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134421por Castronovo, Chiara, Rossetti, Raffaella, Rusconi, Daniela, Recalcati, Maria P., Cacciatore, Chiara, Beccaria, Elena, Calcaterra, Valeria, Invernizzi, Pietro, Larizza, Daniela, Finelli, Palma, Persani, Luca“…These CNVs may pinpoint novel candidates relevant to female fertility and generate further insights into the mechanisms contributing to ovarian function. …”
Publicado 2014
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134422por Zhang, Rong, He, Yi-feng, Chen, Mo, Chen, Chun-mei, Zhu, Qiu-jing, Lu, Huan, Wei, Zhen-hong, Li, Fang, Zhang, Xiao-xin, Xu, Cong-jian, Yu, Long“…It can effectively narrow the range of candidates for colposcopic examination and cervical biopsy, thereby lowering the expense of cervical cancer prevention. …”
Publicado 2014
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134423por Chang, Yao-Yin, Kuo, Wen-Hung, Hung, Jui-Hui, Lee, Chien-Yueh, Lee, Yung-Hua, Chang, Ya-Chu, Lin, Wen-Chun, Shen, Cheng-Ying, Huang, Chiun-Sheng, Hsieh, Fon-Jou, Lai, Liang-Chuan, Tsai, Mong-Hsun, Chang, King-Jen, Chuang, Eric Y“…Quantitative reverse transcription PCR validations were carried out to examine miRNA expression levels. Potential target candidates of a miRNA were predicted using published target prediction algorithms. …”
Publicado 2015
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134424por Wang, Nannan, Bu, Ru, Duan, Zhiyu, Zhang, Xueguang, Chen, Pu, Li, Zuoxiang, Wu, Jie, Cai, Guangyan, Chen, Xiangmei“…In this study, we looked for differentially expressed miRNAs in IgAN and further evaluated the correlations between candidate miRNAs and the severity of IgAN. Methods. …”
Publicado 2015
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134425por Okda, Faten, Liu, Xiaodong, Singrey, Aaron, Clement, Travis, Nelson, Julie, Christopher-Hennings, Jane, Nelson, Eric A., Lawson, Steven“…Measurement of neutralizing antibody responses using the FFN assay may provide a valuable tool for assessment of vaccine candidates or protective immunity.…”
Publicado 2015
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134426por Höglund, Johanna K., Buitenhuis, Bart, Guldbrandtsen, Bernt, Lund, Mogens S., Sahana, Goutam“…CONCLUSION: This study 1) shows that many markers within FTI QTL regions were significantly associated with both AISH and IFLH, and 2) identified candidate genes for FTI located on BTA6 (GPR125), BTA13 (ANKRD60), BTA15 (GRAMD1B), and BTA24 (ZNF521). …”
Publicado 2015
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134427“…Some patients develop end-stage renal disease (ESRD) and may become candidates for kidney transplantation. Since kidney transplantation does not correct the underlying metabolic defect, transplant recipients have a high risk of recurrence of crystalline nephropathy, which can lead to graft loss. …”
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134428por YUAN, BAO, YU, WANG-YANG, DAI, LI-SHENG, GAO, YAN, DING, YU, YU, XIAN-FENG, CHEN, JIAN, ZHANG, JIA-BAO“…The relative expression of the candidate target genes, EphA2 and miR-26b, exhibited the opposite expression pattern. …”
Publicado 2015
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134429por Shukla, Priyank, Vogl, Claus, Wallner, Barbara, Rigler, Doris, Müller, Mathias, Macho-Maschler, Sabine“…Furthermore, among differentially expressed miRNAs, miRNAs that are known to be important regulators of EMT were detected and new candidates were predicted. New dog miRNAs were discovered after aligning our reads to that of other species in miRBase. …”
Publicado 2015
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134430por Honne, Kyoko, Hallgrímsdóttir, Ingileif, Wu, Chunsen, Sebro, Ronnie, Jewell, Nicholas P., Sakurai, Takeo, Iwamoto, Masahiro, Minota, Seiji, Jawaheer, Damini“…RESULTS: In the GEE models, borderline significant association was observed at 3 chromosomal regions (6q15: rs284515, p = 6.6x10(−7); 6q27: rs75908454, p = 6.3x10(−7) and 10q25.3: rs1679568, p = 8.1x10(−7)), extending to numerous SNPs in linkage disequilibrium (LD) across each region. Potential candidate genes in these regions include MAP3K7, BACH2 (6q15), GFRA1 (10q25.3), and WDR27 (6q27). …”
Publicado 2016
