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1301por Junker, Theresa, Duus, Louise, Rasmussen, Benjamin S. B., Azawi, Nessn, Lund, Lars, Graumann, Ole, Nørgaard, Birgitte“…The quality assessment was performed using the Critical Appraisal Skills Programme (CASP) checklist for cohort studies and the CASP Randomized Controlled Trial Checklist. …”
Publicado 2022
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1302“…Two significant modules, which had higher scores, and 10 hub genes were chosen. Finally, caspase 3 (CASP3), and tumor protein P53 (TP53) were identified as core genes. …”
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1303por Bordin, Nicola, Dallago, Christian, Heinzinger, Michael, Kim, Stephanie, Littmann, Maria, Rauer, Clemens, Steinegger, Martin, Rost, Burkhard, Orengo, Christine“…The most recent method to be top ranked by the Critical Assessment of Structure Prediction (CASP) assessment, AlphaFold 2 (AF2), is capable of building structural models with an accuracy comparable to that of experimental structures. …”
Publicado 2023
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1304“…The weighted linear average of the spectral power density (SPD) profiles of each of the eight “precursor” proteins displayed remarkable congruence with the SPD profile of the terminal molecule (CASP-9) in the pathway. These results suggest that classic and complex signaling pathways in cells can also be expressed as combinations of resonance energies.…”
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1305“…We propose a fragment-free probabilistic graphical model, FUSION, for conformational sampling in continuous space and assess its accuracy using ‘blind’ protein targets with a length up to 250 residues from the CASP11 structure prediction exercise. The method reduces sampling bottlenecks, exhibits strong convergence, and demonstrates better performance than the popular fragment assembly method, ROSETTA, on relatively larger proteins with a length of more than 150 residues in our benchmark set. …”
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1306“…Evaluations are related on both benchmark and CASP target proteins. Structure ensembles subjected to the proposed approach and the source code of the proposed approach are publicly-available at the links provided in Section 1.…”
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1307“…Comparable results suggest the presence of significant perifollicular inflammatory infiltrates, such as lymphocytes and histiocytes, as well as the involvement of inflammatory genes, such as CASP7 and TNF, in the presentation of MPHL and FPHL. …”
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1308por Maltarić, Manuela, Ruščić, Paula, Kolak, Mirela, Bender, Darija Vranešić, Kolarić, Branko, Ćorić, Tanja, Hoejskov, Peter Sousa, Bošnir, Jasna, Kljusurić, Jasenka Gajdoš“…The results of the study indicate a positive correlation between adherence to the principles of the Mediterranean diet with CASP and self-perception of health, which the followers of the MD pattern predominantly rate as “very good” or “excellent” (37.05%) what is significantly different (p < 0.05) from individuals which do not follow the patterns of MD (21.55%). …”
Publicado 2023
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1309por Kuebart, Anne, Gross, Katharina, Ripkens, Jan-Joschua, Tenge, Theresa, Raupach, Annika, Schulz, Jan, Truse, Richard, Hof, Stefan, Marcus, Carsten, Vollmer, Christian, Bauer, Inge, Picker, Olaf, Herminghaus, Anna“…Forty Wistar rats were randomly divided into 4 groups: sepsis (colon ascendens stent peritonitis, CASP) without treatment as control, sepsis + pravastatin, sepsis + PPAR-α-blocker GW6471, and sepsis + pravastatin + GW6471. …”
Publicado 2023
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1310por Wei, Wei, Yao, Jiu-xiu, Zhang, Ting-ting, Wen, Jia-yu, Zhang, Zhen, Luo, Yi-miao, Cao, Yu, Li, Hao“…CONCLUSION: AKT1, HSP90AA1, SRC, HRAS, IGF1 and ALB, EGFR, CASP3 were core targets of BBR in the treatment of AD. …”
Publicado 2023
