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21por Zhao, Hangfen, Liu, Huaying, Qi, Weilin, Liu, Wei, Ye, Lingna, Cao, Qian, Ge, Xiaolong, Zhou, Wei, Wang, Xianfa“…ROC curves showed that the cutoff value for the CAR was 3.25. Patients with a CAR ≥ 3.25 had more complications (P < 0.001), a longer postoperative stay (15.5 ± 0.6 d vs. 9.0 ± 0.2 d, P < 0.001), and more surgical site infections (48.2% vs. 5.7%, P < 0.001) than those with a CAR < 3.25. …”
Publicado 2021
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22por Ai, Xinbo, Chen, Yuping, Qian, Jiajian, Zhou, Bin, Wang, Zhenjiang, Zhang, Yanjun, Li, Aimin, Gong, Feiyue, Pan, Wensheng, Shen, Bo, Liu, Side“…Patients present with CAR ≥3.33, Oakland score ≥12, and histopathological fibrin thrombi were independent risk factors. …”
Publicado 2021
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23por Cai, Wenxiang, Song, Weichen, Liu, Zhe, Maharjan, Dhruba Tara, Liang, Jisheng, Lin, Guan Ning“…Among these cell types, astrocyte, pericyte, and PAX6 cells were found to have a higher proportion in SCZ patients (astrocyte: SCZ = 0.163, control = 0.145, P.adj = 4.9 × 10(−4), effect size = 0.478; pericyte: SCZ = 0.057, control = 0.066, P.adj = 1.1 × 10(−4), effect size = 0.519; PAX6: SCZ = 0.014, control = 0.011, P.adj = 0.014, effect size = 0.377), while the L5/6_IT_CAR3 cells and LAMP5 cells are the exact opposite (L5/6_IT_Car3: SCZ = 0.102, control = 0.108, P.adj = 0.016, effect size = 0.369; LAMP5: SCZ = 0.057, control = 0.066, P.adj = 2.2 × 10(−6), effect size = 0.617). …”
Publicado 2022
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24“…We trained our models on an open-source dataset (ApolloCar3D). Our method outperforms all published solutions in terms of 6 degrees of freedom error (6 DoF err).…”
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25por Kappes, Lucy, Amer, Ruba L., Sommerlatte, Sabine, Bashir, Ghada, Plattfaut, Corinna, Gieseler, Frank, Gemoll, Timo, Busch, Hauke, Altahrawi, Abeer, Al-Sbiei, Ashraf, Haneefa, Shoja M., Arafat, Kholoud, Schimke, Lena F., Khawanky, Nadia El, Schulze-Forster, Kai, Heidecke, Harald, Kerstein-Staehle, Anja, Marschner, Gabriele, Pitann, Silke, Ochs, Hans D., Mueller, Antje, Attoub, Samir, Fernandez-Cabezudo, Maria J., Riemekasten, Gabriela, al-Ramadi, Basel K., Cabral-Marques, Otavio“…In vitro, Ambrisentan inhibited both spontaneous and induced migration/invasion capacity of different tumor cells (COLO-357 metastatic pancreatic adenocarcinoma, OvCar3 ovarian carcinoma, MDA-MB-231 breast adenocarcinoma, and HL-60 promyelocytic leukemia). …”
Publicado 2020
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26“…Based on Group 1 (400 cancer patients), the exploratory factor analysis identified a 23-item scale with six factors: value and esteem (five items, i.e., reconsider the meaning and purpose of life), independence and control (six items, i.e., private space), mental car (three items, i.e., vent negative emotions), disease care (three items, i.e., acquire knowledge about disease), belonging and companionship (three items, i.e., spend more time at home), and security (three items, i.e., living conditions be better). …”
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27“…The proteomics analysis revealed that a novel variant of anti-oxidant protein lung carbonyl reductase (car3) was uniquely and markedly elevated in the VIP KO mice. …”
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28“…Although CAIII expression was hypoxia-inducible, we did not observe binding of HIF-1α to select hypoxia-responsive-elements on Car3 promoter using genomic chromatin-immunoprecipitation. …”
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29por Pietrowski, Detlef, Grgic, Martina, Haslinger, Isabella, Marschalek, Julian, Schneeberger, Christian“…Compared to culturing granulosa cells alone, co-culturing human granulosa cells together with the ovarian cancer cell line OvCar-3 resulted in a significant increase in progesterone production (20.3 ng/ml versus 50.2 ng/ml; p < 0.01). …”
Publicado 2023
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30por Zhao, Xiaoyang, Sheng, Lei, Wang, Ling, Hong, Jie, Yu, Xiaohong, Sang, Xuezi, Sun, Qingqing, Ze, Yuguan, Hong, Fashui“…Furthermore, exposure to TiO(2) NPs resulted in the up-regulation of caspase-3, Nrbp2, and cytochrome c expression, and caused down-regulation of SOD, CAT, GPx, GST, GR, Cyp1b1, Car3, Bcl-2, Acaa2, and Axud1 expression in mouse testis. …”
Publicado 2014
