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  1. 133081
    “…CONCLUSIONS: The avirulent RHΔompdcΔuprt strain can provide strong anti-T. gondii immune responses, and is a promising candidate for developing a safe and effective live attenuated vaccine. …”
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    A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats
  2. 133082
    “…CONCLUSIONS: Of several candidate genetic changes, the mutant Z. mobilis treated with cold plasma was conferred upon the facilitated aldehyde inhibitors tolerance and bioethanol production. …”
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    Cold plasma pretreatment reinforces the lignocellulose-derived aldehyde inhibitors tolerance and bioethanol fermentability for Zymomonas mobilis
  3. 133083
    por de Gonzalo-Calvo, David, Molinero, Marta, Benítez, Iván D., Perez-Pons, Manel, García-Mateo, Nadia, Ortega, Alicia, Postigo, Tamara, García-Hidalgo, María C., Belmonte, Thalia, Rodríguez-Muñoz, Carlos, González, Jessica, Torres, Gerard, Gort-Paniello, Clara, Moncusí-Moix, Anna, Estella, Ángel, Tamayo Lomas, Luis, Martínez de la Gándara, Amalia, Socias, Lorenzo, Peñasco, Yhivian, de la Torre, Maria Del Carmen, Bustamante-Munguira, Elena, Gallego Curto, Elena, Martínez Varela, Ignacio, Martin Delgado, María Cruz, Vidal-Cortés, Pablo, López Messa, Juan, Pérez-García, Felipe, Caballero, Jesús, Añón, José M., Loza-Vázquez, Ana, Carbonell, Nieves, Marin-Corral, Judith, Jorge García, Ruth Noemí, Barberà, Carmen, Ceccato, Adrián, Fernández-Barat, Laia, Ferrer, Ricard, Garcia-Gasulla, Dario, Lorente-Balanza, Jose Ángel, Menéndez, Rosario, Motos, Ana, Peñuelas, Oscar, Riera, Jordi, Bermejo-Martin, Jesús F., Torres, Antoni, Barbé, Ferran
    Publicado 2023
    “…Here, we first validated candidate microRNAs (miRNAs) as biomarkers for clinical decision-making in critically ill patients. …”
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    A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study
  4. 133084
    “…However, some patients with immune response-associated features and better prognosis may be candidate to treatment de-escalation and immunotherapy. …”
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    Clinical, pathological, and comprehensive molecular analysis of the uterine clear cell carcinoma: a retrospective national study from TMRG and GINECO network
  5. 133085
    “…METHODS: The dominant m6A regulators in EMs were analysed using RT‒PCR. Candidate targets and possible mechanisms of METTL3 were assessed by m6A-mRNA epitranscriptomic microarray and RNA sequencing. …”
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    METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing
  6. 133086
    “…Four miRNAs were identified, miR-10a-5p, miR-15a-5p, let-7a-5p, and let-7g-5p (p < 0.05), which could be used as possible candidates for measuring pathological forms of acute or chronic stress. …”
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    MiR-10a, miR-15a, let-7a, and let-7g expression as stress-relevant biomarkers to assess acute or chronic psychological stress and mental health in human capillary blood
  7. 133087
    “…CONCLUSIONS: ZDHHC21 p.T209S is a novel, candidate causal gene mutation in a Chinese FAD pedigree. …”
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    Aberrant palmitoylation caused by a ZDHHC21 mutation contributes to pathophysiology of Alzheimer’s disease
  8. 133088
    “…CONCLUSIONS: ZBH-01 can be an antitumor candidate drug for preclinical study in the future.…”
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    A novel camptothecin derivative, ZBH-01, exhibits superior antitumor efficacy than irinotecan by regulating the cell cycle
  9. 133089
    “…Exosomal circKIF20B is expected to be an easily accessible and alternative liquid biopsy candidate and potential therapeutic target in gefitinib-resistant NSCLC. …”
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    Exosome-derived circKIF20B suppresses gefitinib resistance and cell proliferation in non-small cell lung cancer
  10. 133090
    “…Baricitinib (BARI), an oral Janus Kinase 1/2 inhibitor, is approved in Europe, Japan, and other countries, for treatment of adults with moderate-to-severe AD who are candidates for systemic therapy. This post hoc analysis of a Phase 3 topical corticosteroid (TCS) combination therapy trial (BREEZE-AD7) aims to characterize patients who might benefit most from BARI. …”
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    Baseline Body Surface Area and Itch Severity Define Response to Baricitinib in Patients with Moderate-to-Severe Atopic Dermatitis at Week 16
