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Inmunidad celular
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229521“…A first FNA performed was an uncomplicated biopsy of the lesion, but demonstrated insufficient cellularity on pathology. A second FNA performed was also an uncomplicated biopsy of the lesion, and demonstrated squamous cells, debris material suggestive of vegetable material, and rare benign follicular epithelial cells. …”
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229522por Tan, Mingjun, Mosaoa, Rami, Graham, Garrett T., Kasprzyk-Pawelec, Anna, Gadre, Shreyas, Parasido, Erika, Catalina-Rodriguez, Olga, Foley, Patricia, Giaccone, Giuseppe, Cheema, Amrita, Kallakury, Bhaskar, Albanese, Chris, Yi, Chunling, Avantaggiati, Maria LauraEnlace del recurso
Publicado 2020
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229523por Rytelewski, Mateusz, Harutyunyan, Karine, Baran, Natalia, Mallampati, Saradhi, Zal, M. Anna, Cavazos, Antonio, Butler, Jason M., Konoplev, Sergej, El Khatib, Mirna, Plunkett, Shane, Marszalek, Joseph R., Andreeff, Michael, Zal, Tomasz, Konopleva, Marina“…This intermediate stage was followed by a significant decrease of extracellular pO(2) and further increase of intracellular hypoxia as leukemia cellularity overwhelmed BM in disease end-stage. Remarkably, treatment of leukemic mice with IACS-010759, a pharmacological inhibitor of mitochondrial Complex I, substantially increased pO(2) in the BM with advanced B-ALL, and it alleviated intracellular hypoxia reported by pimonidazole staining. …”
Publicado 2020
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229524Publicado 2015“…RESULTS: Before TBI, WBC and LYM decreased in rapamycin-treated mice compared with control (P<0.01); RBC and HGB increased (P<0.05); there was no difference in PLT; HE staining of bone marrow from rapamcintreated and control mice before irradiation showed no difference in marrow cellularity. After TBI, WBC and LYM decreased significantly, with no difference at 0.5 d to 7 d between rapamycin-treated and control. …”
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229525
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229526por Vetma, Vesna, Guttà, Cristiano, Peters, Nathalie, Praetorius, Christian, Hutt, Meike, Seifert, Oliver, Meier, Friedegund, Kontermann, Roland, Kulms, Dagmar, Rehm, MarkusEnlace del recurso
Publicado 2020
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229527por Yi, Sang Ah, Lee, Dong Hoon, Kim, Go Woon, Ryu, Hyun-Wook, Park, Jong Woo, Lee, Jaecheol, Han, Jihoon, Park, Jee Hun, Oh, Hwamok, Lee, Jieun, Choi, Junjeong, Kim, Hyun-Soo, Kang, Hyeok Gu, Kim, Da-Hyun, Chun, Kyung-Hee, You, Jueng Soo, Han, Jeung-Whan, Kwon, So HeeEnlace del recurso
Publicado 2020
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229528por Sørensen, Anders Lindholm, Mikkelsen, Stine Ulrik, Knudsen, Trine Alma, Bjørn, Mads Emil, Andersen, Christen Lykkegaard, Bjerrum, Ole Weis, Brochmann, Nana, Patel, Dustin Andersen, Gjerdrum, Lise Mette Rahbek, El Fassi, Daniel, Kruse, Torben A., Larsen, Thomas Stauffer, Mourits-Andersen, Hans Torben, Nielsen, Claus Henrik, Ellervik, Christina, Pallisgaard, Niels, Thomassen, Mads, Kjær, Lasse, Skov, Vibe, Hasselbalch, Hans Carl“…In conclusion, combination treatment improved cell counts, reduced bone marrow cellularity and fibrosis, decreased JAK2 V617F burden, and reduced symptom burden with acceptable toxicity in several patients with polycythemia vera or myelofibrosis. …”
Publicado 2020
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229529por Malapelle, Umberto, Parente, Paola, Pepe, Francesco, De Luca, Caterina, Cerino, Pellegrino, Covelli, Claudia, Balestrieri, Mariangela, Russo, Gianluca, Bonfitto, Antonio, Pisapia, Pasquale, Fiordelisi, Fabiola, D’Armiento, Maria, Bruzzese, Dario, Loupakis, Fotios, Pietrantonio, Filippo, Triassi, Maria, Fassan, Matteo, Troncone, Giancarlo, Graziano, Paolo“…We selected the mucinous colorectal cancer (CRC) histotype for this study as it may possibly represent an intrinsic diagnostic issue due to its low tumor cellularity. Seventy-five cases of mucinous CRC and corresponding normal colon tissue samples were retrospectively selected. …”
