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  1. 1401
    “…RESULTS: In experiment 1, BA supplementation decreased caspase-3 (CASP3) (P < 0.001) and caspase-8 (CASP8) (P < 0.05) and increased occludin (OCLD) (P < 0.05) expression regardless of the challenge. …”
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    Modulations of genes related to gut integrity, apoptosis, and immunity underlie the beneficial effects of Bacillus amyloliquefaciens CECT 5940 in broilers fed diets with different protein levels in a necrotic enteritis challenge model
  2. 1402
    “…The study quality was evaluated with Critical Appraisal Skills Programme (CASP) appraisal checklists. RESULTS: Initial searching yielded 21,090 results with 42 studies meeting the inclusion criteria. …”
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    Effects of continuity of care on health outcomes among patients with diabetes mellitus and/or hypertension: a systematic review
  3. 1403
    “…Primary human hepatocytes could be sensitized to pyroptosis by pre-treatment with the ER-stress inducer tunicamycin and LPS. Casp11(–/–) mice treated with CCl(4) + LPS were significantly protected from multi-organ injury compared to wild-type CCl(4) + LPS. …”
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    The Lipopolysaccharide-Sensing Caspase(s)-4/11 Are Activated in Cirrhosis and Are Causally Associated With Progression to Multi-Organ Injury
  4. 1404
    “…Through protein–protein interaction analysis, TP53, CASP8, CASP3, MYC, JUN and PTGS2 were identified as the key therapeutic targets. …”
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    Network pharmacology and molecular docking technology-based predictive study of the active ingredients and potential targets of rhubarb for the treatment of diabetic nephropathy
  5. 1405
    “…We evaluated biochemical factors [aminotransferases (ALT and AST), albumin, and bilirubin (TBIL) spectrophotometrically, caspase 8 (CASP8), p53, Bcl2 associated X protein (BAX), caspase 3 (CASP3), alpha-fetoprotein (AFP), cancer antigen 19.9 (CA19.9), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) using ELISA], and liver histopathologically. …”
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    Biochemical and pathophysiological improvements in rats with thioacetamide induced-hepatocellular carcinoma using aspirin plus vitamin C
  6. 1406
    “…Mtb-RNase J forms an active homodimer through the interactions between the β-CASP and the β-lactamase domain. Knockout of RNase J slows the growth rate and changes the colony morphologies and cell length in Mycobacterium smegmatis, which is restored by RNase J complementation. …”
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    Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism
  7. 1407
    por Litwin, Howard, Levinsky, Michal
    Publicado 2022
    “…Using data from the Survey of Health, Ageing and Retirement in Europe, we regressed three well-being measures (CASP, life satisfaction and Euro-D depressive symptoms) on indicators of personality and social network. …”
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    The Interplay of Personality Traits and Social Network Characteristics in the Subjective Well-Being of Older Adults
  8. 1408
    “…In late 2020, the results of CASP14, the 14th event in a series of competitions to assess the latest developments in computational protein structure-prediction methodology, revealed the giant leap forward that had been made by Google’s Deepmind in tackling the prediction problem. …”
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    Predicted models and CCP4
  9. 1409
    “…ZEPPI performance is evaluated through applications to experimentally determined complexes and to decoys from the CASP-CAPRI experiment. ZEPPI can be implemented on a proteome-wide scale as evidenced by calculations on millions of structural models of dimeric complexes in the E. coli and human interactomes found in the PrePPI database. …”
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    ZEPPI: proteome-scale sequence-based evaluation of protein-protein interaction models
  10. 1410
    “…The new method was used for ab initio predictions as part of CASP5. This work was presented at the Winter School in Bioinformatics, Bologna, Italy, 10–14 February 2003.…”
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    Ab Initio Protein Structure Prediction Using Pathway Models
  11. 1411
    “…The QMEAN server provides access to two scoring functions successfully tested at the eighth round of the community-wide blind test experiment CASP. The user can choose between the composite scoring function QMEAN, which derives a quality estimate on the basis of the geometrical analysis of single models, and the clustering-based scoring function QMEANclust which calculates a global and local quality estimate based on a weighted all-against-all comparison of the models from the ensemble provided by the user. …”
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    QMEAN server for protein model quality estimation
  12. 1412
    “…However, in vivo Mtb aerosol infection of Nlrp3(−/−), Casp-1(−/−), and WT mice showed no differences in pulmonary IL-1β production, bacterial burden, or long-term survival. …”
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    Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1
  13. 1413
    “…A recent study revealed that ES (embryonic stem) cell lines derived from the 129 murine strain carry an inactivating mutation within the caspase 11 gene (Casp4) locus [Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma and Dixit (2011) Nature 479, 117–121]. …”
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    An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1
  14. 1414
    “…By a second genome-wide association study, meta-analysis, and independent replication study, we have now identified 13 additional vitiligo-associated loci, including OCA2-HERC2, a region of 16q24.3 containing MC1R, a region of chromosome 11q21 near TYR, several immunoregulatory loci including IFIH1, CD80, CLNK, BACH2, SLA, CASP7, CD44, IKZF4, SH2B3, and a region of 22q13.2 where the causal gene remains uncertain. …”
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    Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo
  15. 1415
    por Roy, Ambrish, Yang, Jianyi, Zhang, Yang
    Publicado 2012
    “…In the recent community-wide CASP9 experiment, COFACTOR was ranked as the best method for protein–ligand binding site predictions. …”
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    COFACTOR: an accurate comparative algorithm for structure-based protein function annotation
  16. 1416
    “…We measured the effects of experimental sepsis on long-term immunological memory for a defined antigen: we induced colon ascendens stent peritonitis (CASP) 8 weeks after 2 rounds of immunization with ovalbumin. …”
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    Experimental Sepsis Impairs Humoral Memory in Mice
  17. 1417
    “…We first describe de novo blind structure predictions of unprecendented accuracy we made for two proteins in large families in the recent CASP11 blind test of protein structure prediction methods by incorporating residue–residue co-evolution information in the Rosetta structure prediction program. …”
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    Large-scale determination of previously unsolved protein structures using evolutionary information
  18. 1418
    “…Computer Assisted Synthesis Planning (CASP) has gained considerable interest as of late. …”
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    Datasets and their influence on the development of computer assisted synthesis planning tools in the pharmaceutical domain
  19. 1419
    “…The convergent LG beams can be effectively shaped by the CASPs produced.…”
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    Generating Convergent Laguerre-Gaussian Beams Based on an Arrayed Convex Spiral Phaser Fabricated by 3D Printing
  20. 1420
    “…These structures were characterized by high cellular diversity, proliferating cells and enrichment for BRCA1 and CASP8 mutations and predicted poor outcome in estrogen-receptor-positive disease. …”
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    Breast tumor microenvironment structures are associated with genomic features and clinical outcome
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