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1661por Lazem, Hatem, Hall, Abi, Gomaa, Yasmine, Mansoubi, Maedeh, Lamb, Sallie, Dawes, Helen“…Methodological quality was assessed using the Cochrane Risk of Bias assessment tool for quantitative papers and the CASP scale for qualitative studies. All results are presented narratively. …”
Publicado 2023
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1662por Sevastidis, Abraham, Wanni Arachchige Dona, Sithara, Gold, Lisa, Sciberra, Emma, Coghill, David, Le, Ha Nguyet Dao“…Study quality was assessed using the Critical Appraisal Skills Program (CASP), Joanna Briggs Institute (JBI) and Mixed Methods Appraisal Tool (MMAT) checklists. …”
Publicado 2023
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1663por Rachwał, Kamila, Niedźwiedź, Iwona, Waśko, Adam, Laskowski, Tomasz, Szczeblewski, Paweł, Kukula-Koch, Wirginia, Polak-Berecka, Magdalena“…Additionally, mRNA expression analysis revealed significant upregulation of several genes, i.e., casp9, mapk10, mapk11, fas, kat2 b, and ubd, suggesting the induction of cell apoptosis through the caspase-dependent pathway. …”
Publicado 2023
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1664por Pinto, Vitor Batista, Vidigal, Pedro Marcus Pereira, Dal-Bianco, Maximiller, Almeida-Silva, Fabricio, Venancio, Thiago Motta, Viana, José Marcelo Soriano“…Important genes identified, such as HDT1, SWEET4a, GSTs, SAD9, PIP2-2, CASP-like 5, and AGP, may benefit molecular assisted popcorn breeding or be useful in biotechnological approaches. …”
Publicado 2023
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1665“…RESULTS: The proposed model achieved average prediction accuracy of 67% on the Benchmark_2 dataset for domain boundary identification in multi-domains proteins and showed superior predictive performance and generalisation ability among the most widely used neural network models. With the CASP7 benchmark dataset, it also demonstrated comparable performance to existing domain boundary predictors such as DOMpro, DomPred, DomSSEA, DomCut and DomainDiscovery with 70.10% prediction accuracy. …”
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1666“…Moreover, we compare DISpro with seven other automated disorder predictors on the 95 protein targets used in the seventh edition of Critical Assessment of Techniques for Protein Structure Prediction (CASP7). DISpro is ranked as one of the best predictors. …”
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1667“…In the seventh Critical Assessment of Structure Prediction (CASP7) experiment, the refined models produced are more accurate than the starting initial models. …”
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1668“…A comparison with other domain prediction methods used in the CASP7 competition indicates that our method performs better than existing sequence-based methods.…”
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1669por Quesada, Víctor, Velasco, Gloria, Puente, Xose S, Warren, Wesley C, López-Otín, Carlos“…Furthermore, we found several zebra finch-specific features, such as duplications in CASP3 and BACE, and a large genomic expansion of acrosin. …”
Publicado 2010
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1670“…CPHmodels-3.0 was benchmarked in the CASP8 competition and produced models for 94% of the targets (117 out of 128), 74% were predicted as high reliability models (87 out of 117). …”
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1671por Aljabri, M. B., Lund, T., Höper, A. C., Andreasen, T. V., Al-Saad, S., Lindal, S., Ytrehus, K.“…Ang II increased expression of genes related to heart function (ANF, β-MCH, Ankrd-1, PKC-α, PKC-δ TNF-α); fibrosis (Col I-α1, Col III-α1, Fn-1, Timp1) and apoptosis (P53, Casp-3) without changing heart weight but with 68% increase in collagen content. …”
Publicado 2010
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1672“…Furthermore, we demonstrate that NCACO-score can effectively guide fragment assembly for protein structure prediction, which has achieved a good performance in building the structure models for hard targets from CASP8 in terms of both accuracy and speed. CONCLUSIONS: Although NCACO-score is developed based on a coarse-grained model, it is able to discriminate native conformers from decoy conformers with high accuracy. …”