Publicado 2020
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229530“…Therefore, a new rapid method of recellularizing these constructs to ensure high cellularity throughout the collagen scaffold is needed. …”
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229531Publicado 2020“…In patients with pre- and overt PMF, patients with JAK2V617F had increased cellularity(P=0.037). CALR-mutated patients had increased dense clusters and giant sizes of megakaryocytes, collagen, and osteosclerosis(P=0.055, P=0.059, P=0.011, P=0.046). …”
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229532por Bianchi, Giuseppe, Lana, Debora, Gambarotti, Marco, Ferrari, Cristina, Sbaraglia, Marta, Pedrini, Elena, Pazzaglia, Laura, Sangiorgi, Luca, Bartolotti, Isabella, Dei Tos, Angelo Paolo, Scotlandi, Katia, Righi, Alberto“…Morphologically, 15 cases evidenced high cellularity, cytologic atypia, and foci of necrosis and were associated with more than 4 mitotic figures/10 HPF. …”
Publicado 2021
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229533por Keshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M., Hume, David A.“…WT BM transfer restored osteoclasts, eliminated osteopetrosis, restored bone marrow cellularity and architecture and reversed granulocytosis and B cell deficiency. …”
Publicado 2021
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229534por Li, Xiaomei, Yuan, Jiahui, Song, Conghua, Lei, Yongbin, Xu, Jiajia, Zhang, Gongye, Wang, Weiwei, Song, GangEnlace del recurso
Publicado 2021
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229535por Yang, Shuai, Li, Hui, Yao, Haipei, Zhang, Yao, Bao, Huiqian, Wu, Liangjing, Zhang, Conghui, Li, Min, Feng, Le, Zhang, Jingfa, Zheng, Zhi, Xu, Guotong, Wang, FangEnlace del recurso
Publicado 2021
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229536por Stoltzfus, Caleb R., Sivakumar, Ramya, Kunz, Leo, Olin Pope, Brandy E., Menietti, Elena, Speziale, Dario, Adelfio, Roberto, Bacac, Marina, Colombetti, Sara, Perro, Mario, Gerner, Michael Y.“…CEA-TCB mono and combination immunotherapy markedly enhanced intra-tumoral cellularity of CD8 T cells, dominantly driven by the expansion of TCF1(-)PD1(+) effector T cells and with more minor increases in TCF1(+)PD1(+) resource CD8 T cells. …”
Publicado 2021
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229537por Fathi, Ibrahim, Imura, Takehiro, Inagaki, Akiko, Nakamura, Yasuhiro, Nabawi, Ayman, Goto, Masafumi“…However, progress with this approach is hindered by intra-vascular blood coagulation that occurs after in vivo implantation of the re-cellularized scaffold, resulting in a short-term graft survival. …”
Publicado 2021
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229538por Schou Nørøxe, Dorte, Flynn, Aidan, Westmose Yde, Christina, Østrup, Olga, Cilius Nielsen, Finn, Skjøth‐Rasmussen, Jane, Brennum, Jannick, Hamerlik, Petra, Weischenfeldt, Joachim, Skovgaard Poulsen, Hans, Lassen, Ulrik“…We present and apply a cellularity correction approach that enables more accurate assessment of TMB in paired tumor samples. …”
Publicado 2021
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229539por David, Michael A., Reiter, Alex J., Dunham, Chelsey L., Castile, Ryan M., Abraham, James A., Iannucci, Leanne E., Shah, Ishani D., Havlioglu, Necat, Chamberlain, Aaron M., Lake, Spencer P.“…Histologically, only SV-D2 modestly reduced capsule fibrosis but maintained elevated cellularity and tissue hypertrophy, and both SV strategies lessened cartilage damage. …”
Publicado 2022
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229540por Hixon, Katherine R., Katz, Dakota B., McKenzie, Jennifer A., Miller, Anna N., Guilak, Farshid, Silva, Matthew J.“…This proof-of-concept study demonstrates the potential for cellularized cryogel scaffolds to enhance the healing of non-unions.…”
Publicado 2022
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