A Phase I, First-in-Human Study of PRL3-zumab in Advanced, Refractory Solid Tumors and Hematological Malignancies

por Chee, Cheng E., Ooi, Melissa, Lee, Soo-Chin, Sundar, Raghav, Heong, Valerie, Yong, Wei-Peng, Ng, Chin Hin, Wong, Andrea, Lim, Joline S. J., Tan, David S. P., Soo, Ross, Tan, Joshua T. C., Yang, Song, Thura, Min, Al-Aidaroos, Abdul Qader, Chng, Wee Joo, Zeng, Qi, Goh, Boon-Cher
Publicado 2023

Cost-minimization analysis of oral versus intravenous antibiotic treatment for Klebsiella pneumoniae liver abscess

por Yoong, Joanne, Yuen, Kah Hung, Molton, James S., Ding, Ying, Cher, Boon Piang, Chan, Monica, Kalimuddin, Shirin, Oon, Jolene, Young, Barnaby, Low, Jenny, Salada, Brenda M. A., Lee, Tau Hong, Wijaya, Li Min, Fisher, Dale, Izharuddin, Ezlyn, Wei, Yuan, Phillips, Rachel, Moorakonda, Rajesh, Lye, David C., Archuleta, Sophia
Publicado 2023

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer

por Tsui, Dana Wai Yi, Murtaza, Muhammed, Wong, Alvin Seng Cheong, Rueda, Oscar M, Smith, Christopher G, Chandrananda, Dineika, Soo, Ross A, Lim, Hong Liang, Goh, Boon Cher, Caldas, Carlos, Forshew, Tim, Gale, Davina, Liu, Wei, Morris, James, Marass, Francesco, Eisen, Tim, Chin, Tan Min, Rosenfeld, Nitzan
Publicado 2018

Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma

por Chen, Ye, Xu, Liang, Mayakonda, Anand, Huang, Mo-Li, Kanojia, Deepika, Tan, Tuan Zea, Dakle, Pushkar, Lin, Ruby Yu-Tong, Ke, Xin-Yu, Said, Jonathan W., Chen, Jianxiang, Gery, Sigal, Ding, Ling-Wen, Jiang, Yan-Yi, Pang, Angela, Puhaindran, Mark Edward, Goh, Boon Cher, Koeffler, H. Phillip
Publicado 2019

FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway

por Yeo, Mei Shi, Vijay Subhash, Vinod, Suda, Kazuto, Emrah Balcıoğlu, Hayri, Zhou, Siqin, Thuya, Win Lwin, Loh, Xin Yi, Jammula, Sriganesh, Peethala, Praveen C., Tan, Shi Hui, Xie, Chen, Wong, Foong Ying, Ladoux, Benoit, Ito, Yoshiaki, Yang, Henry, Goh, Boon Cher, Wang, Lingzhi, Yong, Wei Peng
Publicado 2019

Whole Exome Sequencing of Multi-Regional Biopsies from Metastatic Lesions to Evaluate Actionable Truncal Mutations Using a Single-Pass Percutaneous Technique

por Heong, Valerie, Tay, Darwin, Goh, Shane Ee, Wee, Bernard, Tan, Tuan Zea, Soo, Ross, Pang, Brendan, Lim, Diana, Gopinathan, Anil, Ow, Samuel, Chee, Cheng Ean, Goh, Boon Cher, Lee, Soo Chin, Yong, Wei Peng, Wong, Andrea, Omar, Mohamed Feroz Mohd, Soong, Richie, Tan, David S.P.
Publicado 2020

Consensus report from the 9(th) International Forum for Liver Magnetic Resonance Imaging: applications of gadoxetic acid-enhanced imaging

por Koh, Dow-Mu, Ba-Ssalamah, Ahmed, Brancatelli, Giuseppe, Fananapazir, Ghaneh, Fiel, M. Isabel, Goshima, Satoshi, Ju, Sheng-Hong, Kartalis, Nikolaos, Kudo, Masatoshi, Lee, Jeong Min, Murakami, Takamichi, Seidensticker, Max, Sirlin, Claude B., Tan, Cher Heng, Wang, Jin, Yoon, Jeong Hee, Zeng, Mengsu, Zhou, Jian, Taouli, Bachir
Publicado 2021

Immunohistochemistry study of tumor vascular normalization and anti-angiogenic effects of sunitinib versus bevacizumab prior to dose-dense doxorubicin/cyclophosphamide chemotherapy...

por Yadav, Kritika, Lim, Joline, Choo, Joan, Ow, Samuel Guan Wei, Wong, Andrea, Lee, Matilda, Chan, Ching Wan, Hartman, Mikael, Lim, Siew Eng, Ngoi, Natalie, Tang, Siau Wei, Ang, Yvonne, Chan, Gloria, Chong, Wan Qin, Tan, Hon Lyn, Tan, Sing Huang, Goh, Boon Cher, Lee, Soo Chin
Publicado 2021

Glucuronidation by UGT1A1 Is the Dominant Pathway of the Metabolic Disposition of Belinostat in Liver Cancer Patients

por Wang, Ling-Zhi, Ramírez, Jacqueline, Yeo, Winnie, Chan, Mei-Yi Michelle, Thuya, Win-Lwin, Lau, Jie-Ying Amelia, Wan, Seow-Ching, Wong, Andrea Li-Ann, Zee, Ying-Kiat, Lim, Robert, Lee, Soo-Chin, Ho, Paul C., Lee, How-Sung, Chan, Anthony, Ansher, Sherry, Ratain, Mark J., Goh, Boon-Cher
Publicado 2013

