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  1. 1201
    “…Based on univariate analysis and the LASSO Cox model, five pyroptosis-related genes [including GADMA, interleukin-6 (IL-6), NLR pyrin domain-containing protein 6 (NLRP6), caspase-1 (CASP1), and caspase-9 (CASP9)], were obtained to calculate a risk score. …”
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    Pyroptosis-Related Signatures for Predicting Prognosis in Breast Cancer
  2. 1202
    “…By utilizing CRISPR-Cas9 gene edited CASP4/1, NLRP3 KO and ASC-def cells, caspase-4 activation was found to be independent of the canonical NLRP3 inflammasomes. …”
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    The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion
  3. 1203
    “…The expression of NEU1 was positively correlated with the expression of proliferation marker CDK2 and epithelial-mesenchymal transition marker CD44 and negatively correlated with the expression of apoptosis marker CASP3 and CASP8. Moreover, the expression level of NEU1 was related to the infiltration of immune cells in melanoma. …”
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    Sialidase NEU1 May Serve as a Potential Biomarker of Proliferation, Migration and Prognosis in Melanoma
  4. 1204
    “…RESULTS: A total of 28, 37, 36, 27, and 33 anti-OP targets of ARS, DHA, ART, ARM, and ARE were acquired. EGFR, EGFR, CASP3, MAPK8, and CASP3 act as the top 1 anti-OP targets of ARS, DHA, ART, ARM, and ARE, respectively. …”
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    Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking
  5. 1205
    “…As a result, we found that B cell infiltration ratio, CD4(+) T cells, as well as immune-related genes of TRIB3, CHGA, CASP7, LGALS4, LEP, NOX4, IL17A, and HSPD1 may be highly relevant with clinical outcome of colon cancer.…”
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    Immune-Related Prognostic Model in Colon Cancer: A Gene Expression-Based Study
  6. 1206
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    The Timing of Corticosteroid Injections following Knee Arthroscopy Influence Infection Risk
  7. 1207
    por Casadio, Rita
    Publicado 2003
    “…The course, co-supported (as last year) by the European Science Foundation program on Functional Genomics, focused mainly on hot topics in structural genomics, including recent CASP and CAPRI results, recent and promising genomewide predictions, protein–protein and protein–DNA interaction predictions and genome functional annotation. …”
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    The 4th Bologna Winter School: Hot Topics in Structural Genomics
  8. 1208
    “…Predicted structures submitted for CASP10 have been evaluated as molecular replacement models against the corresponding sets of structure factor amplitudes. …”
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    Local Error Estimates Dramatically Improve the Utility of Homology Models for Solving Crystal Structures by Molecular Replacement
  9. 1209
    “…Protein-protein interaction (PPI) analysis revealed that the core targets of BZD in treating CRC were AKT1, MYC, CASP3, ESR1, EGFR, HIF-1A, VEGFR, JUN, INS, and STAT3. …”
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    Mechanism of Bazhen decoction in the treatment of colorectal cancer based on network pharmacology, molecular docking, and experimental validation
  10. 1210
    “…A total of 6 hub target genes (AKT1, CASP3, PPARG, SIRT1, TNF and TP53) were identified using the Cytoscape-cytoHubba plugin. …”
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    Exploring the Potential Molecular Mechanism of Sijunzi Decoction in the Treatment of Non-Segmental Vitiligo Based on Network Pharmacology and Molecular Docking
  11. 1211
    “…No resistance was seen for echinocandins apart from one C. krusei strain showing an intermediate result for CASP. CONCLUSION: The study showed an overall high rate of non-albicans Candida, with the predominance of C. parapsilosis and C. glabrata, representing a therapeutic challenge. …”
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    Clinical and Microbiological Characteristics of Candidemia Cases in Saudi Arabia
  12. 1212
    “…Five primary candidate genes (CFLAR, CASP10, CASP8, FZD7 and BMPR2) were sequenced and no segregating variants identified. …”
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    Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)
  13. 1213
    “…The deep belief network is trained on several large datasets consisting of models from the Critical Assessment of Protein Structure Prediction (CASP) experiments, several publicly available datasets, and models generated by our in-house ab initio method. …”
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    DeepQA: improving the estimation of single protein model quality with deep belief networks
  14. 1214
    por Hou, Hongli, Xing, Weipeng, Li, Wuyin
    Publicado 2016
    “…B-cell chronic lymphocytic leukemia/lymphoma 2 was suppressed (P < 0.05), while cytochrome c, caspase 3 (CASP3) and CASP9 were activated (P < 0.01) by BRG1. …”
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    Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A
  15. 1215
    “…Reference to anatomical localization of tumor Del allele of NFKB1 and CASP8 were associated with more colon related incidents than rectosigmoid. …”
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    Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features
  16. 1216
    “…The OHT-induced release of cytokines and RGC death were significantly decreased in the retinas of Casp1(−/−)Casp4(11)(del), Panx1(−/−) and in Wild-type (WT) mice treated with the Panx1 inhibitor probenecid. …”
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    Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury
  17. 1217
    “…Moreover, a combined hMSC delivery increased motor neuron survival, maintained neuromuscular junctions in quadriceps femoris and substantially reduced the levels of proteins involved in necroptosis (Rip1, mixed lineage kinase‐like protein, cl‐casp8), apoptosis (cl‐casp 9) and autophagy (beclin 1). …”
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    A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1(G93A) Rats
  18. 1218
    “…To evaluate performances of DeepACLSTM, we conduct experiments on three publicly available datasets: CB513, CASP10 and CASP12. Results indicate that the performance of our method is superior to the state-of-the-art baselines on three publicly datasets. …”
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    DeepACLSTM: deep asymmetric convolutional long short-term memory neural models for protein secondary structure prediction
  19. 1219
    “…Activated Caspase-6 (Casp6) is associated with age-dependent cognitive impairment and Alzheimer disease (AD). …”
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    Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice
  20. 1220
    “…In sharp contrast, BMDCs from Casp1(−/−) mice exhibited reduced IL-1ß release following either of the three stimulants. …”
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    P2X7 Receptor Stimulation Is Not Required for Oxalate Crystal-Induced Kidney Injury
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