenico Gerardo“…The proposed protocol has been internally validated on eight patients and will be firstly applied to patients affected by WHO grade IV astrocytoma (glioblastoma—GBM) candidates for craniotomy and lesion removal. In a further stage, it will be generally applied to patients with primary or metastatic brain tumors. …”
Publicado 2022
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132951por Qiu, Anni, Xu, Huiwen, Mao, Liping, Xu, Buyun, Fu, Xiaoyu, Cheng, Jingwen, Zhao, Rongrong, Cheng, Zhounan, Liu, Xiaoxuan, Xu, Jingsheng, Zhou, Yan, Dong, Yang, Tian, Tian, Tian, Guangyu, Chu, Minjie“…Then, a two-phase case-control study was performed to evaluate the association between candidate apaQTL-SNPs and NSCLC risk. Results: A total of 7 LUAD- and 21 LUSC-associated apaQTL-SNPs were selected. …”
Publicado 2022
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132952por Piechna, Karolina, Żołyniak, Aleksandra, Jabłońska, Ewa, Noyszewska-Kania, Monika, Szydłowski, Maciej, Żerek, Bartłomiej, Kulecka, Maria, Rumieńczyk, Izabela, Mikula, Michał, Juszczyński, Przemysław“…This selectivity makes TRAIL an attractive therapeutic candidate. However, despite encouraging activity in preclinical models, clinical trials with TRAIL mimetics/death receptor agonists demonstrated insufficient activity, largely due to emerging resistance to these agents. …”
Publicado 2022
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132953“…VQCs are promising candidates for efficient utilizations of noisy intermediate scale quantum (NISQ) devices: classifiers involving M-dimensional datasets can be implemented with only [Formula: see text] qubits by using an amplitude encoding. …”
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132954“…Currently they serve as promising candidates for cancer treatment. Up to date there have been several in vitro and in vivo studies related to the topic of cytotoxicity and anticancer activity of extracts from latex-bearing plants towards various cell types. …”
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132955por Ahsan, Hajra, Shahid, Muhammad, Imran, Muhammad, Mahmood, Faisal, Siddique, Muhammad Hussnain, Ali, Hayssam M., Niazi, Muhammad B.K., Hussain, Sabir, Shahbaz, Muhammad, Ayyub, Mudassar, Shahzad, Tanvir“…Thus, the nanocomposite NiO/CuO-NC can be an excellent candidate for photodegradation as well as the adsorption of the dyes in aqueous media.…”
Publicado 2022
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132956“…HIGHLIGHTS: hADSCs have emerged as a valuable candidate for transplantation therapy of neurodegenerative diseases. …”
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132957por Malins, Sam, Figueredo, Grazziela, Jilani, Tahseen, Long, Yunfei, Andrews, Jacob, Rawsthorne, Mat, Manolescu, Cosmin, Clos, Jeremie, Higton, Fred, Waldram, David, Hunt, Daniel, Perez Vallejos, Elvira, Moghaddam, Nima“…Using participatory methodology, a multidisciplinary team proposed candidate language features that they thought would discriminate between high and low patient activation. …”
Publicado 2022
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132958por Busslinger, Sarah D., Tschan, Viviane J., Richard, Olivia K., Talip, Zeynep, Schibli, Roger, Müller, Cristina“…The enhanced therapeutic efficacy of [(225)Ac]Ac-SibuDAB as compared to that of [(225)Ac]Ac-PSMA-617 and reasonable safety data qualify this novel radioligand as a candidate for targeted α-therapy of prostate cancer.…”
Publicado 2022
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132959por Costa, Renzo, Fatourou, Evangelia, Hoppensteadt, Debra, Fareed, Jawed, Halaris, Angelos“…Anti-cardiolipin antibody (aCL IgM) is an inflammatory marker that has the potential to be such a candidate but there are insufficient studies to confirm this potential. …”
Publicado 2022
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132960por Stea, Emma Diletta, Skerka, Christine, Accetturo, Matteo, Pesce, Francesco, Wiech, Thorsten, Hartman, Andrea, Pontrelli, Paola, Conserva, Francesca, Castellano, Giuseppe, Zipfel, Peter F., Gesualdo, Loreto“…Given the role of FHRs in the complement system and the fact that this patient was a candidate for a kidney transplant, we studied the relevance of low FHR2 plasma levels through a set of functional in vitro assays. …”
Publicado 2022
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