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1311por Li, Yujie, Zhang, Nannan, Peng, Xin, Ma, Wukai, Qin, Yuanxing, Yao, Xueming, Huang, Cong, Zhang, Xudong“…Topology analysis yields core key targets, such as TP53, INS, IL6, VEGFA, MYC, CASP3, ESR1, EGF, CCND1, PPARG, ERBB2, NFKBIA, TLR4, RELA, and CASP8, and the results of KEGG enrichment analysis showed that JSQS mainly works through pathways in cancer, phosphatidylinositol-3-kinaseRAC–serine/threonine-protein kinase signaling, and mitogen-activated protein kinase (MAPK) signaling pathway, and aryl hydrocarbon receptor nuclear translocator signaling pathway. …”
Publicado 2023
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1312por Yang, Mingyi, Zheng, Haishi, Su, Yani, Xu, Ke, Yuan, Qiling, Cai, Yongsong, Aihaiti, Yirixiati, Xu, Peng“…RESULTS: We obtained five PRGs (CHMP4C, BAK1, GSDMA, CASP1, and CASP6) that predicted OS prognosis and seven PRLncs (AC090559.1, AP003119.2, CARD8-AS1, AL390728.4, SATB2-AS1, AL133215.2, and AC009495.3) and one PRceRNA (CARD8-AS1-hsa-miR-21-5p-IL1B) that predicted OS prognosis and indicated characteristics of the OS immune microenvironment. …”
Publicado 2023
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1313“…This favourably compares with the best automated predictors at CASP6. CONCLUSION: Our final system for contact map prediction achieves state-of-the-art performances, and may provide valuable constraints for improved ab initio prediction of protein structures. …”
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1314por Castaño-Rodríguez, Natalia, Kaakoush, Nadeem O., Goh, Khean-Lee, Fock, Kwong Ming, Mitchell, Hazel M.“…CONCLUSIONS: Novel associations between polymorphisms in the NLR signalling pathway (CARD8, NLRP3, NLRP12, NLRX1, and CASP1) and GC were identified in Chinese individuals. …”
Publicado 2014
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1315por Peron, Isabela Haddad, Reichert-Lima, Franqueline, Busso-Lopes, Ariane Fidelis, Nagasako, Cristiane Kibune, Lyra, Luzia, Moretti, Maria Luiza, Schreiber, Angelica Zaninelli“…The in vitro antifungal susceptibility to amphotericin B (AMB), 5-flucytosine (5FC), fluconazole (FLC), itraconazole (ITC), voriconazole (VRC), caspofungin (CASP) was performed by broth microdilution methodology recommended by the Clinical and Laboratory Standards Institute documents (M27-A3 and M27-S4, CLSI). …”
Publicado 2016
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1316por Breunig, Christian, Pahl, Jens, Küblbeck, Moritz, Miller, Matthias, Antonelli, Daniela, Erdem, Nese, Wirth, Cornelia, Will, Rainer, Bott, Alexander, Cerwenka, Adelheid, Wiemann, Stefan“…MiR-519a-3p diminished the expression of its direct target genes for TRAIL-R2 (TNFRSF10B) and for caspase-8 (CASP8) and its indirect target gene for caspase-7 (CASP7), resulting in reduced sensitivity and tumor cell apoptosis in response to apoptotic stimuli. …”
Publicado 2017
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1317“…These results that CASP1, ALDH1A1 and PROS1 may be potential biomarkers for uterine leiomyomas. …”
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1318“…These tests were blindly performed on targets from the CASP11 dataset; and the results suggested that our models achieved comparable performance to contact predictors developed by groups that participated in CASP11. …”
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1319por Salimiaghdam, Nasim, Singh, Lata, Schneider, Kevin, Nalbandian, Angele, Chwa, Marilyn, Atilano, Shari R, Bao, Andrea, Kenney, M Cristina“…At 48 and 72 hours, levels of MMP and ROS decreased significantly with each antibiotic. BAX, BCL2-L13, CASP-7, CASP-9, SOD2 and GPX3 genes overexpressed by either antibiotics. …”
Publicado 2020
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1320“…Microarray analysis revealed altered gene expression: Genes mediating cell adhesion, division, DNA-binding, apoptosis (Casp3,Casp8), senescence (ASF1A,CENPA,FBXO31), and autophagy (ATG4D,ATG2A,SOGA1) were upregulated. …”
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