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134431por Zhou, Zhiqiang, Zhang, Chaoshu, Zhou, Yu, Hao, Zhuanfang, Wang, Zhenhua, Zeng, Xing, Di, Hong, Li, Mingshun, Zhang, Degui, Yong, Hongjun, Zhang, Shihuang, Weng, Jianfeng, Li, Xinhai“…Two MYB transcription factor genes, GRMZM2G325907 and GRMZM2G108892, which might regulate plant cell wall metabolism are the candidate genes for qPH10. CONCLUSIONS: Here, an ultra-high density accurate linkage map for a set of maize RILs was constructed using a GBS strategy. …”
Publicado 2016
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134432por Jamshed, Muhammad, Jia, Fei, Gong, Juwu, Palanga, Koffi Kibalou, Shi, Yuzhen, Li, Junwen, Shang, Haihong, Liu, Aiying, Chen, Tingting, Zhang, Zhen, Cai, Juan, Ge, Qun, Liu, Zhi, Lu, Quanwei, Deng, Xiaoying, Tan, Yunna, or Rashid, Harun, Sarfraz, Zareen, Hassan, Murtaza, Gong, Wankui, Yuan, Youlu“…Therefore, QTLs identified in the present study are an ideal candidate for MAS in cotton breeding programs to improve fiber quality. …”
Publicado 2016
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134433por Wang, Xiaofeng, Chen, Li, Jin, Heiying, Wang, Shuiming, Zhang, Yajie, Tang, Xiaoqing, Tang, Guiliang“…The sequencing data were then analyzed by bioinformatics for candidate diagnostic miRNAs, which were further validated for their up- or downregulation status. …”
Publicado 2016
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134434“…RESULTS: Genome-wide screening revealed 36 candidate GA metabolism genes were systematically identified for the first time; these genes included 3 MaCPS, 2 MaKS, 1 MaKO, 2 MaKAO, 10 MaGA20ox, 4 MaGA3ox, and 14 MaGA2ox genes. …”
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134435por Pronicka, Ewa, Piekutowska-Abramczuk, Dorota, Ciara, Elżbieta, Trubicka, Joanna, Rokicki, Dariusz, Karkucińska-Więckowska, Agnieszka, Pajdowska, Magdalena, Jurkiewicz, Elżbieta, Halat, Paulina, Kosińska, Joanna, Pollak, Agnieszka, Rydzanicz, Małgorzata, Stawinski, Piotr, Pronicki, Maciej, Krajewska-Walasek, Małgorzata, Płoski, Rafał“…Mutations in CLPB, SERAC1, TAZ genes were identified in neonates with 3-methylglutaconic aciduria (3-MGA) as a discriminative feature. New MD-related candidate gene (NDUFB8) is under verification. CONCLUSIONS: We suggest WES rather than targeted NGS as the method of choice in diagnostics of MD in children, including neonates with 3-MGA aciduria, who died without determination of disease cause and with limited availability of laboratory data. …”
Publicado 2016
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134436por Darton, Thomas C., Jones, Claire, Blohmke, Christoph J., Waddington, Claire S., Zhou, Liqing, Peters, Anna, Haworth, Kathryn, Sie, Rebecca, Green, Christopher A., Jeppesen, Catherine A., Moore, Maria, Thompson, Ben A. V., John, Tessa, Kingsley, Robert A., Yu, Ly-Mee, Voysey, Merryn, Hindle, Zoe, Lockhart, Stephen, Sztein, Marcelo B., Dougan, Gordon, Angus, Brian, Levine, Myron M., Pollard, Andrew J.“…In this study, we aimed to evaluate the protective efficacy of a single dose of the oral vaccine candidate, M01ZH09, in susceptible volunteers by direct typhoid challenge. …”
Publicado 2016
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134437por Fabiani, Iacopo, Scatena, Cristian, Mazzanti, Chiara Maria, Conte, Lorenzo, Pugliese, Nicola Riccardo, Franceschi, Sara, Lessi, Francesca, Menicagli, Michele, De Martino, Andrea, Pratali, Stefano, Bortolotti, Uberto, Naccarato, Antonio Giuseppe, La Carrubba, Salvatore, Di Bello, Vitantonio“….; 63 % Female) with severe AVS and preserved LV ejection fraction (EF), candidate to surgical aortic valve replacement (sAVR) were enrolled. …”
Publicado 2016
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134438por Rashidi, Mohsen, Ziai, Seyed Ali, Moini Zanjani, Taraneh, Khalilnezhad, Ahad, Jamshidi, Hamidreza, Amani, Davar“…Therefore, if our results are approved in the future, umbelliprenin can be an appropriate candidate for developing treatments against different cancers.…”
Publicado 2016
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134439“…These older surgical candidates usually ask the surgeon whether it would be safe to undergo surgery. …”
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134440por de Kunder, Suzanne L., Rijkers, Kim, van Kuijk, Sander M. J., Evers, Silvia M. A. A., de Bie, Rob A., van Santbrink, Henk“…A total of 144 patients over 18 years old with symptomatic single level lumbar degenerative, isthmic or iatrogenic spondylolisthesis whom are candidates for LIF (lumbar interbody fusion) surgery through a posterior approach will be randomly allocated to TLIF or PLIF. …”
Publicado 2016
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