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681por Reekie, Ian R., Sharma, Srilakshmi, Foers, Andrew, Sherlock, Jonathan, Coles, Mark C., Dick, Andrew D., Denniston, Alastair K., Buckley, Christopher D.“…Despite being grouped together anatomically, the iris, ciliary body and choroid are distinct functionally, and inflammatory diseases may affect only one part and not the others. Cellular structure of tissues direct their function, and understanding the cellular basis of the immune environment of a tissue in health, the “steady state” on which the perturbations of disease are superimposed, is vital to understanding the pathogenesis of those diseases. …”
Publicado 2021
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682por Bonitto, Kenya, Sarathy, Kirthana, Atai, Kaiser, Mitra, Mithun, Coller, Hilary A.Enlace del recurso
Publicado 2021
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683por Mohiuddin, Sayed Golam, Ghosh, Sreyashi, Ngo, Han G., Sensenbach, Shayne, Karki, Prashant, Dewangan, Narendra K., Angardi, Vahideh, Orman, Mehmet A.“…Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells that enables survival under stressful conditions by recycling essential energy molecules. …”
Publicado 2021
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684por Pijnenborg, Johan F. A., Rossing, Emiel, Merx, Jona, Noga, Marek J., Titulaer, Willem H. C., Eerden, Nienke, Veizaj, Raisa, White, Paul B., Lefeber, Dirk J., Boltje, Thomas J.“…We demonstrate that cell permeable fluorinated rhamnose 1-phosphate derivatives (Fucotrim I & II) are metabolic prodrugs that are metabolized to their respective GDP-mannose derivatives and efficiently inhibit cellular fucosylation.…”
Publicado 2021
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685por del Toro, Neylen, Lessard, Frédéric, Bouchard, Jacob, Mobasheri, Nasrin, Guillon, Jordan, Igelmann, Sebastian, Tardif, Sarah, Buffard, Tony, Bourdeau, Véronique, Brakier-Gingras, Léa, Ferbeyre, Gerardo“…Although translation errors could also expand the cellular proteome, their role in cancer biology remains poorly understood. …”
Publicado 2021
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686por Edel, Gabriëla G., Schaaf, Gerben, Wijnen, Rene M. H., Tibboel, Dick, Kardon, Gabrielle, Rottier, Robbert J.“…CDH is a complex congenital disorder with multifactorial etiology consisting of genetic, cellular and mechanical factors. This review explores the cellular origin of CDH pathogenesis in the diaphragm and lungs and describes recent developments in basic and translational CDH research.…”
Publicado 2021
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687“…Cellular senescence is a complex and multistep biological process which cells can undergo in response to different stresses. …”
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688“…As more research is being conducted, the microbiome field is shifting from simple descriptive analysis of commensal compositions to more molecular, cellular, and functional studies. Insight into these mechanisms is of paramount importance for understanding and modulating the effects that microbiota, probiotics, and their derivatives exert on host health.…”
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689por Kowalczyk, Mateusz, Kowalczyk, Edward, Kwiatkowski, Paweł, Łopusiewicz, Łukasz, Talarowska, Monika, Sienkiewicz, MonikaEnlace del recurso
Publicado 2021
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690por Chakrabarty, Pulasta, Gupta, Pallavi, Illath, Kavitha, Kar, Srabani, Nagai, Moeto, Tseng, Fan-Gang, Santra, Tuhin Subhra“…The past two decades have consequently seen a tremendous boost in mechanoporation-based research for intracellular delivery and cellular analysis. This article provides a brief review of the most recent developments on microfluidic-based mechanoporation strategies such as microinjection, nanoneedle arrays, cell-squeezing, and hydroporation techniques with their working principle, device fabrication, cellular delivery, and analysis. …”
Publicado 2021
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691por Zammouri, Jamila, Vatier, Camille, Capel, Emilie, Auclair, Martine, Storey-London, Caroline, Bismuth, Elise, Mosbah, Héléna, Donadille, Bruno, Janmaat, Sonja, Fève, Bruno, Jéru, Isabelle, Vigouroux, Corinne“…Diagnosis, based on clinical and metabolic investigations, and on genetic analyses, is of major importance to adapt medical care and genetic counseling. Molecular and cellular bases of these syndromes involve, among others, altered adipocyte differentiation, structure and/or regulation of the adipocyte lipid droplet, and/or premature cellular senescence. …”
Publicado 2022
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693“…Here, we review the landscape of cellular immunotherapy for HCC, and outline how advanced engineering solutions may further enhance this therapeutic approach. …”
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694por Liu, Rui-Ming“…The mechanism underlying the aging-related susceptibility to LOAD is unknown. Cellular senescence, a state of permanent cell growth arrest, is believed to contribute importantly to aging and aging-related diseases, including AD. …”
Publicado 2022
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695“…Interestingly, multi-systemic DM manifestations, including muscle weakness, cognitive impairment, cataract, and frontal baldness, resemble premature aging. Furthermore, cellular senescence, a critical contributor to aging, is suggested to play a key role in DM cellular pathophysiology. …”
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696por Sheldrake, A. Rupert“…If so, our understanding of cellular senescence, rejuvenation and potential immortality could be brought together in a new synthesis, which I call the cellular rejuvenation hypothesis: damaged cell constituents build up in all cells, but cells can be rejuvenated either by growth and cell division or, in ‘immortal’ cell lines, by excreting damaged cell constituents. …”
Publicado 2022
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697“…Organelles can also actively communicate with each other to maintain cellular homeostasis via the vesicular trafficking pathways and membrane contact sites (MCSs), which allow the exchange of metabolites and other information required for normal cellular physiology. …”
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699por Duclut, Charlie, Paijmans, Joris, Inamdar, Mandar M., Modes, Carl D., Jülicher, Frank“…In this paper, we use an anisotropic vertex model to study T1 rearrangements in polygonal cellular networks. We consider two different physical realizations of the active anisotropic stresses: (i) anisotropic bond tension and (ii) anisotropic cell stress. …”
Publicado 2022
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700Materias: “…Cellular Neuroscience…”
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