LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

por Nguyen, Hannah, Allali-Hassani, Abdellah, Antonysamy, Stephen, Chang, Shawn, Chen, Lisa Hong, Curtis, Carmen, Emtage, Spencer, Fan, Li, Gheyi, Tarun, Li, Fengling, Liu, Shichong, Martin, Joseph R., Mendel, David, Olsen, Jonathan B., Pelletier, Laura, Shatseva, Tatiana, Wu, Song, Zhang, Feiyu Fred, Arrowsmith, Cheryl H., Brown, Peter J., Campbell, Robert M., Garcia, Benjamin A., Barsyte-Lovejoy, Dalia, Mader, Mary, Vedadi, Masoud
Publicado 2015

RIPOSTE: a framework for improving the design and analysis of laboratory-based research

por Masca, Nicholas GD, Hensor, Elizabeth MA, Cornelius, Victoria R, Buffa, Francesca M, Marriott, Helen M, Eales, James M, Messenger, Michael P, Anderson, Amy E, Boot, Chris, Bunce, Catey, Goldin, Robert D, Harris, Jessica, Hinchliffe, Rod F, Junaid, Hiba, Kingston, Shaun, Martin-Ruiz, Carmen, Nelson, Christopher P, Peacock, Janet, Seed, Paul T, Shinkins, Bethany, Staples, Karl J, Toombs, Jamie, Wright, Adam KA, Teare, M Dawn
Publicado 2015

Mammographic density and breast cancer in women from high risk families

por Ramón y Cajal, Teresa, Chirivella, Isabel, Miranda, Josefa, Teule, Alexandre, Izquierdo, Ángel, Balmaña, Judith, Sánchez-Heras, Ana Beatriz, Llort, Gemma, Fisas, David, Lope, Virginia, Hernández-Agudo, Elena, Juan-Fita, María José, Tena, Isabel, Robles, Luis, Guillén-Ponce, Carmen, Pérez-Segura, Pedro, Luque-Molina, Mari Sol, Hernando-Polo, Susana, Salinas, Mónica, Brunet, Joan, Salas-Trejo, María Dolores, Barnadas, Agustí, Pollán, Marina
Publicado 2015

Validating prediction scales of type 2 diabetes mellitus in Spain: the SPREDIA-2 population-based prospective cohort study protocol

por Salinero-Fort, Miguel Ángel, de Burgos-Lunar, Carmen, Mostaza Prieto, José, Lahoz Rallo, Carlos, Abánades-Herranz, Juan Carlos, Gómez-Campelo, Paloma, Laguna Cuesta, Fernando, Estirado De Cabo, Eva, García Iglesias, Francisca, González Alegre, Teresa, Fernández Puntero, Belén, Montesano Sánchez, Luis, Vicent López, David, Cornejo Del Río, Víctor, Fernández García, Pedro J, Sabín Rodríguez, Concesa, López López, Silvia, Patrón Barandío, Pedro
Publicado 2015

‘Candidatus Liberibacter asiaticus’, Causal Agent of Citrus Huanglongbing, Is Reduced by Treatment with Brassinosteroids

por Canales, Eduardo, Coll, Yamilet, Hernández, Ingrid, Portieles, Roxana, Rodríguez García, Mayra, López, Yunior, Aranguren, Miguel, Alonso, Eugenio, Delgado, Roger, Luis, Maritza, Batista, Lochy, Paredes, Camilo, Rodríguez, Meilyn, Pujol, Merardo, Ochagavia, María Elena, Falcón, Viviana, Terauchi, Ryohei, Matsumura, Hideo, Ayra-Pardo, Camilo, Llauger, Raixa, Pérez, María del Carmen, Núñez, Mirian, Borrusch, Melissa S., Walton, Jonathan D., Silva, Yussuan, Pimentel, Eulogio, Borroto, Carlos, Borrás-Hidalgo, Orlando
Publicado 2016

