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1501“…The data were imported to Endnote; and to assess the quality of the articles, PRISMA and CASP were used. Finally, according to the inclusion criteria, the appropriate articles were selected. …”
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1502por Supper, Emmanuelle, Rudat, Saskia, Iyer, Vivek, Droop, Alastair, Wong, Kim, Spinella, Jean-François, Thomas, Patrick, Sauvageau, Guy, Adams, David J., Wong, Chi C.“…Here, we demonstrate that elevated levels of the anti-apoptotic factor, CASP8 and FADD-like apoptosis regulator (CFLAR), promotes apoptosis evasion in acute myeloid leukemia (AML) cells haploinsufficient for the cut-like homeobox 1 (CUX1) transcription factor, whose loss is associated with dismal clinical prognosis. …”
Publicado 2021
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1503A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effectspor Choquet, Hélène, Melles, Ronald B., Anand, Deepti, Yin, Jie, Cuellar-Partida, Gabriel, Wang, Wei, Hoffmann, Thomas J., Nair, K. Saidas, Hysi, Pirro G., Lachke, Salil A., Jorgenson, Eric“…Sex-stratified analyses identified CASP7 as an additional novel locus specific to women. …”
Publicado 2021
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1504por Brusilovsky, Michael, Rochman, Mark, Rochman, Yrina, Caldwell, Julie M., Mack, Lydia E., Felton, Jennifer M., Habel, Jeff E., Porollo, Aleksey, Pasare, Chandrashekhar, Rothenberg, Marc E.“…Inhibiting caspase 8 pharmacologically and deleting murine Il33 and Casp8 each attenuated allergic inflammation in vivo. …”
Publicado 2021
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1505“…Five genes (NLRP1, NOD1, NLRC4, CASP9, and PLCG1) were identified to construct a prognostic model. …”
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1506“…This review highlights several gene mutations with a high frequency or a strong influence associated with favorable or unfavorable aspects of prognosis—NOTCH1, FBXW7, PTEN, LOH6q, CASP8AP2, c-MYC, IL-7, CALM-AF10, and CDKN2A/B—and indicates that the actual incidence of mutations in T-ALL/LBL is much higher than currently recognized. …”
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1507“…CONCLUSION: AKT1, CDKN2A, ERBB2, and IL6 are common protein core of liver and pancreatic cancers, while STAT3, CASP3, NOTCH1, and CTNNB1 are possible differential proteins to discriminate these cancers.…”
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1508por Smieszek, Agnieszka, Marcinkowska, Klaudia, Pielok, Ariadna, Sikora, Mateusz, Valihrach, Lukas, Carnevale, Elaine, Marycz, Krzysztof“…Attenuated metabolism of Eca EPCs OB was related to increased expression of pro-apoptotic markers (CASP9, BAX, P53, P21), enhanced expression of OPN, PI3K, and AKT, simultaneously with decreased signaling stabilizing cellular homeostasis (including mitofusin, SIRT1, FOXP3). …”
Publicado 2022
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1509por Sharifi, Tahere, Shamsi Gooshki, Ehsan, Mosadeghrad, Ali Mohammad, Jaafaripooyan, Ebrahim“…Several keywords, including "patient rights", "patient bills of rights" and "patients rights’ charter" were searched bilingually in the databases of SID, Magiran, PubMed, Scopus, and Web of Science from 2010 to 2021, and then, following a three-tier screening using the Critical Appraisal Skills Program (CASP) checklists, 76 articles were extracted. The degree of compliance with the Patients' Rights Charter (PRC) in healthcare organizations was 60.88% on average. …”
Publicado 2021
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1510“…Additionally, five optimal hub target genes were screened including tumor protein P53 (TP53), interleukin-6 (IL-6), vascular endothelial growth factor-A (VEGF-A), caspase-3 (CASP-3), and estrogen receptor-1 (ESR-1). The interrelated network between active components of QLD and their potential targets was constructed. …”
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1511“…The appraisal of quality was conducted by using the Critical Appraisal Skills Programme (CASP) to fulfil the selected keywords. RESULTS: Occupational noise exposure not only affects the workers’ most common issues, such as heart rate, but also other physiological factors, such as blood pressure. …”
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1512por He, Yongze, Cai, Yuxiang, Liu, Jinsheng, Ding, Haixia, Li, Xiang, Tian, Sufang, Li, Zhiqiang“…We developed a six-gene PRG-based prognostic model, and the results have identified CASP4 as an effective marker for LGG prognosis predictions. …”
Publicado 2022
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1513“…(PS)(2) was evaluated for 47 comparative modeling targets in CASP6 (Critical Assessment of Techniques for Protein Structure Prediction). …”
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1514“…Two independent reviewers used the Critical Appraisal Skills Programme (CASP) to assess the quality. The interpretative synthesis implied permanent contrast and consensus among the authors, revealing four categories and one meta-theme. …”
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1515Publicado 2017“…We observed striking APOBEC mutagenesis patterns and identified SHKBP1, ERBB3, CASP8, HLA-A, and TGFBR2 as novel significantly mutated genes in cervical cancer. …”
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1516“…DeepContact significantly improves performance over previous methods, including in the CASP12 blind contact prediction task where we achieved top performance with another CNN-based approach. …”
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1517por Li, Miao, Tang, Hongyu, Hu, Yuanhao, Li, Songtao, Kang, Pan, Chen, Baihao, Li, Shaocong, Zhang, Meng, Wang, Haibin, Huo, Shaochuan“…Quercetin, lignans and kaempferol were identified as key components, and the key targets included Akt1, MAPKs, and CASP3. Subsequently, UPLC-MS/MS analysis confirmed the presence of components in THJGC for the treatment of osteoporosis. …”
Publicado 2023
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1518“…We show that tcasp8 (−) (/) (−) mice develop an age-dependent lethal lymphoproliferative and lymphoinfiltrative immune disorder characterized by lymphoadenopathy, splenomegaly, and accumulation of T cell infiltrates in the lungs, liver, and kidneys. Peripheral casp8 (−) (/) (−) T cells manifest activation marker up-regulation and are proliferating in the absence of any infection or stimulation. …”
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1519“…FLASH (FLICE-associated huge protein or CASP8AP2) is a large multifunctional protein that is involved in many cellular processes associated with cell death and survival. …”
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1520“…One of these, an interaction between CASP8-rs1045485 and alcohol consumption has been replicated, but others have not, including LSP1- rs3817198 and parity, and 1p11.2-rs11249433 and ever being parous. …”
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