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121por Dalmasso, Giovanni, Marin Zapata, Paula Andrea, Brady, Nathan Ryan, Hamacher-Brady, Anne“…Mitochondria are semi-autonomous organelles that supply energy for cellular biochemistry through oxidative phosphorylation. …”
Publicado 2017
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122“…In neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS), such mutations are known to result in protein misfolding, which in turn results in the formation of intracellular aggregates cellular dysfunction and eventual neuronal death. The exact cellular pathology of ALS and other neurodegenerative diseases has been elusive and thus, hindering the development of effective therapies. …”
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123“…As an organ with a highly heterogenous cellular composition, the brain has a bioenergetic system that is more complex than peripheral tissues. …”
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124por Manevski, Marko, Muthumalage, Thivanka, Devadoss, Dinesh, Sundar, Isaac K., Wang, Qixin, Singh, Kameshwar P., Unwalla, Hoshang J., Chand, Hitendra S., Rahman, Irfan“…As the central hubs of cell metabolism and energetics, mitochondria integrate cellular responses and interorganellar signaling pathways to maintain cellular and extracellular redox status and the cellular senescence that dictate the lung tissue responses. …”
Publicado 2020
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135por Beckerman, Martin“…This is because, in large measure, when the cellular signaling pathways responsible for maintaining homeostasis and health of the body become dysregulated, they generate equally stable disease states. …”
Publicado 2009
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137por Adamatzky, Andrew“…Conway's Game of Life became the most programmed solitary game and the most known cellular automaton. The book brings together results of forty years of study into computational…”
Publicado 2010
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138“…To address this need, MIMO Communication for Cellular Networks presents a systematic description of MIMO technology classes and a framework for MIMO system design that takes into account the essential physical-layer features of practical cellular networks. …”
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