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229641Dysregulation of the endothelial nitric oxide pathway is associated with airway inflammation in COPDpor Csoma, Balázs, Bikov, András, Nagy, Lajos, Tóth, Bence, Tábi, Tamás, Szűcs, Gergő, Komlósi, Zsolt István, Müller, Veronika, Losonczy, György, Lázár, Zsófia“…Serum L-arginine, ADMA, SDMA, nitrite and nitrate were measured and correlated with airway inflammatory markers (fractional exhaled nitric oxide concentration - FENO, sputum nitrite and nitrate, sputum cellularity), serum C-reactive protein - CRP, white blood cell count, lung function and blood gases. …”
Publicado 2019
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229642“…BACKGROUND: Increased macrophage and foam cell apoptosis during early atherogenesis retards plaque progression by impeding foam cell formation, suppressing inflammation and limiting lesion cellularity. Our previous in vitro study in THP1 macrophages demonstrated that Terminalia Arjuna (TA) attenuates dual-specificity phosphatase1 (DUSP1), a key negative regulator of JNK/P38MAPK signaling cascade, the branch also implicated in the UPR (unfolded protein response)-CHOP-mediated apoptotic pathway; however this pathway has not been explored so far in the presence of TA. …”
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229643por Roberts, Jamie Z., Holohan, Caitriona, Sessler, Tamas, Fox, Jennifer, Crawford, Nyree, Riley, Joel S., Khawaja, Hajrah, Majkut, Joanna, Evergren, Emma, Humphreys, Luke M., Ferris, Jennifer, Higgins, Catherine, Espona-Fiedler, Margarita, Moynagh, Paul, McDade, Simon S., Longley, Daniel B.Enlace del recurso
Publicado 2020
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229644por Al-Agha, Mansour, Abushab, Khaled, Quffa, Khetam, Al-Agha, Samy, Alajerami, Yasser, Tabash, Mohammed“…CONCLUSION: The ADC values decrease with an increase in tumor cellularity. Meanwhile, high b value provides better tissue contrast by reflecting more tissue diffusivity. …”
Publicado 2020
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229645por Carmona-Bozo, Julia C., Manavaki, Roido, Woitek, Ramona, Torheim, Turid, Baxter, Gabrielle C., Caracò, Corradina, Provenzano, Elena, Graves, Martin J., Fryer, Tim D., Patterson, Andrew J., Gilbert, Fiona J.“…Tumour hypoxia was assessed using influx rate constant K(i) and hypoxic fractions (%HF), while parameters of vascular function (K(trans), k(ep), v(e), v(p)) and cellularity (ADC) were derived from dynamic contrast-enhanced (DCE) and diffusion-weighted (DW)-MRI, respectively. …”
Publicado 2020
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229646por Mayr, Hermann O., Stoehr, Amelie, Herberger, Katrin T., Haasters, Florian, Bernstein, Anke, Schmal, Hagen, Prall, Wolf C.“…OBJECTIVE: The aim of the present paper is to analyze mid‐term and long‐term alterations of human anterior cruciate ligament (ACL) grafts during the remodeling process with special regards to cellularity, α‐smooth muscle protein (αSMP) expression, and crimp length in comparison to the native ACL. …”
Publicado 2020
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229647por Van Berckelaer, Christophe, Vermeiren, Iris, Vercauteren, Leonie, Rypens, Charlotte, Oner, Gizem, Trinh, Xuan Bich, Tjalma, Wiebren A. A., Broeckx, Glenn, Charafe-Jauffret, Emmanuelle, Van Laere, Steven, Bertucci, François, Colpaert, Cecile, van Dam, Peter A.“…In this group, a high number of sTIL before NACT (HR: 0.23, 95% CI: 0.05–1.02, p = 0.05) was prognostic for a longer OS, while a low number of sTIL after NACT (HR: 0.33, 95% CI: 0.11–0.98, p = 0.046) and a low residual cancer cellularity (HR: 0.20, 95% CI: 0.08–0.52, p < 0.001) was associated with a longer DFS. …”
Publicado 2021
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229648por Adams, Samuel B., Francis, Michael P., Maghdouri-White, Yas, Sori, Nardos, Kemper, Nathan“…Histologically, rabbit tendons showed rapid implant cellularization by 2-8 weeks, along with de novo collagen deposition. …”
Publicado 2022
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229649por Brasil, Oswaldo Ferreira Moura, Kawamuro, Mariana, Marinho, Denise Pardini, Maia, Bruna Trench, Polizelli, Murilo Ubukata, Pipolo, Gabriel, Maia, Natalia Trench, Dompieri, Rodrigo, da Cruz, Natasha Ferreira Santos, Maia, Mauricio“…We hypothesized that higher numbers of white pixels correspond to viable cellularity and better prognoses postoperatively.…”
Publicado 2020
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229650por Gao, Jie, Chen, Yingying, Wu, Pengqiang, Wang, Fujue, Tao, Huan, Shen, Qianqing, Wang, Shuoting, Gong, Shuaige, Zhang, Xue, Zhou, Zhencang, Song, Xianmin, Jia, Yongqian“…Older age, earlier period, male sex, unmarried status, mixed cellularity (MC) and lymphocyte-depletion (LD) histological subtype, and patients received radiotherapy (RT) only were associated with more non-CSD according to binary logistic analysis. …”
Publicado 2021
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229651“…According to the Rye classification, 8% of patients had lymphocyte predominance (LP) subtype, 48% had nodular sclerosis (NS) disease, 37% were of the mixed cellularity (MC) subtype and 7% were of the lymphocyte depletion (LD) subtype. …”
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229652por van Riet, Priscilla, Cahen, Djuna, Hansen, Bettina, Larghi, Alberto, Rindi, Guido, Fellegara, Giovanni, Arcidiacono, Paolo, Doglioni, Claudio, Decarli, Nicola Liberta, Iglesias-Garcia, Julio, Abdulkader, Ihab, Iglesias, Hector Lazare, Kitano, Masayuki, Chikugo, Takaaki, Yasukawa, Satoru, van der Valk, Hans, Biermann, Katharina, Bruno, Marco J.“…Regarding sample quantity, tissue cores were considered present in 70% of cases (κ = 0.37), with a higher level of agreement among expert pathologists (P < 0.001). As for cellularity of the sample, the presence of ≥50% of target cells was reported in 68% of cases (κ = 0.31). …”
Publicado 2017
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229653“…Nodular sclerosis was the most common histology (35.2%), followed by mixed cellularity (21.1%); 36.5% had histology that was not otherwise specified. …”
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229654“…Abdomen and pelvis MRI demonstrated a right ovarian mass primarily solid with high cellularity, measured 4.4 x 3.9 cm; there was at least moderate diffuse enhancement of the mass after contrast administration; adrenal glands were normal. …”
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229655“…In this work, we develop a multiscale, multicellular spatiotemporal model of influenza infection and immune response by combining non-spatial ODE modeling and spatial, cell-based modeling. We employ cellularization, a recently developed method for generating spatial, cell-based, stochastic models from non-spatial ODE models, to generate much of our model from a calibrated ODE model that describes infection, death and recovery of susceptible cells and innate and adaptive responses during influenza infection, and develop models of cell migration and other mechanisms not explicitly described by the ODE model. …”
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229656por Mazzaschi, Giulia, Olivari, Alessandro, Pavarani, Antonio, Lagrasta, Costanza Anna Maria, Frati, Caterina, Madeddu, Denise, Lorusso, Bruno, Dallasta, Silvia, Tommasi, Chiara, Musolino, Antonino, Tiseo, Marcello, Michiara, Maria, Quaini, Federico, Crafa, Pellegrino“…GB cases with high mean ADC at MRI, indicative of low cellularity and soft consistency, exhibited increased OS (median OS = 24 months). …”
Publicado 2022
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229657por Kolberg-Liedtke, Cornelia, Feuerhake, Friedrich, Garke, Madlen, Christgen, Matthias, Kates, Ronald, Grischke, Eva Maria, Forstbauer, Helmut, Braun, Michael, Warm, Mathias, Hackmann, John, Uleer, Christoph, Aktas, Bahriye, Schumacher, Claudia, Kuemmel, Sherko, Wuerstlein, Rachel, Graeser, Monika, Nitz, Ulrike, Kreipe, Hans, Gluz, Oleg, Harbeck, Nadia“…. < 60%) was 0.48 [0.23–0.99]. Low cellularity in 3-week biopsies was the strongest individual predictor for pCR (in both therapy arms), but not for iDFS. …”
Publicado 2022
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229658por Ma, Richard, Schaer, Michael, Chen, Tina, Sisto, Marco, Voigt, Clifford, Nguyen, Joseph, Ying, Lilly, Deng, Xiang-Hua, Rodeo, Scott A.“…Immobilized and isometric grafts had greater femoral bone volume fraction than knees with high-tension grafts at both 3 and 6 weeks (p<0.01 and p<0.001, respectively). Greater cellularity and collagen gaping were seen in loaded ACL graft (those that underwent motion) versus immobilized grafts, particularly within the tibial tunnel. …”
Publicado 2014
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229659por Walsh, William Robert, Bertollo, Nicky, Arciero, Robert A., Stanton, Robert A., Poggie, Robert A.“…Intra articular histology of PLLA- and auto- grafts showed neo-ligamentization at 3 months, increased collagenous deposition and cellularity with time, a reconstituted ACL at 1 year, and continued maturation. …”
Publicado 2015
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229660por Thair, Simone A, He, Yudong, Hasin-Brumshtein, Yehudit, Sakaram, Suraj, Pandya, Rushika R, Toh, Jiaying, Rawling, David C, Remmel, Melissa, Coyle, Sabrina, Dalekos, George, Koutsodimitropoulos, Ioannis, Vlachogianni, Glykeria, Gkeka, Eleni, Karakike, Eleni, Damoraki, Georgia, Antonakos, Nikolaos, Degree, Medical, Khatri, Purvesh, Giamarellos, Evangelos J, Sweeney, Timothy“…Figure 1 [Image: see text] Figure 2 [Image: see text] Figure 3 [Image: see text] CONCLUSION: The concordant and discordant responses mapped here provide a window to explore the pathophysiology of COVID-19 vs other viral infections and show clear differences in signaling pathways and cellularity as part of the host response to SARS-CoV-2. …”
Publicado 2020
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