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  1. 1201
    “…METHODS AND FINDINGS: We conducted a multicenter two-arm, cluster randomized controlled trial in 3 health districts in Spain (primary health centers [PHCs] in Balearic Islands, Catalonia, and Valencian Community) from September 2016 to May 2018. …”
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    Evaluation of a multicomponent intervention consisting of education and feedback to reduce benzodiazepine prescriptions by general practitioners: The BENZORED hybrid type 1 cluster randomized controlled trial
  2. 1202
    “…A cRCT will be conducted in 24 PC teams in Catalonia (Spain), randomly assigned to the intervention group (1:1), and community pharmacies in the catchment areas of the intervention PC teams. …”
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    Effectiveness and cost-effectiveness of an intervention to improve Initial Medication Adherence to treatments for cardiovascular diseases and diabetes in primary care: study protocol for a pragmatic cluster randomised controlled trial and economic model (the IMA-cRCT study)
  3. 1203
    “…CMBD-HA is a mandatory population-based register of admissions to all public and private acute-care hospitals in Catalonia. Sepsis was defined by the presence of infection and at least one organ dysfunction. …”
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    Trends in mortality in septic patients according to the different organ failure during 15 years
  4. 1204
    “…The aim of our study is to analyse the trends in the incidence of 7 commonly managed primary care chronic diseases during the last 2 years of the COVID-19 pandemic in Catalonia. METHODS: We performed an observational retrospective population-based study using data from primary care electronic health records from January 2018 to August 2022 (5.1 million people older than 14 years). …”
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    “Decline and uneven recovery from 7 common long-term conditions managed in the Catalan primary care after two pandemic years: an observational retrospective population-based study using primary care electronic health records”
  5. 1205
    “…METHODS: Cross-sectional analysis of the baseline of the ongoing VIMCI (Validity of an Instrument to Measure Intrinsic Capacity) cohort study, which was carried out in Primary Care centers and outpatient clinics from 5 rural and urban territories in Catalonia (Spain). Participants were 207community dwelling persons ≥ 70-year-old with Barthel [Formula: see text] 90, without dementia or advanced chronic conditions who provided their consent to participate. …”
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    Identification of decreased intrinsic capacity: Performance of diagnostic measures of the ICOPE Screening tool in community dwelling older people in the VIMCI study
  6. 1206
    “…METHODS: Population-based cohort study involving 2,059,645 persons ≥ 50 years-old in Catalonia, Spain, who were retrospectively followed between 01/01/2017-31/12/2018. …”
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    Incidence and risk factors of pneumococcal pneumonia in adults: a population-based study
  7. 1207
    “…A real-word, evidence-based retrospective cohort study was conducted at Vall d’Hebron University Hospital (VHUH), the largest hospital complex in Catalonia, Spain, in order to determine the use of drugs and the associated cost in real clinical practice for the treatment of solid tumors in adult patients attended at this institution over 10 years (2010–2019). …”
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    Use of Drugs in Clinical Practice and the Associated Cost of Cancer Treatment in Adult Patients with Solid Tumors: A 10-Year Retrospective Cohort Study
  8. 1208
    “…METHODS: A cross-sectional study was carried out in eight primary care centres (PCCs) in four non-randomly selected health regions of Catalonia, Spain from March to December 2018. Routine health data and mental health diagnoses based on the International Classification of Diseases (10th edition), including mental, behavioural and neuro developmental disorders (F01-F99), symptoms and signs involving emotional state (R45), and sleep disorders (G47), were extracted from the electronic health records. …”
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    Screening and routine diagnosis of mental disorders among migrants in primary care: A cross-sectional study
  9. 1209
    “…Data were obtained from two European countries, Spain and Sweden, and from three centers: Consorci Sanitari de Terrassa (Catalonia, Spain), Servicio Andaluz de Salud (Andalusia, Spain), and the Blekinge Institute of Technology (Sweden). …”
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    Attitudes and Use of Information and Communication Technologies in Older Adults With Mild Cognitive Impairment or Early Stages of Dementia and Their Caregivers: Cross-Sectional Study
  10. 1210
    “…METHODS: As part of the CONNECARE Horizon 2020 project, a prospective, pragmatic, 2-arm, parallel, hybrid effectiveness-implementation trial was conducted from July 2018 to August 2019 in a rural region of Catalonia, Spain. Home-dwelling patients 55 years and older with chronic conditions and a history of hospitalizations for chronic obstructive pulmonary disease or heart failure (use case [UC] 1), or a scheduled major elective hip or knee arthroplasty (UC2) were recruited. …”
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    Implementing Mobile Health–Enabled Integrated Care for Complex Chronic Patients: Patients and Professionals’ Acceptability Study
  11. 1211
    “…METHODS AND FINDINGS: We followed up a population-based sample of 2,680 children aged 7 to 10 years from 38 schools in Barcelona (Catalonia, Spain) between January 2012 to March 2013. …”
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    Exposure to road traffic noise and cognitive development in schoolchildren in Barcelona, Spain: A population-based cohort study
  12. 1212
    “…We identified six sCJD cases, 4 in Catalonia and 2 in Italy, carrying MV at PRNP codon 129 in combination with PrP(Sc) type 1 and a new clinical and neuropathological profile reminiscent of the VV1 sCJD subtype rather than typical MM1/MV1. …”
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    Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease
  13. 1213
    “…DESIGN, SETTING, AND PARTICIPANTS: This cohort study included 1.1 million children and adolescents (aged 2-17 years) with at least 1 measure of height and weight in Catalonia, Spain, from 2006 to 2016. Electronic health records were accessed from the Information System for Research in Primary Care. …”
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    Time Trends and Sociodemographic Factors Associated With Overweight and Obesity in Children and Adolescents in Spain
  14. 1214
    “…Objective To determine whether the effectiveness (major thromboembolic events) and safety (bleedings) of edoxaban or low molecular weight heparin (LMWH) were different among patients with AF that had been hospitalized for COVID-19 infection in Catalonia, Spain. Methods Observational and multicenter study with a retrospective analysis that consecutively included from March 5th to April 27st 2020 hospitalized patients with the diagnosis of non-valvular AF who received anticoagulant treatment with LMWH or edoxaban concomitantly with the empirical therapy used for COVID-19 infection. …”
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    Edoxaban Vs. Low Molecular Weight Heparin As Anticoagulant Therapy in Hospitalized Patients with Atrial Fibrillation and COVID-19 Infection
  15. 1215
    por Houwaart, Torsten, Belhaj, Samir, Tawalbeh, Emran, Nagels, Dirk, Fröhlich, Yara, Finzer, Patrick, Ciruela, Pilar, Sabrià, Aurora, Herrero, Mercè, Andrés, Cristina, Antón, Andrés, Benmoumene, Assia, Asskali, Dounia, Haidar, Hussein, von Dahlen, Janina, Nicolai, Jessica, Stiller, Mygg, Blum, Jacqueline, Lange, Christian, Adelmann, Carla, Schroer, Britta, Osmers, Ute, Grice, Christiane, Kirfel, Phillipp P., Jomaa, Hassan, Strelow, Daniel, Hülse, Lisanna, Pigulla, Moritz, Kreuzer, Pascal, Tyshaieva, Alona, Weber, Jonas, Wienemann, Tobias, Kohns Vasconcelos, Malte, Hoffmann, Katrin, Lübke, Nadine, Hauka, Sandra, Andree, Marcel, Scholz, Claus Jürgen, Jazmati, Nathalie, Göbels, Klaus, Zotz, Rainer, Pfeffer, Klaus, Timm, Jörg, Ehlkes, Lutz, Walker, Andreas, Dilthey, Alexander T., Altmüller, Janine, Angelov, Angel, Aschenbrenner, Anna C., Bals, Robert, Bartholomäus, Alexander, Becker, Anke, Becker, Matthias, Bezdan, Daniela, Bitzer, Michael, Blumert, Conny, Bonifacio, Ezio, Bork, Peer, Boyke, Bunk, Blum, Helmut, Casadei, Nicolas, Clavel, Thomas, Colome-Tatche, Maria, Cornberg, Markus, De La Rosa Velázquez, Inti Alberto, Diefenbach, Andreas, Dilthey, Alexander, Fischer, Nicole, Förstner, Konrad, Franzenburg, Sören, Frick, Julia-Stefanie, Gabernet, Gisela, Gagneur, Julien, Ganzenmueller, Tina, Gauder, Marie, Geißert, Janina, Goesmann, Alexander, Göpel, Siri, Grundhoff, Adam, Grundmann, Hajo, Hain, Torsten, Hanses, Frank, Hehr, Ute, Heimbach, André, Hoeper, Marius, Horn, Friedemann, Hübschmann, Daniel, Hummel, Michael, Iftner, Thomas, Iftner, Angelika, Illig, Thomas, Janssen, Stefan, Kalinowski, Jörn, Kallies, René, Kehr, Birte, Keller, Andreas, Keppler, Oliver T., Kim-Hellmuth, Sarah, Klein, Christoph, Knop, Michael, Kohlbacher, Oliver, Köhrer, Karl, Korbel, Jan, Kremsner, Peter G., Kühnert, Denise, Kurth, Ingo, Landthaler, Markus, Li, Yang, Ludwig, Kerstin U., Makarewicz, Oliwia, Marz, Manja, McHardy, Alice C., Mertes, Christian, Münchhoff, Maximilian, Nahnsen, Sven, Nöthen, Markus, Ntoumi, Francine, Nürnberg, Peter, Ossowski, Stephan, Overmann, Jörg, Peter, Silke, Pfeffer, Klaus, Pink, Isabell, Poetsch, Anna R., Protzer, Ulrike, Pühler, Alfred, Rajewsky, Nikolaus, Ralser, Markus, Reiche, Kristin, Rieß, Olaf, Ripke, Stephan, Nunes da Rocha, Ulisses, Rosenstiel, Philip, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Sawitzki, Birgit, Scheithauer, Simone, Schiffer, Philipp, Schmid-Burgk, Jonathan, Schneider, Wulf, Schulte, Eva-Christina, Schultze, Joachim L., Sczyrba, Alexander, Sharaf, Mariam L., Singh, Yogesh, Sonnabend, Michael, Stegle, Oliver, Stoye, Jens, Theis, Fabian, Ulas, Thomas, Vehreschild, Janne, Velavan, Thirumalaisamy P., Vogel, Jörg, Volland, Sonja, von Kleist, Max, Walker, Andreas, Walter, Jörn, Wieczorek, Dagmar, Winkler, Sylke, Ziebuhr, John
