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1641“…The search was performed systematically, and the 14 included studies were evaluated with Critical Appraisal Skills Programme checklist (CASP). We identified seven themes and a metaphor in a lines-of-argument synthesis, showing that contemplating help-seeking is a multidimensional phenomenon. …”
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1643“…The outstanding performance of AlphaFold2 in the recent Critical Assessment of protein Structure Prediction (CASP14) experiment demonstrates the remarkable power of deep learning in structure prediction. …”
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1644por Chang, Yun-Tsan, Ignatova, Desislava, Hoetzenecker, Wolfram, Pascolo, Steve, Fassnacht, Christina, Guenova, Emmanuella“…In the presence of CL, the double-stranded DNA breaks in malignant MF skin T cells increased significantly as well as the expression of the apoptotic gene CASP3. These data point toward an important effect of targeting CL on MF skin tumor T cells, which support CL use as an early cutaneous lymphoma treatment and can be of synergistic use, especially beneficial in the setting of combination skin-directed therapies for cutaneous T-cell lymphoma.…”
Publicado 2021
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1645“…The results displayed that the top ten compounds which belonged to the two broad categories, ginkgo flavonoids and proanthocyanidins, could interact closely with several important target proteins (CASP3, SOD2, MAPK1, HSPA4, and NQO1). This would be expected to lay a theoretical foundation for the deep development of Ginkgo biloba extract.…”
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1646por de Ridder, Denise, Aarts, Henk, Benjamins, Jeroen, Glebbeek, Marie‐Louise, Leplaa, Hidde, Leseman, Paul, Potgieter, Renske, Tummers, Lars, Zondervan‐Zwijnenburg, MariëlleEnlace del recurso
Publicado 2021
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1647“…Included studies were evaluated for quality according to the Critical Appraisal Skills Programme (CASP) checklists. RESULTS: Thirteen qualitative studies met the inclusion criteria and four main themes of barriers to midwives offering NPPM emerged: health system-related, health facility-related, health practitioner-related, and health consumer-related barriers. …”
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1648“…Furthermore, CS prevented the apoptosis of human lens epithelial cells induced by UVB lights by decreasing the gene expression of CASP3, ESR1, and TP53 and increasing the CRYAB gene expression. …”
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1649“…A three-gene PRG signature (BNIP3, CASP9, and CAPN1) was identified, and BNIP3 was identified as the core gene. …”
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1650por Coelho, Aline Meireles, Queiroz, Isabela Ferreira, Perucci, Luiza Oliveira, de Souza, Melina Oliveira, Lima, Wanderson Geraldo, Talvani, André, Costa, Daniela Caldeira“…The NAC+P20 and NAC+P40 groups showed a reduced area of necrosis, MMP-9 activity, and Casp-1 expression. Furthermore, the NAC+P20 group was the only treatment that reduced alanine aminotransferase (ALT) and increased the levels of sulfhydryl groups (-SH). …”
Publicado 2022
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1652por Liu, Xue, Cui, Shiyao, Dan, Caiyun, Li, Wenle, Xie, Hongqing, Li, Conghui, Shi, Liangen“…Molecular docking elucidated the binding conformation and mechanism of the primary active components (Osmundacetone and hispidin) to the core targets CASP3, PARP1 and TP53. In addition, potential molecular mechanisms of PBP predicted by network pharmacology analysis were validated in vitro. …”
Publicado 2022
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1653“…The studies were appraised using two quality appraisal tools including the critical appraisal skills programme (CASP) for cohort studies and the Joanna Briggs Institute (JBI) checklist tool for cross-sectional studies. …”
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1654por Eichwald, Tuany, Solano, Alexandre Francisco, Souza, Jennyffer, de Miranda, Taís Browne, Carvalho, Liebert Bernardes, dos Santos Sanna, Paula Lemes, da Silva, Rodrigo A. Foganholi, Latini, Alexandra“…The negative modulation of the inflammatory response induced by caffeine involved the reduction of inflammasome components, Asc and Casp1, promoting an anti-inflammatory scenario. Caffeine treatment per se promoted the upregulation of adenosinergic receptors, Adora1 and Adora2A, an effect that was counterbalanced by LPS. …”
Publicado 2023
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1655“…Articles were shortlisted using Population, Intervention, Control, and Outcomes (PICO) search design and quality assessment was completed using Jadad, STROBE (Strengthening the Reporting of Observational studies in Epidemiology), Delphi, and Critical Appraisal Skills Program (CASP) followed by data extraction by two independent authors. …”
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1656“…The critical appraisal skills program (CASP) checklist was used to assess the articles' quality. …”
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1657por Su, Duntao, Zhang, Zeyu, Xia, Fada, Liang, Qiuju, Liu, Yuanhong, Liu, Wei, Xu, Zhijie“…Three ICD-related prognostic genes, the prion protein gene (PRNP), dynamin 1-like gene (DNM1L), and caspase-8 (CASP8), were identified and used to construct a risk signature. …”
Publicado 2023
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1658por Meng, Guangqiang, Li, Mingying, Xia, Yuan, Wu, Yuyan, Ma, Yuechan, Ji, Min, Zhang, Jingru, Ye, Jingjing, Sun, Tao, Ji, Chunyan“…METHODS: We utilized the CRISPR/Cas9 screening system to find AML anthracyclines resistance related genes and several mitochondrial apoptosis-related genes, such as BCL2L11, CASP8, TP63, TP53BP2, PLAUR, SOD2, BNIP3L, and MMP9, were screened out. …”
Publicado 2023
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1659por Grau-Del Valle, Carmen, Fernández, Javier, Solá, Eva, Montoya-Castilla, Inmaculada, Morillas, Carlos, Bañuls, Celia“…We included original studies in humans with a control group published in the last 11 years, which were assessed by the Critical Appraisal Skills Program (CASP) to confirm their quality. Eighteen articles met all the selection criteria. …”
Publicado 2023
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1660por Amir, Haeril, Permatananda, Pande Ayu Naya Kasih, Cahyani, Desy Dwi, Langelo, Wahyuny, Rosita, Rosita, Sajodin, Sajodin, Noprianty, Richa, Astuti, Anggia, Suhari, Suhari, Wahyuningsih, Sri, Kusumawati, Prima Dewi, Swamilaksita, Prita Dhyani, Sudarman, Sudarman, Syaiful, Syaiful“…The quality assessment of each article was performed using the Critical Appraisal Skills Program (CASP). During the initial database search, we retrieved 997 articles from Scopus, 700 articles from ProQuest, 357,554 articles from PubMed, and 1,526 articles from ScienceDirect. …”
Publicado 2023
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