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

por Lindau, Alexandra, Härdtner, Carmen, Hergeth, Sonja P., Blanz, Kelly Daryll, Dufner, Bianca, Hoppe, Natalie, Anto-Michel, Nathaly, Kornemann, Jan, Zou, Jiadai, Gerhardt, Louisa M. S., Heidt, Timo, Willecke, Florian, Geis, Serjosha, Stachon, Peter, Wolf, Dennis, Libby, Peter, Swirski, Filip K., Robbins, Clinton S., McPheat, William, Hawley, Shaun, Braddock, Martin, Gilsbach, Ralf, Hein, Lutz, von zur Mühlen, Constantin, Bode, Christoph, Zirlik, Andreas, Hilgendorf, Ingo
Publicado 2016

Diversity, structure and convergent evolution of the global sponge microbiome

por Thomas, Torsten, Moitinho-Silva, Lucas, Lurgi, Miguel, Björk, Johannes R., Easson, Cole, Astudillo-García, Carmen, Olson, Julie B., Erwin, Patrick M., López-Legentil, Susanna, Luter, Heidi, Chaves-Fonnegra, Andia, Costa, Rodrigo, Schupp, Peter J., Steindler, Laura, Erpenbeck, Dirk, Gilbert, Jack, Knight, Rob, Ackermann, Gail, Victor Lopez, Jose, Taylor, Michael W., Thacker, Robert W., Montoya, Jose M., Hentschel, Ute, Webster, Nicole S.
Publicado 2016

A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss

por Servián‐Morilla, Emilia, Takeuchi, Hideyuki, Lee, Tom V, Clarimon, Jordi, Mavillard, Fabiola, Area‐Gómez, Estela, Rivas, Eloy, Nieto‐González, Jose L, Rivero, Maria C, Cabrera‐Serrano, Macarena, Gómez‐Sánchez, Leonardo, Martínez‐López, Jose A, Estrada, Beatriz, Márquez, Celedonio, Morgado, Yolanda, Suárez‐Calvet, Xavier, Pita, Guillermo, Bigot, Anne, Gallardo, Eduard, Fernández‐Chacón, Rafael, Hirano, Michio, Haltiwanger, Robert S, Jafar‐Nejad, Hamed, Paradas, Carmen
Publicado 2016

A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: Results from the IMMEnSE consortium and meta-analysis

por Ríos-Tamayo, Rafael, Lupiañez, Carmen Belén, Campa, Daniele, Hielscher, Thomas, Weinhold, Niels, Martínez-López, Joaquin, Jerez, Andrés, Landi, Stefano, Jamroziak, Krzysztof, Dumontet, Charles, Wątek, Marzena, Lesueur, Fabienne, Reis, Rui Manuel, Marques, Herlander, Jurczyszyn, Artur, Vogel, Ulla, Buda, Gabriele, García-Sanz, Ramón, Orciuolo, Enrico, Petrini, Mario, Vangsted, Annette J, Gemignani, Federica, Försti, Asta, Goldschmidt, Hartmut, Hemminki, Kari, Canzian, Federico, Jurado, Manuel, Sainz, Juan
Publicado 2016

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

por Nagy, Reka, Boutin, Thibaud S., Marten, Jonathan, Huffman, Jennifer E., Kerr, Shona M., Campbell, Archie, Evenden, Louise, Gibson, Jude, Amador, Carmen, Howard, David M., Navarro, Pau, Morris, Andrew, Deary, Ian J., Hocking, Lynne J., Padmanabhan, Sandosh, Smith, Blair H., Joshi, Peter, Wilson, James F., Hastie, Nicholas D., Wright, Alan F., McIntosh, Andrew M., Porteous, David J., Haley, Chris S., Vitart, Veronique, Hayward, Caroline
Publicado 2017

