“…PURPOSE: The PAX6 gene was first described as a candidate for human aniridia. However, PAX6 expression is not restricted to the eye and it appears to be crucial for brain development. …”
Enlace del recurso
Enlace del recurso

“…Accordingly, MYH9 was further explored in these studies as the leading candidate gene responsible for the MALD signal. Dense mapping of MYH9 identified individual single nucleotide polymorphisms (SNPs) and sets of such SNPs grouped as haplotypes that were found to be highly associated with a large and important group of ESKD risk phenotypes, which as a consequence were designated as MYH9-associated nephropathies (Bostrom and Freedman 2010). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, a set of more than 15 candidate transcripts are proposed to be potential components of the salt overly sensitive (SOS) pathway in chickpea. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this way we can obtain a zone/cluster candidate composed of a number of non necessarily connected regions. …”
Enlace del recurso

“…The final CC substrings chosen (Table 1) represented over 56% of visits in the candidate record dataset. Over 334,000 BioSense patient records were evaluated, and SMEs reviewed the 32 ICD-9-CM codes that co-occurred most commonly in visits containing oral health-related ICD-9-CM codes to determine which co-occurring ICD-9-CM codes (white list, Table 1) could be present and still maintain the main reason for the visit as an oral health-related problem. …”
Enlace del recurso

“…This allowed us to conduct an RNAi and mutation screen for genes that control the signaling (block non-random distributions) and several candidates have been identified. To directly test the notion that signaling of genotoxic damage occurs, we conducted experiments with alpha particles collimated through slits in metal foils and showed that genotoxic damage could be expressed many cell diameters away from a partial body exposure site. …”
Enlace del recurso
Enlace del recurso

“…HLA-B46 arose in mongoloids and remains largely limited to Chinese so the question arises as to whether the hominin candidate segment indicates an eastward trek of Homo neanderthalensis or the survival of much earlier Homo erectus? …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interestingly, a comprehensive collection of SARS-CoVs in which these motifs have been modified elicited full and long-term protection even in old mice, making those deletion mutants promising vaccine candidates. These data indicate that despite its small size, E protein drastically influences the replication of CoVs and their pathogenicity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The recurring nature of disease makes IBD patients ideal candidates for patient-engaged care that is centered on enhanced self-management and improved doctor-patient communication. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To explore mechanisms underlying RA-persistence, we performed a candidate gene study. We hypothesized that variants associating with lack of radiographic progression also associate with DMARD-free sustained remission. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The miRNA profiles of MaSCs, BCSCs and breast cancer MCF-7 cells were compared to obtain the candidate miRNAs that may regulate breast tumorigenesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Blood sample was got from the candidates before and after treatment. The plasma concentration of 5-HT was measured by ELISA. …”
Enlace del recurso
Enlace del recurso

“…Top regulated genes (≥2 fold change) by both treatments (FBP2, UCP2, TIEG2, ANGPTL4, ALDH1L2) are potential candidate genes for milk fat traits. Involvement of SCP2, PDK4, NQO1, F2RL1, DBI, CPT1A, CNTFR, CALB1, ACADVL, SPTLC3, PIK3CG, PIGZ, ADORA2B, TRIB3, HPGD, IGFBP2 and TXN in FA/lipid metabolism in dairy cows is being reported for the first time. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Compared to no vaccination, routine pediatric EV71 vaccination would be very cost-effective in China if the cost of immunization (including all logistical, procurement, and administration costs needed to confer 5 y of vaccine protection) is below US$12.0–US$18.3, depending on the choice of vaccine among the three candidates. Given that the annual number of births in China has been around 16 million in recent years, the annual costs for routine pediatric EV71 vaccination at this cost range should not exceed US$192–US$293 million. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Extensive medical examinations were carried out before the expedition, during the selection of candidates, and after returning, and particular functions were monitored during the entire stay in Antarctica. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Improvements in surgical techniques might result in restoration of knee function to the same level as ACL injured knees. Candidates for PCL reconstruction, could be informed about these results during the decision making process. …”
Enlace del recurso
Enlace del recurso

“…The findings offer a clinically applicable donor selection strategy that can help control cGVHD without affecting the risk of relapse and/or identify patients at a high risk of developing cGVHD as potential candidates for preemptive therapy. The findings also affirm the beneficial effect of one or more missing inhibitory KIR ligands in the recipient in reducing relapse and improving a relapse free survival in unrelated donor transplants.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To further confirm the linkage and reveal the genetic effects of these four candidate genes on milk fatty acid composition, genetic polymorphisms were identified and genotype-phenotype associations were performed in a Chinese Holstein cattle population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our data suggest that nCRT followed by LE may be considered as an organ-preserving alternative in carefully selected patients with clinically-staged T2N0 tumours who refuse, or are not candidates for, transabdominal resection.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: To assess the rates and predictors of traversing steps essential to good medical care for chronic migraine, including: (1) medical consultation, (2) accurate diagnosis, and (3) minimal pharmacologic treatment. Candidate predictors included socioeconomic, demographic, and headache‐specific variables. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso