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  1. 228721
    “…62Articular cartilage is a nonvascularized and poorly cellularized tissue with a low self-repair capacity. …”
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    3D bioprinting of ultrashort self-assembling peptides to engineer scaffolds with different matrix stiffness for chondrogenesis
  2. 228722
    “…Many gene editing efforts to treat the β-hemoglobinopathies attempt to correct β-globin mutations or increase γ-globin for fetal hemoglobin production. δ-globin, the subunit of adult hemoglobin A2, has high homology to β-globin and is already pan-cellularly expressed at low levels in adult red blood cells. …”
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    Engineering of the endogenous HBD promoter increases HbA2
  3. 228723
    “…The drug also increased bone marrow cellularity and megakaryocytes, accelerated multi-lineage hematopoietic recovery, and alleviated radiation-induced soluble markers of bone marrow aplasia and endothelial damage. …”
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    PEGylated thrombopoietin mimetic, JNJ‑26366821 a novel prophylactic radiation countermeasure for acute radiation injury
  4. 228724
    “…RESULTS: At 60 days, compared to normal controls, SARS patients had increased cellularity of BALF with increased alveolar macrophages (AM) and CD8 cells. …”
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    Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS
  5. 228725
    “…The prevention of cell death by loss of p53 restored numbers of early T cell progenitors but did not fully restore thymic cellularity. Further analysis revealed that loss of Rho function caused survival defects in CD4/8 double-positive thymocytes that is independent of p53 but can be prevented by ectopic expression of Bcl-2. …”
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    The Gtpase Rho Controls a P53-Dependent Survival Checkpoint during Thymopoiesis
  6. 228726
    “…The syngeneic plasmacytoma NS-1 was used as target in a 4th in vitro NK-cell microassay. Marrow cellularity in treated mice is reduced to 12.5% of controls, but haemopoietic and stem-cell functions are taken over by the spleen and the peripheral blood picture remains relatively normal. …”
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    Mice treated with strontium 90: an animal model deficient in NK cells.
  7. 228727
    Publicado 1993
    “…At death, SCID mice that received the CD4+/CD45RBhi cells had increased spleen and lymph node cellularity compared with normal SCID mice and SCID mice that received the CD4+/CD45RBlo T cells. …”
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    CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells
  8. 228728
    “…In older p55(−/−) mice (>6 mo), we identified significant differences in their hematopoietic system compared with age-matched p75(−/−) or wild-type counterparts. Increased marrow cellularity and increased numbers of myeloid and erythroid colony-forming progenitor cells (CFCs), paralleled by elevated peripheral blood cell counts, were found in p55-deficient mice. …”
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    Essential Role for the P55 Tumor Necrosis Factor Receptor in Regulating Hematopoiesis at a Stem Cell Level
  9. 228729
    “…After infection of IRF4(−/−) mice with the protozoan parasite Leishmania major, the lesion-draining lymph nodes developed the prototypic lymphadenopathy of wild-type mice after 4 wk, but demonstrated almost total loss of cellularity and enhanced apoptosis after 7 wk. In vitro, activation of IRF4(−/−) CD4(+) Th cells led to greatly increased apoptosis compared with wild-type cells. …”
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    Enhanced TCR-induced Apoptosis in Interferon Regulatory Factor 4–deficient CD4(+) Th Cells
  10. 228730
    “…Plasma and hormone metabolites were determined together with variations in cellularity of adipose tissue. RESULTS: Treatment decreased food intake and lowered weight gain during late pregnancy, mainly because of reduced adipose tissue accumulation in different sites. …”
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    Treatment of pregnant rats with oleoyl-estrone slows down pup fat deposition after weaning
  11. 228731
    “…This hypertrophy is associated with increased absolute numbers of all thymocyte types, and with increased cortical and medullary cellularity. In the thymic medulla, increased compartmentalization of the major thymic stromal cell types and expansion of thymic epithelial cell population is observed. …”
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    Expression of the HPV16E7 Oncoprotein by Thymic Epithelium is Accompanied by Disrupted T Cell Maturation and a Failure of the Thymus to Involute with Age
  12. 228732
    “…Using mice expressing p110δ(D910A), a catalytically inactive p110δ, we show that these mice had reduced NK cellularity, defective Ly49C and Ly49I NK subset maturation, and decreased CD27(High) NK numbers. p110δ inactivation marginally impaired NK-mediated cytotoxicity against tumor cells in vitro and in vivo. …”
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    The p110δ of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation
  13. 228733
    “…METHODS: Crypt length, crypt cellularity and crypt cell proliferation were assessed in biopsies acquired after preparation with either Klean-Prep or Picolax. …”
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    Commonly used bowel preparations have significant and different effects upon cell proliferation in the colon: a pilot study
  14. 228734
    “…Here we present a detailed timeline of late meiotic prophase during spermatogenesis in Caenorhabditis elegans using cytological and molecular landmarks to interrelate changes in chromosome dynamics with germ cell cellularization, spindle formation, and cell cycle transitions. …”
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    Spermatogenesis-Specific Features of the Meiotic Program in Caenorhabditis elegans
  15. 228735
    “…In addition, AUF1-deficient mice exhibit a sharp decrease in splenic size and lymphocyte cellularity. Bone marrow transfer studies demonstrate that AUF1 deficiency induces cell-autonomous defects in mature B cell subsets but not in the overall number of splenocytes. …”
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    AUF1 is involved in splenic follicular B cell maintenance
  16. 228736
    “…Glioma progression is associated with elevated growth factor signaling and loss of function of tumor suppressors Ink4a, Arf and Pten. Yet, gliomas are cellularly heterogeneous; they recruit and trap normal cells during infiltration. …”
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    Recruited Cells Can Become Transformed and Overtake PDGF-Induced Murine Gliomas In Vivo during Tumor Progression
  17. 228737
    “…RESULTS: Out of 65 smears, 17 (26%) were discarded because of poor cellularity. A total of 28 of 29 (97%) smears with a histological proven (pre)malignancy had a smear classified as ‘suspicious’ or ‘uncertain’. …”
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    Cytology of the vulva: feasibility and preliminary results of a new brush
  18. 228738
    “…TP slides were satisfactory for evaluation in 31 (89%) cases, and less than optimal in four due to low cellularity, obscuring blood or air drying artifact. …”
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    Testicular touch preparation cytology in the evaluation of male infertility
  19. 228739
    “…We describe a procedure for extracting a usable concentration of total genomic DNA from cytogenetic suspensions of low cellularity. CONCLUSIONS: The ability to use these archival specimens for DNA-based analysis increases the potential for retrospective genetic analysis of clinical specimens. …”
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    CGH and SNP array using DNA extracted from fixed cytogenetic preparations and long-term refrigerated bone marrow specimens
  20. 228740
    “…Patients were defined as predicted PMs if: (1) they failed a previous collection attempt (not otherwise specified); (2) they previously received extensive radiotherapy or full courses of therapy affecting SC mobilization; and (3) they met two of the following criteria: advanced disease (⩾2 lines of chemotherapy), refractory disease, extensive BM involvement or cellularity <30% at the time of mobilization; age ⩾65 years. …”
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    Proposed definition of ‘poor mobilizer' in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo
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