    Publicado 2022
    “…Supported by viral genome data from Spain, Cluster 2 was shown to represent multiple independent introduction events of a viral strain circulating in Catalonia and other European countries, followed by diffuse community transmission in Düsseldorf. …”
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    Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021
  16. 1216
    por Bancroft, Elizabeth K, Page, Elizabeth C, Brook, Mark N, Thomas, Sarah, Taylor, Natalie, Pope, Jennifer, McHugh, Jana, Jones, Ann-Britt, Karlsson, Questa, Merson, Susan, Ong, Kai Ren, Hoffman, Jonathan, Huber, Camilla, Maehle, Lovise, Grindedal, Eli Marie, Stormorken, Astrid, Evans, D Gareth, Rothwell, Jeanette, Lalloo, Fiona, Brady, Angela F, Bartlett, Marion, Snape, Katie, Hanson, Helen, James, Paul, McKinley, Joanne, Mascarenhas, Lyon, Syngal, Sapna, Ukaegbu, Chinedu, Side, Lucy, Thomas, Tessy, Barwell, Julian, Teixeira, Manuel R, Izatt, Louise, Suri, Mohnish, Macrae, Finlay A, Poplawski, Nicola, Chen-Shtoyerman, Rakefet, Ahmed, Munaza, Musgrave, Hannah, Nicolai, Nicola, Greenhalgh, Lynn, Brewer, Carole, Pachter, Nicholas, Spigelman, Allan D, Azzabi, Ashraf, Helfand, Brian T, Halliday, Dorothy, Buys, Saundra, Ramon y Cajal, Teresa, Donaldson, Alan, Cooney, Kathleen A, Harris, Marion, McGrath, John, Davidson, Rosemarie, Taylor, Amy, Cooke, Peter, Myhill, Kathryn, Hogben, Matthew, Aaronson, Neil K, Ardern-Jones, Audrey, Bangma, Chris H, Castro, Elena, Dearnaley, David, Dias, Alexander, Dudderidge, Tim, Eccles, Diana M, Green, Kate, Eyfjord, Jorunn, Falconer, Alison, Foster, Christopher S, Gronberg, Henrik, Hamdy, Freddie C, Johannsson, Oskar, Khoo, Vincent, Lilja, Hans, Lindeman, Geoffrey J, Lubinski, Jan, Axcrona, Karol, Mikropoulos, Christos, Mitra, Anita V, Moynihan, Clare, Ni Raghallaigh, Holly, Rennert, Gad, Collier, Rebecca, Offman, Judith, Kote-Jarai, Zsofia, Eeles, Rosalind A
    Publicado 2021
    “…FUNDING: Cancer Research UK, The Ronald and Rita McAulay Foundation, the National Institute for Health Research support to Biomedical Research Centres (The Institute of Cancer Research and Royal Marsden NHS Foundation Trust; Oxford; Manchester and the Cambridge Clinical Research Centre), Mr and Mrs Jack Baker, the Cancer Council of Tasmania, Cancer Australia, Prostate Cancer Foundation of Australia, Cancer Council of Victoria, Cancer Council of South Australia, the Victorian Cancer Agency, Cancer Australia, Prostate Cancer Foundation of Australia, Asociación Española Contra el Cáncer (AECC), the Instituto de Salud Carlos III, Fondo Europeo de Desarrollo Regional (FEDER), the Institut Català de la Salut, Autonomous Government of Catalonia, Fundação para a Ciência e a Tecnologia, National Institutes of Health National Cancer Institute, Swedish Cancer Society, General Hospital in Malmö Foundation for Combating Cancer.…”
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    A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study
  17. 1217
    “…PARTICIPANTS: The study will be performed at the Institut Català d’Oncologia, a tertiary level oncological referral center in the Catalonia region (Spain). The eligibility criteria are: patients > 18 years affected by oncological diseases; ECOG performance status < 2 (Karnofsky score > 60%); a laboratory confirmed infection with SARS-CoV-2 by means of real -time PCR; radiological signs of low respiratory tract disease; absence of organ dysfunction (a total bilirubin within normal institutional limits, AST/ALT≤2.5 X institutional upper limit of normal, alkaline phosphatase ≤2.5 X institutional upper limit of normal, coagulation within normal institutional limits, creatinine clearance >30 mL/min/1.73 m(2) for patients with creatinine levels above institutional normal); absence of HIV infection; no active or latent HBV or HCV infection. …”
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    A Phase I/II Clinical Trial to evaluate the efficacy of baricitinib to prevent respiratory insufficiency progression in onco-hematological patients affected with COVID19: A structured summary of a study protocol for a randomised controlled trial
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