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1673por Barrett, Jennifer H, Iles, Mark M, Harland, Mark, Taylor, John C, Aitken, Joanne F, Andresen, Per Arne, Akslen, Lars A, Armstrong, Bruce K, Avril, Marie-Francoise, Azizi, Esther, Bakker, Bert, Bergman, Wilma, Bianchi-Scarrà, Giovanna, Paillerets, Brigitte Bressac-de, Calista, Donato, Cannon-Albright, Lisa A, Corda, Eve, Cust, Anne E, Dębniak, Tadeusz, Duffy, David, Dunning, Alison, Easton, Douglas F, Friedman, Eitan, Galan, Pilar, Ghiorzo, Paola, Giles, Graham G, Hansson, Johan, Hocevar, Marko, Höiom, Veronica, Hopper, John L, Ingvar, Christian, Janssen, Bart, Jenkins, Mark A, Jönsson, Göran, Kefford, Richard F, Landi, Giorgio, Landi, Maria Teresa, Lang, Julie, Lubiński, Jan, Mackie, Rona, Malvehy, Josep, Martin, Nicholas G, Molven, Anders, Montgomery, Grant W, van Nieuwpoort, Frans A, Novakovic, Srdjan, Olsson, Håkan, Pastorino, Lorenza, Puig, Susana, Puig-Butille, Joan Anton, Randerson-Moor, Juliette, Snowden, Helen, Tuominen, Rainer, Van Belle, Patricia, van der Stoep, Nienke, Whiteman, David C, Zelenika, Diana, Han, Jiali, Fang, Shenying, Lee, Jeffrey E, Wei, Qingyi, Lathrop, G Mark, Gillanders, Elizabeth M, Brown, Kevin M, Goldstein, Alisa M, Kanetsky, Peter A, Mann, Graham J, MacGregor, Stuart, Elder, David E, Amos, Christopher I, Hayward, Nicholas K, Gruis, Nelleke A, Demenais, Florence, Newton Bishop, Julia A, Bishop, D Timothy“…Three of the 7 regions replicated at p<10(−3): an ATM missense polymorphism (rs1801516, overall p=3.4×10(−9)); a polymorphism within MX2 (rs45430, p=2.9×10(−9)) and a SNP adjacent to CASP8 (rs13016963, p=8.6×10(−10)). A fourth region near CCND1 remains of potential interest, showing suggestive but inconclusive evidence of replication. …”
Publicado 2011
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1674“…Our assessment on a subset of proteins from the Critical Assessment of techniques for protein Structure Prediction (CASP) experiment has shown that BeEP is capable of discriminating the models and selecting one or more native-like structures. …”
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1675por Negoro, Hiromitsu, Lutz, Sarah E., Liou, Louis S., Kanematsu, Akihiro, Ogawa, Osamu, Scemes, Eliana, Suadicani, Sylvia O.“…IL-1β also increased IL-1β, IL-1R-1, PANX1 and CASP1 expression. Mefloquine (Panx1 blocker) reduced these IL-1β responses. …”
Publicado 2013
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1676por Wybranska, Iwona, Polus, Anna, Mikolajczyk, Magdalena, Knapp, Anna, Sliwa, Agnieszka, Zapala, Barbara, Staszel, Teresa, Dembinska-Kiec, Aldona“…A number of genes demonstrated statistically significant changes in their expressions, including BAX (BCL2-associated X protein); the CARD4/NLR family, CARD domain containing 4; CASP10 (caspase 10, apoptosis-related cysteine peptidase); DAP1 (death-associated protein kinase 1), and BIRC5 (baculoviral IAP repeat-containing 5). …”
Publicado 2013
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1677“…We searched the relevant databases, bibliography of related papers, and laws, using appropriate search strategies and key words. The CASP tool was used by two experts to evaluate the quality of retrieved papers and inconsistencies were resolved by discussion. …”
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1678Publicado 2015“…A subgroup of oral cavity tumours with favourable clinical outcomes displayed infrequent copy number alterations in conjunction with activating mutations of HRAS or PIK3CA, coupled with inactivating mutations of CASP8, NOTCH1 and TP53. Other distinct subgroups contained loss-of-function alterations of the chromatin modifier NSD1, WNT pathway genes AJUBA and FAT1, and activation of oxidative stress factor NFE2L2, mainly in laryngeal tumours. …”
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1679por Ilagan, Janine O., Ramakrishnan, Aravind, Hayes, Brian, Murphy, Michele E., Zebari, Ahmad S., Bradley, Philip, Bradley, Robert K.“…U2AF1 mutations cause differential splicing of hundreds of genes, affecting biological pathways such as DNA methylation (DNMT3B), X chromosome inactivation (H2AFY), the DNA damage response (ATR, FANCA), and apoptosis (CASP8). We show that U2AF1 mutations alter the preferred 3′ splice site motif in patients, in cell culture, and in vitro. …”
Publicado 2015
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1680“…Results: We describe DISOPRED3, which extends its predecessor with new modules to predict IDRs and protein-binding sites within them. Based on recent CASP evaluation results, DISOPRED3 can be regarded as state of the art in the identification of IDRs, and our self-assessment shows that it significantly improves over DISOPRED2 because its predictions are more specific across the whole board and more sensitive to IDRs longer than 20 amino acids. …”
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