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1401“…METHODS: Narrative review of cervical (pre)cancer candidate biomarkers from cervicovaginal fluid, is based on a detailed review of the literature. …”
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1402“…OBJECTIVE: To evaluate the eligibility of female-to-male (FtM) transgender people as donor candidates with regard to histologic, surgical, and social aspects. …”
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1403por Bal, Jyotiranjan, Luong, Nguyen Ngoc, Park, Jisang, Song, Ki-Duk, Jang, Yong-Suk, Kim, Dae-Hyuk“…The current study used a mouse model to explore the immunogenicity of an oral dengue vaccine candidate prepared using whole recombinant yeast cells (WC) and cell-free extracts (CFE) from cells expressing recombinant Escherichia coli heat-labile toxin protein B-subunit (LTB) fused to the consensus dengue envelope domain III (scEDIII). …”
Publicado 2018
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1404por Kiss, Lóránd, Duke, Anna, Kovacs, Kristof, Barcza, Tibor, Kiss, Márton, Petrikovics, Ilona, Thompson, David E.“…BACKGROUND: Dimethyl trisulfide (DMTS) is a highly lipid-soluble cyanide (CN) antidote candidate molecule. In prior studies with various US FDA-approved co-solvents, surfactants, and their combinations, aqueous solutions containing 15% polysorbate 80 (Poly80) were found to effectively solubilize DMTS in formulations for intramuscular administration. …”
Publicado 2017
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1406por Méndez, Yanira, Chang, Janoi, Humpierre, Ana R., Zanuy, Abel, Garrido, Raine, Vasco, Aldrin V., Pedroso, Jessy, Santana, Darielys, Rodríguez, Laura M., García-Rivera, Dagmar, Valdés, Yury, Vérez-Bencomo, Vicente, Rivera, Daniel G.“…For the first time, oxo- and carboxylic acid-functionalized polysaccharides could be either independently or simultaneously conjugated to immunogenic proteins by means of the Ugi-multicomponent reaction, thus leading to mono- or multivalent unimolecular glycoconjugates as vaccine candidates. Despite the high molecular weight of the two or three reacting biomolecules, the multicomponent bioconjugation proved highly efficient and reproducible. …”
Publicado 2018
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1407“…In the present study, we employed Hershberger assay to determine possible androgenic or antiandrogenic activities of three di-2-ethylhexyl phthalate (DEHP) substitute candidates. The assay was carried out using immature castrated Sprague–Dawley male rats. …”
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1409“…Furthermore, drugs including adenosine-5′-diphosphate may be novel drug candidates to treat patients with ALI.…”
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1411por Joachim, Rose B, Altschuler, Gabriel M, Hutchinson, John N, Wong, Hector R, Hide, Winston A, Kobzik, Lester“…Pathway‐centric Pathprint‐PDN is a powerful new way to identify drug candidates for intervention against sepsis and provides direct insight into pathways that may determine survival.…”
Publicado 2018
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1412por do Nascimento de Oliveira, Valzimeire, Lima-Neto, Abelardo Barbosa Moreira, van Tilburg, Maurício Fraga, de Oliveira Monteiro-Moreira, Ana Cristina, Duarte Pinto Lobo, Marina, Rondina, Davide, Fernandes, Virgínia Oliveira, Montenegro, Ana Paula Dias Rangel, Montenegro, Renan Magalhães, Guedes, Maria Izabel FlorindoEnlace del recurso
Publicado 2018
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1413por Hossain, Mohammad Uzzal, Keya, Chaman Ara, Das, Keshob Chandra, Hashem, Abu, Omar, Taimur Md., Khan, Md. Arif, Rakib-Uz-Zaman, S. M., Salimullah, Md.“…Toxicity assessment and drug score confirmed the effectiveness of these drug candidates. This in silico research might greatly facilitate the wet lab experiments to develop vaccine and drug against WNV.…”
Publicado 2018
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1414por BARRETO, Bruno Leandro de Melo, LIMA, Jones Silva, de ALBUQUERQUE, Diogo Barbosa, KREIMER, Flavio, FERRAZ, Álvaro Antonio Bandeira, CAMPOS, Josemberg Marins“…AIM: To evaluate the physical activity level of candidates to bariatric surgery and its relation with quality of life and body image, when patients are encouraged weekly by personal trainers. ()) Method: This is a prospective, interventional and longitudinal study with quantitative analysis. …”
Publicado 2018
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1415por Nallagangula, Krishna Sumanth, Lakshmaiah, V, Muninarayana, C, Deepa, KV, Shashidhar, KN“…Prioritization of candidates identified is a prerequisite for validation regimen. …”
Publicado 2018
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1417por Yang, Xiu-Lian, Li, Hai-Yan, Yue, Yuan-Zheng, Ding, Wen-Jie, Xu, Chen, Shi, Ting-Ting, Chen, Gong-Wei, Wang, Liang-Gui“…About 47.43% of the unigenes (64,795) could be annotated in the NCBI non-redundant protein database. A number of candidate genes were identified in the terpenoid metabolic pathways and 1327 transcription factors (TFs), which showed differential expression patterns among the floral scent formation stages, were also identified, especially OfMYB1, OfMYB6, OfWRKY1, and OfWRKY3, which could play critical roles in the floral scent formation. …”
Publicado 2018
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1418“…These data demonstrate that NgoΦfil phage particles can induce antibodies with anti-gonococcal activity and may be a candidate for vaccine development.…”
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1420“…This process is however laborious, particularly if the experiment is performed in a non-model species, and the statistical significance of the inferred candidates is typically unknown. RESULTS: This paper introduces QTLSearch, a method and software tool to search for candidate causal genes in QTL studies by combining Gene Ontology annotations across many species, leveraging hierarchical orthologous groups. …”
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