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1701“…The ModFOLD6 methods rank among the top few for EMA, according to independent blind testing by the CASP12 assessors. The ModFOLD6 server is also continuously automatically evaluated as part of the CAMEO project, where significant performance gains have been observed compared to our previous server and other publicly available servers. …”
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1702por Berta, Temugin, Perrin, Florence E., Pertin, Marie, Tonello, Raquel, Liu, Yen-Chin, Chamessian, Alexander, Kato, Ann C., Ji, Ru-Rong, Decosterd, Isabelle“…We validated the increase of caspase-6 (CASP6) in small-sized DRG neurons and its functional role in SNI- and paclitaxel-induced neuropathic pain. …”
Publicado 2017
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1703“…We found that panbinostat and the combination increased levels of mRNAs encoding TNF/TNFR family members, as well as BNIP3L and CASP-9, and markedly decreased mRNA levels for c-FLIP and BID. …”
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1704“…We also evaluate the performance on the CASP11 benchmark dataset, DeepSacon achieves 0.68 three-state accuracy and 0.69 PCC for solvent accessibility and contact number, respectively. …”
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1705“…Quality assessment of this study was executed by using the Critical Appraisal Skills Programme (CASP). All of these studies were selected for meta-analysis by Comprehensive meta-analysis version 2.0. …”
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1706“…Our results indicated that CKI exerted anti-HCC effects via the key targets MMP2, MYC, CASP3, and REG1A and the key pathways of glycometabolism and amino acid metabolism. …”
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1707“…Whereas TNF-α has an inducible expression, IL-18 is translated as an inactive protein and required proteolytic cleavage by Casp-1 in inflammasome complexes. AIM: To investigate the effect of the histone deacetylases inhibitor Suberoylanilide Hydroxamic Acid (SAHA) on the gene expression and secretion of both cytokines, IL-18 and TNF-α, according to their contribution to the cancer development and anticancer immunity. …”
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1708por Albano, Francesco, Chiurazzi, Federico, Mimmi, Selena, Vecchio, Eleonora, Pastore, Arianna, Cimmino, Clementina, Frieri, Camilla, Iaccino, Enrico, Pisano, Antonio, Golino, Gaetanina, Fiume, Giuseppe, Mallardo, Massimo, Scala, Giuseppe, Quinto, Ileana“…Consistently, RNA interference of IBTKα up regulated the expression of pro-apoptotic genes, including TNF, CRADD, CASP7, BNIP3 and BIRC3. Our results indicate that IBTKα is a novel marker of CLL progression promoting cell growth and resistance to apoptosis. …”
Publicado 2018
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1709por Krupa, Petr, Vackova, Irena, Ruzicka, Jiri, Zaviskova, Kristyna, Dubisova, Jana, Koci, Zuzana, Turnovcova, Karolina, Machova Urdzikova, Lucia, Kubinova, Sarka, Rehak, Svatopluk, Jendelova, Pavla“…Endogenous gene expression (Gfap, Casp3, Irf5, Cd86, Mrc1, Cd163) was studied with quantitative Real-time polymerase chain reaction (qRT PCR). …”
Publicado 2018
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1710por Serou, N., Sahota, L., Husband, A. K., Forrest, S. P., Moorthy, K., Vincent, C., Slight, R. D., Slight, S. P.“…A data extraction form was used to capture pertinent information from included studies and the Critical Appraisal Skills Programme (CASP) tool to appraise their quality. PRISMA‐P reporting guidelines were followed and the review is registered with PROSPERO. …”
Publicado 2017
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1711“…The initial results included 2795 papers, but after further investigation and qualitative evaluation using CASP-19, a total of 8 papers were included in the systematic review. …”