Seasonal variability in clinical care of COPD outpatients: results from the Andalusian COPD audit

por López-Campos, Jose Luis, Abad Arranz, Maria, Calero-Acuña, Carmen, Romero-Valero, Fernando, Ayerbe-García, Ruth, Hidalgo-Molina, Antonio, Aguilar-Pérez-Grovas, Ricardo I, García-Gil, Francisco, Casas-Maldonado, Francisco, Caballero-Ballesteros, Laura, Sánchez-Palop, María, Pérez-Tejero, Dolores, Segado Soriano, Alejandro, Calvo-Bonachera, Jose, Hernández-Sierra, Bárbara, Doménech, Adolfo, Arroyo-Varela, Macarena, González-Vargas, Francisco, Cruz-Rueda, Juan J
Publicado 2017

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

por Mohr, Sebastian, Doebele, Carmen, Comoglio, Federico, Berg, Tobias, Beck, Julia, Bohnenberger, Hanibal, Alexe, Gabriela, Corso, Jasmin, Ströbel, Philipp, Wachter, Astrid, Beissbarth, Tim, Schnütgen, Frank, Cremer, Anjali, Haetscher, Nadine, Göllner, Stefanie, Rouhi, Arefeh, Palmqvist, Lars, Rieger, Michael A., Schroeder, Timm, Bönig, Halvard, Müller-Tidow, Carsten, Kuchenbauer, Florian, Schütz, Ekkehard, Green, Anthony R., Urlaub, Henning, Stegmaier, Kimberly, Humphries, R. Keith, Serve, Hubert, Oellerich, Thomas
Publicado 2017

Diagnosis features of pediatric Gaucher disease patients in the era of enzymatic therapy, a national-base study from the Spanish Registry of Gaucher Disease

por Andrade-Campos, Marcio, Alfonso, Pilar, Irun, Pilar, Armstrong, Judith, Calvo, Carmen, Dalmau, Jaime, Domingo, Maria-Rosario, Barbera, Jose-Luis, Cano, Horacio, Fernandez-Galán, Maria-Angeles, Franco, Rafael, Gracia, Inmaculada, Gracia-Antequera, Miguel, Ibañez, Angela, Lendinez, Francisco, Madruga, Marcos, Martin-Hernández, Elena, O’Callaghan, Maria del Mar, del Soto, Alberto Pérez, del Prado, Yolanda Ruiz, Sancho-Val, Ignacio, Sanjurjo, Pablo, Pocovi, Miguel, Giraldo, Pilar
Publicado 2017

Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia

por Knittel, Gero, Rehkämper, Tim, Korovkina, Darya, Liedgens, Paul, Fritz, Christian, Torgovnick, Alessandro, Al-Baldawi, Yussor, Al-Maarri, Mona, Cun, Yupeng, Fedorchenko, Oleg, Riabinska, Arina, Beleggia, Filippo, Nguyen, Phuong-Hien, Wunderlich, F. Thomas, Ortmann, Monika, Montesinos-Rongen, Manuel, Tausch, Eugen, Stilgenbauer, Stephan, P. Frenzel, Lukas, Herling, Marco, Herling, Carmen, Bahlo, Jasmin, Hallek, Michael, Peifer, Martin, Buettner, Reinhard, Persigehl, Thorsten, Reinhardt, H. Christian
Publicado 2017

DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders

por Berdasco, María, Gómez, Antonio, Rubio, Marcos J., Català-Mora, Jaume, Zanón-Moreno, Vicente, Lopez, Miguel, Hernández, Cristina, Yoshida, Shigeo, Nakama, Takahito, Ishikawa, Keijiro, Ishibashi, Tatsuro, Boubekeur, Amina M., Louhibi, Lotfi, Pujana, Miguel A, Sayols, Sergi, Setien, Fernando, Corella, Dolores, de Torres, Carmen, Parareda, Andreu, Mora, Jaume, Zhao, Ling, Zhang, Kang, Lleonart, Matilde E., Alonso, Javier, Simó, Rafael, Caminal, Josep M., Esteller, Manel
Publicado 2017

