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861por Jenabian, Mohammad-Ali, Talla, Frédéric, Talla, Perrine, Mbopi-Kéou, François-Xavier, Charpentier, Charlotte, Kane, Coumba Toure, Bélec, Laurent“…Discrepancies between the results of HIV viral load assays and molecular tests should alert clinicians and virologists to the possibility of infection by an atypical variant virus, especially in Central Africa where very broad HIV-1 genetic diversity exists.…”
Publicado 2015
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862por Murn, Campbell, Mundy, Peter, Virani, Munir Z., Borello, Wendy D., Holloway, Graham J., Thiollay, Jean‐Marc“…Eastern Africa is estimated to contain 721 nests, Central Africa 548 nests, Southern Africa 468 nests, and West Africa 156 nests. …”
Publicado 2016
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863por Stern, Daniel, Pauly, Diana, Zydek, Martin, Miller, Lilija, Piesker, Janett, Laue, Michael, Lisdat, Fred, Dorner, Martin B., Dorner, Brigitte G., Nitsche, Andreas“…Infections often occur in rural areas lacking proper diagnostic infrastructure as exemplified by monkeypox, which is endemic in Western and Central Africa. While PCR detection requires demanding equipment and is restricted to genome detection, the evidence of virus particles can complement or replace PCR. …”
Publicado 2016
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864por Pardo-Seco, Jacobo, Heinz, Tanja, Taboada-Echalar, Patricia, Martinón-Torres, Federico, Salas, Antonio“…RESULTS: The data indicate that these two genomes constitute a complex mosaic of ancestries that is approximately 80 % of recent African origin; the remaining ~20 % being European and Native American. West-Central Africa contributed most of the African ancestry to ‘Afro-Bolivians’, and this component is related to populations living along the Atlantic coast (i.e. …”
Publicado 2016
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865por Raguin, Gilles“…Launched in 2002, the ESTHER (Ensemble pour une Solidarite Thérapeutique Hospitalière En Reseau) initiative has grown from small projects with a focus on access to antiretroviral treatment in a limited number of West African countries at its outset into a large and comprehensive HIV/AIDS-control system in Western and Central Africa. The partnership’s rapid achievements in the fight against HIV/AIDS, combined with the comprehensive and long-term approach to countries’ health care needs, suggest that this “twinning” and medical mentoring model can and should be duplicated and developed to address the ever more pressing demand for response to global health needs in low resource countries.…”
Publicado 2016
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866por Meyin A Ebong, Solange, Petit, Elsa, Le Gall, Philippe, Chen, Ping-Ping, Nieser, Nico, Guilbert, Eric, Njiokou, Flobert, Marsollier, Laurent, Guégan, Jean-François, Pluot-Sigwalt, Dominique, Eyangoh, Sara, Harry, Myriam“…Aquatic and semi-aquatic bugs (Heteroptera) represent a remarkable diversity and a resurging interest has been given to documenting at the species level these insects inhabiting Cameroon in Central Africa due to their potential implication in the transmission of the bacterium Mycobacterium ulcerans, the causal agent of Buruli ulcer, an emerging human disease. …”
Publicado 2016
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867por Nakouné, Emmanuel, Kamgang, Basile, Berthet, Nicolas, Manirakiza, Alexandre, Kazanji, Mirdad“…Although the cycle of RVFV infection in savannah regions is well documented, its distribution in forest areas in central Africa has been poorly investigated. METHODOLOGY/PRINCIPAL FINDINGS: To evaluate current circulation of RVFV among livestock and humans living in the Central African Republic (CAR), blood samples were collected from sheep, cattle, and goats and from people at risk, such as stock breeders and workers in slaughterhouses and livestock markets. …”
Publicado 2016
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868por Simons, Robin R. L., Horigan, Verity, Gale, Paul, Kosmider, Rowena D., Breed, Andrew C., Snary, Emma L.“…Bat-borne viruses have been linked to a number of zoonotic diseases; in 2014 there have been human cases of Nipah virus (NiV) in Bangladesh and Ebola virus in West and Central Africa. Here we describe a model designed to provide initial quantitative predictions of the risk of entry of such viruses to European Union (EU) Member States (MSs) through four routes: human travel, legal trade (e.g. fruit and animal products), live animal movements and illegal importation of bushmeat. …”
Publicado 2016
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869por Mossoro-Kpinde, CD, Jenabian, MA, Gody, JC, Robin, L, Talla, P, Longo, JDD, Grésenguet, G, Belec, L“…The aim of this study was to evaluate the performances of the COBAS(®) AmpliPrep/COBAS(®) (CAP/CTM) HIV-1 Qualitative assays to detect the broad range of HIV-1 variants circulating in Central Africa and compare to the outgoing CAP/CTM HIV-1 Quantitative test v2.0 (Roche Molecular Systems), chosen as reference gold standard molecular assay. …”
Publicado 2016
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870“…The 1014F kdr mutation originally described only in West Africa is spreading to East Africa while the 1014S kdr mutation originally described in East Africa, is spreading to West and Central Africa. However, the East- kdr mutation has not been reported in Côte d'Ivoire so far. …”