Correction: Glucuronidation by UGT1A1 Is the Dominant Pathway of the Metabolic Disposition of Belinostat in Liver Cancer Patients

por Wang, Ling-Zhi, Ramírez, Jacqueline, Yeo, Winnie, Chan, Mei-Yi Michelle, Thuya, Win-Lwin, Lau, Jie-Ying Amelia, Wan, Seow-Ching, Wong, Andrea Li-Ann, Zee, Ying-Kiat, Lim, Robert, Lee, Soo-Chin, Ho, Paul C., Lee, How-Sung, Chan, Anthony, Ansher, Sherry, Ratain, Mark J., Goh, Boon-Cher
Publicado 2014

Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial

por Syn, Nicholas L., Wong, Andrea Li-Ann, Lee, Soo-Chin, Teoh, Hock-Luen, Yip, James Wei Luen, Seet, Raymond CS, Yeo, Wee Tiong, Kristanto, William, Bee, Ping-Chong, Poon, LM, Marban, Patrick, Wu, Tuck Seng, Winther, Michael D., Brunham, Liam R., Soong, Richie, Tai, Bee-Choo, Goh, Boon-Cher
Publicado 2018

An enhanced CRISPR repressor for targeted mammalian gene regulation

por Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T, Davidsohn, Noah, Ebrahimkhani, Mo R., Collins, James J., Lewis, Nathan E., Kiani, Samira, Church, George M.
Publicado 2018

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

por Capper, David, von Deimling, Andreas, Brandes, Alba A., Carpentier, Antoine F., Kesari, Santosh, Sepulveda-Sanchez, Juan M., Wheeler, Helen R., Chinot, Olivier, Cher, Lawrence, Steinbach, Joachim P., Specenier, Pol, Rodon, Jordi, Cleverly, Ann, Smith, Claire, Gueorguieva, Ivelina, Miles, Colin, Guba, Susan C., Desaiah, Durisala, Estrem, Shawn T., Lahn, Michael M., Wick, Wolfgang
Publicado 2017

Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span

por Kaverina, Natalya, Schweickart, R. Allen, Chan, Gek Cher, Maggiore, Joseph C., Eng, Diana G., Zeng, Yuting, McKinzie, Sierra R., Perry, Hannah S., Ali, Adilijiang, O’Connor, Christopher, Pereira, Beatriz Maria Veloso, Theberge, Ashleigh B., Vaughan, Joshua C., Loretz, Carol J., Chang, Anthony, Hukriede, Neil A., Bitzer, Markus, Pippin, Jeffrey W., Wessely, Oliver, Shankland, Stuart J.
Publicado 2023

A Phase II Study of Osimertinib in Patients with Advanced-Stage Non-Small Cell Lung Cancer following Prior Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) The...

por Ang, Yvonne L. E., Zhao, Xiaotian, Reungwetwattana, Thanyanan, Cho, Byoung-Chul, Liao, Bin-Chi, Yeung, Rebecca, Loong, Herbert H., Kim, Dong-Wan, Yang, James Chih-Hsin, Lim, Sun Min, Ahn, Myung-Ju, Lee, Se-Hoon, Suwatanapongched, Thitiporn, Kongchauy, Kanchaporn, Ou, Qiuxiang, Yu, Ruoying, Tai, Bee Choo, Goh, Boon Cher, Mok, Tony S. K., Soo, Ross A.
Publicado 2023

Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

por Tan, Tuan Zea, Miow, Qing Hao, Huang, Ruby Yun-Ju, Wong, Meng Kang, Ye, Jieru, Lau, Jieying Amelia, Wu, Meng Chu, Bin Abdul Hadi, Luqman Hakim, Soong, Richie, Choolani, Mahesh, Davidson, Ben, Nesland, Jahn M, Wang, Ling-Zhi, Matsumura, Noriomi, Mandai, Masaki, Konishi, Ikuo, Goh, Boon-Cher, Chang, Jeffrey T, Thiery, Jean Paul, Mori, Seiichi
Publicado 2013

A study of type-specific HPV natural history and implications for contemporary cervical cancer screening programs

por Demarco, Maria, Hyun, Noorie, Carter-Pokras, Olivia, Raine-Bennett, Tina R., Cheung, Li, Chen, Xiaojian, Hammer, Anne, Campos, Nicole, Kinney, Walter, Gage, Julia C., Befano, Brian, Perkins, Rebecca B., He, Xin, Dallal, Cher, Chen, Jie, Poitras, Nancy, Mayrand, Marie-Helene, Coutlee, Francois, Burk, Robert D., Lorey, Thomas, Castle, Philip E., Wentzensen, Nicolas, Schiffman, Mark
Publicado 2020

Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers

por Loo, Ser Yue, Syn, Nicholas L., Koh, Angele Pei-Fern, Teng, Janet Cheng-Fei, Deivasigamani, Amudha, Tan, Tuan Zea, Thike, Aye Aye, Vali, Shireen, Kapoor, Shweta, Wang, Xiaoyuan, Wang, Jiong Wei, Tan, Puay Hoon, Yip, George W., Sethi, Gautam, Huang, Ruby Yun-Ju, Hui, Kam Man, Wang, Lingzhi, Goh, Boon Cher, Kumar, Alan Prem
Publicado 2021

Discovery of a 2′-Fluoro,2′-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice

por LeCher, Julia C., Zandi, Keivan, Costa, Vivian Vasconcelos, Amblard, Franck, Tao, Sijia, Patel, Dharmeshkumar, Lee, Sujin, da Silva Santos, Felipe Rocha, Goncalves, Matheus Rodrigues, Queroz-Junior, Celso Martins, Marim, Fernanda Martins, Musall, Katie, Goh, Shu Ling, McBrayer, Tamara, Downs-Bowen, Jessica, De, Ramyani, Azadi, Niloufar, Kohler, James, Teixeira, Mauro Martins, Schinazi, Raymond F.
Publicado 2022