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  1. 134341
    “…In bivariate analysis variables with a p-value ≤ 0.25 were selected as a candidate variable for the multivariable analysis. …”
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    Self-referrals and associated factors among laboring mothers at Dilla University Referral Hospital, Dilla, Gedeo Zone, Ethiopia: a cross-sectional study
  2. 134342
    “…To further increase our understanding of these, and other, genetic variant associations with injury, competition-wide AFL studies that use more players and a larger array of gene candidates is essential.…”
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    Genetic Variants within NOGGIN, COL1A1, COL5A1, and IGF2 are Associated with Musculoskeletal Injuries in Elite Male Australian Football League Players: A Preliminary Study
  3. 134343
    “…Demographic, clinical, and radiographic characteristics were considered candidate predictive factors. Radiographic variables included the Ahlbäck grade, hip–knee–ankle (HKA) angle, joint line convergence angle (JLCA), and TF subluxation. …”
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    Decision-making factors and their thresholds for total knee arthroplasty in lateral tibiofemoral osteoarthritis patients: a retrospective cohort study
  4. 134344
    “…In addition, molecular docking, Prime MM/GBSA (molecular mechanics/generalized Born surface area) analysis, molecular dynamics (MD) simulation, and drug-likeness screening were performed to identify potential phytodrugs candidates for COVID-19 treatment. In support of these approaches, we used a series of computational modeling approaches to develop therapeutic agents against COVID-19. …”
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    Discovery of putative inhibitors against main drivers of SARS-CoV-2 infection: Insight from quantum mechanical evaluation and molecular modeling
  5. 134345
    “…RESULTS: We searched for 4378 candidate articles, of which 12 studies were included in our study according to the inclusion and exclusion criteria. …”
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    Efficacy and safety of carbon ion radiotherapy for bone sarcomas: a systematic review and meta-analysis
  6. 134346
    “…Thus, AgB may be a drug candidate for IBD treatment. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13071-022-05498-y.…”
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    Echinococcus granulosus sensu stricto and antigen B may decrease inflammatory bowel disease through regulation of M1/2 polarization
  7. 134347
    “…Eligible participants were existing or candidate peer support group leaders affiliated with a scleroderma patient organization. …”
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    Effects of a support group leader education program jointly developed by health professionals and patients on peer leader self-efficacy among leaders of scleroderma support groups: a two-arm parallel partially nested randomised controlled trial
  8. 134348
    “…CONCLUSION: AU4, RG6 and RG5 can be potential bio-inoculants candidates as low cost agricultural inputs in acidic and/or alkaline soils for sustainable crop production. …”
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    Evaluation of inorganic phosphate solubilizing efficiency and multiple plant growth promoting properties of endophytic bacteria isolated from root nodules Erythrina brucei
  9. 134349
    “…There were no mutations in the pfk13 gene reported with validated and candidate or associated k13 mutation. An increased copy number of pfpm2, associated with piperaquine resistance, was found only in cases of reinfection. …”
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    Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia
  10. 134350
    por Kebede, Fassikaw, Kebede, Tsehay
    Publicado 2022
    “…Covariates having < 0.2 of P values in the bi-variable analysis were candidates transferred to the multivariable Cox proportional hazard regression model. …”
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    Incidence and predictors of attrition rate after children started inpatient treatments for complicated severe acute malnutrition in North West Ethiopia
  11. 134351
    “…This suggests that AgNPs gel may represent a promising future candidate for clinical use in regenerative endodontics. …”
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    Investigating the residual effect of silver nanoparticles gel as an intra-canal medicament on dental pulp stromal cells
  12. 134352
    “…CONCLUSIONS: In 90 LBP patients, the analyzed biomarkers, especially vitamin D, represent a small set of potential candidates for further research aimed at individualizing patient care. …”
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    The association of biomarkers with pain and function in acute and subacute low back pain: a secondary analysis of an RCT
  13. 134353
    “…The methylation status of 5 candidate marker CpG sites was assessed using a HPLC-based system, and for 3 of them sufficient sensitivity and specificity were successfully validated in the validation cohort. …”
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    Quantification of DNA methylation for carcinogenic risk estimation in patients with non-alcoholic steatohepatitis
  14. 134354
    “…We found potential candidates for novel associations including CSMD1 and a monostearyl alcohol triglyceride (m/z 781.7483, retention time (RT) 89.3 s); CALN1 and Tridecanol (m/z 283.2741, RT 27.6). …”
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    Comprehensive characterization of putative genetic influences on plasma metabolome in a pediatric cohort
  15. 134355
    “…The natural sweetener 5-keto-d-fructose is one such candidate. 5-Keto-d-fructose has a similar sweet taste quality as fructose. …”
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    Highly efficient fermentation of 5-keto-d-fructose with Gluconobacter oxydans at different scales
  16. 134356
    “…Besides, rabbit anti-rMSNOX serum presented complement-dependent mycoplasmacidal activity toward both MS and MG, indicating the MSNOX may be further studied as a potential protective vaccine candidate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12917-022-03556-2.…”
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    NADH oxidase of Mycoplasma synoviae is a potential diagnostic antigen, plasminogen/fibronectin binding protein and a putative adhesin
  17. 134357
    “…This critical attribute identifies the potential of ALZ-201 as a novel drug candidate for achieving a true, clinical therapeutic effect in AD. …”
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    Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer’s disease brain extracts
  18. 134358
    “…In this study, we analyzed the clinical characteristics and screened for mutant genes in two pedigrees with hereditary AT deficiency, and the functional effects of the pathogenic mutations were evaluated. METHODS: Candidate gene variants were analyzed by next-generation sequencing to screen pathogenic mutations in probands, followed by segregation analysis in families by Sanger sequencing. …”
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    Identification and characterization of two SERPINC1 mutations causing congenital antithrombin deficiency
  19. 134359
    “…BACKGROUND: We evaluated immunogenicity of SCB-2019, a subunit vaccine candidate containing a pre-fusion trimeric form of the SARS-CoV-2 spike (S)-protein adjuvanted with CpG-1018/alum. …”
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    Immunogenicity of an adjuvanted SARS-CoV-2 trimeric S-protein subunit vaccine (SCB-2019) in SARS-CoV-2-naïve and exposed individuals in a phase 2/3, double-blind, randomized study
  20. 134360
    “…Clonal selection through binding and functional studies in vitro, in silico and in vivo identified anti-PD-L1 clone 11B12-1 as the primary mAb candidate for immunotherapy modelling. The oncolytic virus (OV) and ICI combination approach was then evaluated using 11B12-1 and TILT-123 in a Syrian hamster model of pancreatic ductal adenocarcinoma (PDAC). …”
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    Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting
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