The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis

por Alonso-Molero, Jéssica, González-Donquiles, Carmen, Palazuelos, Camilo, Fernández-Villa, Tania, Ramos, Elena, Pollán, Marina, Aragonés, Nuria, Llorca, Javier, Henar Alonso, M., Tardón, Adonina, Amiano, Pilar, Moleon, José Juan Jiménez, Pérez, Rosana Peiró, Capelo, Rocío, Molina, Antonio J., Acebo, Inés Gómez, Guevara, Marcela, Gómez, Beatriz Pérez, Lope, Virginia, Huerta, José María, Castaño-Vinyals, Gemma, Kogevinas, Manolis, Moreno, Victor, Martín, Vicente
Publicado 2017

Transition structures and timing of transfer from paediatric to adult-based care after kidney transplantation in Germany: a qualitative study

por Prüfe, Jenny, Dierks, Marie-Luise, Bethe, Dirk, Oldhafer, Martina, Müther, Silvia, Thumfart, Julia, Feldkötter, Markus, Büscher, Anja, Sauerstein, Katja, Hansen, Matthias, Pohl, Martin, Drube, Jens, Thiel, Florian, Rieger, Susanne, John, Ulrike, Taylan, Christina, Dittrich, Katalin, Hollenbach, Sabine, Klaus, Günter, Fehrenbach, Henry, Kranz, Birgitta, Montoya, Carmen, Lange-Sperandio, Bärbel, Ruckenbrod, Bettina, Billing, Heiko, Staude, Hagen, Brunkhorst, Reinhard, Rusai, Krisztina, Pape, Lars, Kreuzer, Martin
Publicado 2017

Global cancer control: responding to the growing burden, rising costs and inequalities in access

por Prager, Gerald W, Braga, Sofia, Bystricky, Branislav, Qvortrup, Camilla, Criscitiello, Carmen, Esin, Ece, Sonke, Gabe S, Martínez, Guillem Argilés, Frenel, Jean-Sebastian, Karamouzis, Michalis, Strijbos, Michiel, Yazici, Ozan, Bossi, Paolo, Banerjee, Susana, Troiani, Teresa, Eniu, Alexandru, Ciardiello, Fortunato, Tabernero, Josep, Zielinski, Christoph C, Casali, Paolo G, Cardoso, Fatima, Douillard, Jean-Yves, Jezdic, Svetlana, McGregor, Keith, Bricalli, Gracemarie, Vyas, Malvika, Ilbawi, André
Publicado 2018

Chromothripsis in Acute Myeloid Leukemia: biological features and impact on survival

por Fontana, Maria Chiara, Marconi, Giovanni, Milosevic Feenstra, Jelena D., Fonzi, Eugenio, Papayannidis, Cristina, Ghelli Luserna di Rorá, Andrea, Padella, Antonella, Solli, Vincenza, Franchini, Eugenia, Ottaviani, Emanuela, Ferrari, Anna, Baldazzi, Carmen, Testoni, Nicoletta, Iacobucci, Ilaria, Soverini, Simona, Haferlach, Torsten, Guadagnuolo, Viviana, Semerad, Lukas, Doubek, Michael, Steurer, Michael, Racil, Zdenek, Paolini, Stefania, Manfrini, Marco, Cavo, Michele, Simonetti, Giorgia, Kralovics, Robert, Martinelli, Giovanni
Publicado 2017

Circulating microRNAs as biomarkers of disease and typification of the atherothrombotic status in antiphospholipid syndrome

por Pérez-Sánchez, Carlos, Arias-de la Rosa, Iván, Aguirre, María Ángeles, Luque-Tévar, María, Ruiz-Limón, Patricia, Barbarroja, Nuria, Jiménez-Gómez, Yolanda, Ábalos-Aguilera, María Carmen, Collantes-Estévez, Eduardo, Segui, Pedro, Velasco, Francisco, Herranz, María Teresa, Lozano-Herrero, Jesús, Hernandez-Vidal, María Julia, Martínez, Constantino, González-Conejero, Rocío, Radin, Massimo, Sciascia, Savino, Cecchi, Irene, Cuadrado, María José, López-Pedrera, Chary
Publicado 2018