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871por Vandelannoote, Koen, Meehan, Conor J., Eddyani, Miriam, Affolabi, Dissou, Phanzu, Delphin Mavinga, Eyangoh, Sara, Jordaens, Kurt, Portaels, Françoise, Mangas, Kirstie, Seemann, Torsten, Marsollier, Laurent, Marion, Estelle, Chauty, Annick, Landier, Jordi, Fontanet, Arnaud, Leirs, Herwig, Stinear, Timothy P., de Jong, Bouke C.“…Cases are reported around the world but the rural regions of West and Central Africa are most affected. How BU is transmitted and spreads has remained a mystery, even though the causative agent, Mycobacterium ulcerans, has been known for more than 70 years. …”
Publicado 2017
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872por Kamgno, Joseph, Pion, Sébastien D., Chesnais, Cédric B., Bakalar, Matthew H., D'Ambrosio, Michael V., Mackenzie, Charles D., Nana-Djeunga, Hugues C., Gounoue-Kamkumo, Raceline, Njitchouang, Guy-Roger, Nwane, Philippe, Tchatchueng-Mbouga, Jules B., Wanji, Samuel, Stolk, Wilma A., Fletcher, Daniel A., Klion, Amy D., Nutman, Thomas B., Boussinesq, Michel“…BACKGROUND: Implementation of ivermectin-based community treatment for onchocerciasis or lymphatic filariasis elimination has been delayed in Central Africa because of severe adverse events (SAEs), including death, in people with high levels of circulating Loa loa microfilariae (mf). …”
Publicado 2017
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873por Lang, Colleen Walsh“…Children’s access to antiretroviral treatment (ART) remains low (est. 63% in east/central Africa), and even with access, long-term adherence is difficult. …”
Publicado 2017
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874por Ndede, Isaac, Mining, Simeon K., Patel, Kirtika, Wanjala, Fredrick M., Chumba, David, Tenge, Constance“…OBJECTIVE: Burkitt’s lymphoma (BL) is a common aggressive non-Hodgkin’s lymphoma in East and Central Africa among children. Persistent infections with Epstein Barr virus or Plasmodium falciparum are associated with immune hyperstimulation. …”
Publicado 2017
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875por Kelly-Hope, Louise A., Stanton, Michelle C., Zouré, Honorat G. M., Kinvi, Boniface E., Mikhailov, Alexei, Tekle, Afework, King, Jonathan D.“…The co-distribution of Loa loa in Central Africa poses a significant barrier to the expansion of the MDA due to risk of severe adverse events (SAEs) associated with the drug ivermectin that is routinely used. …”
Publicado 2017
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876“…Evidence of gene flow was strongest for SNP-based groups occurring in central Africa. Comparison of the mtCOI and SNP identities of sampled insects provided a strong indication that hybrid populations are emerging in parts of Africa recently affected by the severe CMD pandemic. …”
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877por Workneh, Meklit, Katz, Morgan J, Lamorde, Mohammed, Cosgrove, Sara E, Manabe, Yukari C“…Eight studies were from Western and Central Africa, 8 from Eastern Africa, and 4 from Southern Africa. …”
Publicado 2017
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878por Cashman, Kathleen A., Wilkinson, Eric R., Shaia, Carl I., Facemire, Paul R., Bell, Todd M., Bearss, Jeremy J., Shamblin, Joshua D., Wollen, Suzanne E., Broderick, Kate E., Sardesai, Niranjan Y., Schmaljohn, Connie S.“…Lassa virus (LASV) is an ambisense RNA virus in the Arenaviridae family and is the etiological agent of Lassa fever, a severe hemorrhagic disease endemic to West and Central Africa.(1,2) There are no US Food and Drug Administration (FDA)-licensed vaccines available to prevent Lassa fever.(1,2) in our previous studies, we developed a gene-optimized DNA vaccine that encodes the glycoprotein precursor gene of LASV (Josiah strain) and demonstrated that 3 vaccinations accompanied by dermal electroporation protected guinea pigs from LASV-associated illness and death. …”
Publicado 2017
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879por Tanga, Chrysantus Mbi, Khamis, Fathiya Mbarak, Tonnang, Henri E. Z., Rwomushana, Ivan, Mosomtai, Gladys, Mohamed, Samira A., Ekesi, Sunday“…Globally, the model highlights the substantial invasion risk posed by C. rosa and C. quilicii to cropping regions in the Americas, Australia, India, China, Southeast Asia, Europe, and West and Central Africa. However, the proportion of the regions predicted to be climatically suitable for both pests is narrower for C. rosa in comparison with C. quilicii, suggesting that C. quilicii will be more tolerant to a wider range of climatic conditions than C. rosa. …”
Publicado 2018
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880por Motta, Paolo, Handel, Ian G., Rydevik, Gustaf, Hamman, Saidou M., Ngwa, Victor Ngu, Tanya, Vincent N., Morgan, Kenton L., Bronsvoort, Barend M. deC., Porphyre, Thibaud“…Ultimately, our model gives a large scale overview of drivers of cattle price formation in Cameroon and to our knowledge is the first study of this scale in Central Africa. Our findings represent an important milestone in designing efficient and sustainable animal health management programme in Cameroon and ensure livelihood sustainability for rural households.…”
Publicado 2018
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