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31por Zhang, Shuwen, Zhang, Yangzi, Zhou, Xiang, Fu, Xing, Michal, Jennifer J., Ji, Guoli, Du, Min, Davis, Jon F., Jiang, Zhihua“…The DE-APSs that were related to reduced and increased muscle mass were down-regulated in AMPKα1-KO mice, but up-regulated in AMPKα2-KO mice, respectively. Five genes: Car3 (carbonic anhydrase 3), Mylk4 (myosin light chain kinase family, member 4), Neb (nebulin), Obscn (obscurin) and Pfkm (phosphofructokinase, muscle) utilized different APSs with potentially antagonistic effects on muscle function. …”
Publicado 2018
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32por Carazo, Alejandro, Dusek, Jan, Holas, Ondrej, Skoda, Josef, Hyrsova, Lucie, Smutny, Tomas, Soukup, Tomas, Dosedel, Martin, Pávek, Petr“…TER stimulated CAR+A mutant translocation into the nucleus but neither LEF nor TER activated the CAR LBD, CAR3 variant or pregnane X receptor (PXR) in gene reporter assays. …”
Publicado 2018
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33por McMahon, Michael, Ding, Shaohong, Jimenez, Lourdes Acosta, Terranova, Remi, Gerard, Marie-Apolline, Vitobello, Antonio, Moggs, Jonathan, Henderson, Colin J., Wolf, C. Roland“…Additionally, two major splice isoforms of human CAR, CAR2 and CAR3, were inactive with almost all the agents tested. …”
Publicado 2019
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34“…Using the receiver operator characteristic curve for all‐cause mortality, the cut‐offs were calculated as NLR: 3.22, CAR: 3.25, IPI: 18.53 and MPI: 8367.82. In the univariable Cox hazard analysis, age, gender, smoking history, BVAS, FFS and over the cut‐off of each index showed statistical significance. …”
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35por Danielewski, Maciej, Zielińska, Sylwia, Matuszewska, Agnieszka, Słupski, Wojciech, Włodarczyk, Maciej, Jęśkowiak, Izabela, Wiatrak, Benita, Kowalski, Krzysztof, Jezierska-Domaradzka, Anna, Ziółkowski, Piotr, Szeląg, Adam, Nowak, Beata“…The study was conducted on sixty male rats randomly divided into six experimental groups: two control groups (a negative control group CON and a positive control group CAR); three groups receiving an investigational fraction of C. chinensis (1, 5, 10 mg/kg i.g.) named SC(1), SC(5), and SC(10), respectively; and a group receiving indomethacin (IND) (10 mg/kg i.g.) as a reference drug. …”
Publicado 2022
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36“…A 48-year-old male patient suffered from a car crash resulting in flexion-hyperextension injury of his head after being hit from behind by a moving car while waiting at a signal while driving a car. Three days after the car crash, he began to feel tinnitus in both ears and his tinnitus became aggravated with the passage of time. …”
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37Effects of Enactment in Episodic Memory: A Pilot Virtual Reality Study with Young and Elderly Adults“…Navigation in a virtual city was performed by 64 young and 64 older adults in one of four modes of exploration: (1) passive condition where participants were immersed as passengers of a virtual car [no interaction, no itinerary control (IC)], (2) IC (the subject chose the itinerary, but did not drive the car), (3) low, or (4) high navigation control (the subject just moved the car on rails or drove the car with a steering-wheel and a gas pedal on a fixed itinerary, respectively). …”
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38por Skoda, Josef, Dusek, Jan, Drastik, Martin, Stefela, Alzbeta, Dohnalova, Klara, Chalupsky, Karel, Smutny, Tomas, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr“…In gene reporter assays with CAR3 and in the TR-FRET assay, only diazepam significantly interacts with CAR-LBD. …”
Publicado 2020
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39por Jiang, Zhengtao, Liang, Huitong, Pan, Hanyu, Liang, Yue, Wang, Hua, Yang, Xinyi, Lu, Panpan, Zhang, Xiao, Yang, Jinlong, Zhang, Dengji, Shen, Xiaoting, Wang, Jing, Liang, Zhiming, Lin, Qinru, Wang, Yanan, Zhao, Lin, Zhong, Yangcheng, Lu, Hongzhou, Zhu, Huanzhang“…Here, we created HIV-specific CAR-T cells using human peripheral blood mononuclear cells (PBMCs) and a 3BNC117-DNR CAR (3BD CAR) construct that enables the expression of PD-1 dominant negative receptor (DNR) and the single-chain variable fragment of the HIV-1-specific broadly neutralizing antibody 3BNC117 to target native HIV envelope glycoprotein (Env). …”
Publicado 2021
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40por Isensee, Jörg, Witt, Henning, Pregla, Reinhard, Hetzer, Roland, Regitz-Zagrosek, Vera, Ruiz Noppinger, Patricia“…Cyp2b10), carbonic anhydrases (e.g. Car2 and Car3) and natriuretic peptides (e.g. Nppb) were identified with sex- and/or age-specific expression levels. …”
Publicado 2007
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