  11. 133091
    “…The GO and KEGG analyses demonstrated that protein transport, positive regulation of apoptotic process, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, TNF signaling pathway, B cell receptor signaling pathway and Apoptosis may be potential candidate therapeutic targets for AIT of AR. From the PPI network, 20 hub genes were obtained. …”
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    Identification of key genes and the pathophysiology associated with allergen-specific immunotherapy for allergic rhinitis
  12. 133092
    “…It was found that the Shannon index of soil bacteria in CaKCoS was significantly higher than that in CaKCaM and CoSCaM, and the abundance of the dominant phyla, including Actinobacteria, Proteobacteria, Acidobacteria, Chloroflexi, Planctomycetes, Thaumarchaeota, Armatimonadetes, candidate_division_WPS-1, and Nitrospirae, increased significantly in CaKCoS and CaKCaM compared to that in CoSCaM. …”
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    High-Throughput Absolute Quantification Sequencing Reveals that a Combination of Leguminous Shrubs Is Effective in Driving Soil Bacterial Diversity During the Process of Desertification Reversal
  13. 133093
    “…The modifying effect of the candidate variables was assessed by fitting interaction models to the data of the RCT. …”
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    Potential effect modifiers for treatment with chiropractic manipulation versus sham manipulation for recurrent headaches in children aged 7–14 years: development of and results from a secondary analysis of a randomised clinical trial
  14. 133094
    “…Clostridium thermocellum ATCC 27405 is a candidate for ethanol production from lignocellulosic biomass using consolidated bioprocessing. …”
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    Kinetic characterization of annotated glycolytic enzymes present in cellulose-fermenting Clostridium thermocellum suggests different metabolic roles
  15. 133095
    “…ICE FALCON method was utilized to perform the causal inference. Candidate CpGs were quantified and validated using Sequenom MassARRAY platform in a community population. …”
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    Identification of key DNA methylation changes on fasting plasma glucose: a genome-wide DNA methylation analysis in Chinese monozygotic twins
  16. 133096
    “…They also provide a rich foundation for post-genomic research, including the selection of candidate gene-targets for innovative whitefly and virus-control strategies. …”
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    Comparative evolutionary analyses of eight whitefly Bemisia tabaci sensu lato genomes: cryptic species, agricultural pests and plant-virus vectors
  17. 133097
    “…Furthermore, targeting the activation of SIRT3 by honokiol provides a promising therapeutic candidate for diabetes-associated cognitive dysfunction. …”
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    SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes
  18. 133098
    “…These findings will provide further understanding of the regulatory roles of lncRNAs in BPH defense, and lay a foundation for functional research on the candidate lncRNAs. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12870-023-04374-w.…”
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    Comprehensive transcriptomic analysis of three varieties with different brown planthopper-resistance identifies leaf sheath lncRNAs in rice
  19. 133099
    “…Using a general estimating equation, a prediction curve for biomarker development was generated in the form of a best-fit regression line and 95% prediction interval, correlating individual predicted lesion radiation dose metrics, with candidate biomarkers (“predictors”) such as SUV(max) and activity in microcurie per gram, from a single imaging timepoint. …”
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    The use of single-timepoint images to link administered radioiodine activity (MBq) to a prescribed lesion radiation-absorbed dose (cGy): a regression-based prediction interval tool for the management of well-differentiated thyroid cancer patients
  20. 133100
    “…The data were then analyzed to identify candidates for constructing a circRNA-miRNA-mRNA network based on circRNA-miRNA interactions and miRNA-mRNA interactions. …”
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    Identifying circRNA-associated-ceRNA networks in juvenile spondyloarthropathies patients
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