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1712por Kopp, Sascha, Krüger, Marcus, Feldmann, Stefan, Oltmann, Hergen, Schütte, Andreas, Schmitz, Burkhard, Bauer, Johann, Schulz, Herbert, Saar, Kathrin, Huebner, Norbert, Wehland, Markus, Nassef, Mohamed Zakaria, Melnik, Daniela, Meltendorf, Stefan, Infanger, Manfred, Grimm, Daniela“…EGF upregulates aspartate beta-hydroxylase (ASPH) which is influencing CASP3. Hyper-g induced a significant up-regulation of TUBB1, VIM, RDX, CAV1, VEGFA and BCL2. …”
Publicado 2018
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1713por Hosonaga, Mari, Arima, Yoshimi, Sampetrean, Oltea, Komura, Daisuke, Koya, Ikuko, Sasaki, Takashi, Sato, Eiichi, Okano, Hideyuki, Kudoh, Jun, Ishikawa, Shumpei, Saya, Hideyuki, Ishikawa, Takashi“…RNA sequence analysis showed that CASP-1 and its related genes were significantly downregulated in metastatic brain tumors with HER2-60 cells. …”
Publicado 2018
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1714“…The risk of bias in the included articles was assessed using the Cochrane Collaboration’s tool for assessing risk of bias for randomised controlled trials (RCTs), RoBANS for non-RCT studies, and CASP for qualitative studies. RESULTS: For the systematic review, 45 out of 14,994 articles were analysed. …”
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1715por Martin, Judith M, Avula, Raghunandan, Nowalk, Mary Patricia, Lin, Chyongchiou Jeng, Horne, William T, Chandran, Uma R, Nagg, Jennifer P, Zimmerman, Richard K, Cole, Kelly S, Alcorn, John F“…For LAIV, CART showed that changes in expression of CD80, CXCL2, and CASP1 were associated with seroprotection. Serum cytokines showed that IIV seroconversion was associated with decreased CCL3. …”
Publicado 2018
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1716por Zhuge, Ying, Ni, Huan-Er, Wang, Yu-Jie, He, Mu-Ye, Wang, Jun-Shan, Gao, Feng, Wang, Fang“…Fluorescence spectrophotometry was used to assess reagent bio-distribution, while Western blots and immunohistochemistry were used to assess the localization of the apoptotic markers Bcl-2, Bax, and cleaved CASP3 in the LAA. Liver, kidney, and cardiac functions were also measured to evaluate the safety of this approach. …”
Publicado 2018
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1717por Chen, Ruochan, Zeng, Ling, Zhu, Shan, Liu, Jiao, Zeh, Herbert J., Kroemer, Guido, Wang, Haichao, Billiar, Timothy R., Jiang, Jianxin, Tang, Daolin, Kang, Rui“…Consequently, pharmacological modulation of the ADRA2B-ADCY4-PDE8A-PKA axis, knockout of caspase-11 (Casp11(−/−)), or Gsdmd inactivation (Gsdmd(I105N/I105N)) similarly protects against LPS-induced lethality in poly(I:C)-primed mice. …”
Publicado 2019
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1718por Sarkar, Sutapa, Kimono, Diana, Albadrani, Muayad, Seth, Ratanesh K., Busbee, Philip, Alghetaa, Hasan, Porter, Dwayne E., Scott, Geoff I., Brooks, Bryan, Nagarkatti, Mitzi, Nagarkatti, Prakash, Chatterjee, Saurabh“…Activationof NOX2 caused inflammasome activation as shown by NLRP3/ASCII and NLRP3/Casp-1 colocalizations in these cells while use of mice lacking a crucial NOX2 component attenuated inflammatory pathology and redox changes. …”
Publicado 2019
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1719por Vidmar, Lovro, Maver, Ales, Drulović, Jelena, Sepčić, Juraj, Novaković, Ivana, Ristič, Smiljana, Šega, Saša, Peterlin, Borut“…These variants were found in inflammasome genes (NLRP1/3, CASP1), genes mediating inflammasome inactivation via auto and mitophagy (RIPK2, MEFV), and genes involved in response to infection with DNA viruses (POLR3A, DHX58, IFIH1) and to type-1 interferons (TYK2, PTPRC). …”
Publicado 2019
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1720por McGuffin, Liam J, Adiyaman, Recep, Maghrabi, Ali H A, Shuid, Ahmad N, Brackenridge, Danielle A, Nealon, John O, Philomina, Limcy S“…The component methods have been independently evaluated via the successive blind CASP experiments and the continual CAMEO benchmarking project. …”
Publicado 2019
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