Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

por Puah, Ser Hon, Young, Barnaby Edward, Chia, Po Ying, Ho, Vui Kian, Loh, Jiashen, Gokhale, Roshni Sadashiv, Tan, Seow Yen, Sewa, Duu Wen, Kalimuddin, Shirin, Tan, Chee Keat, Pada, Surinder K. M. S., Cove, Matthew Edward, Chai, Louis Yi Ann, Parthasarathy, Purnima, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Ling, Li Min, Abisheganaden, John A., Lee, Vernon J. M., Tan, Cher Heng, Lin, Raymond T. P., Leo, Yee Sin, Lye, David C., Yeo, Tsin Wen
Publicado 2021

A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in...

por Ho, Jingshan, Heong, Valerie, Peng Yong, Wei, Soo, Ross, Ean Chee, Cheng, Wong, Andrea, Sundar, Raghav, Liang Thian, Yee, Gopinathan, Anil, Yan Pang, Mei, Koe, Priscillia, Nathan Jeraj, Santhiay, Pyar Soe, Phyu, Yar Soe, Mu, Tang, Tiffany, Ng, Matthew C.H., Tai, David W.M., Tan, Tira J.Y., Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Chin Lee, Soo, Tan, Daniel S.W., Cher Goh, Boon, Tan, David S.P.
Publicado 2022

FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites

por Thuya, Win Lwin, Kong, Li Ren, Syn, Nicholas L., Ding, Ling-Wen, Cheow, Esther Sok Hwee, Wong, Regina Tong Xin, Wang, Tingting, Goh, Robby Miguel Wen-Jing, Song, Hongyan, Jayasinghe, Migara K., Le, Minh TN, Hu, Jian Cheng, Yong, Wei-Peng, Lee, Soo-Chin, Wong, Andrea Li-Ann, Sethi, Gautam, Hung, Huynh The, Ho, Paul Chi-Lui, Thiery, Jean-Paul, Sze, Siu Kwan, Guo, Tiannan, Soo, Ross A., Yang, Henry, Lim, Yaw Chyn, Wang, Lingzhi, Goh, Boon-Cher
Publicado 2023

The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disea...

por Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Barbara, Cristina, Buist, A. Sonia, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Erhabor, Gregory E., Franssen, Frits M. E., Al Ghobain, Mohammed, Gislason, Thorarinn, Janson, Christer, Kocabaş, Ali, Mannino, David, Marks, Guy, Mortimer, Kevin, Nafees, Asaad Ahmed, Obaseki, Daniel, Paraguas, Stefanni Nonna M., Loh, Li Cher, Rashid, Abdul, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C., Wouters, Emiel F. M., Abozid, Hazim, Mueller, Alexander, Burney, Peter, Amaral, Andre F. S.
Publicado 2023

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

por Randzavola, Lyra O, Mortimer, Paige M, Garside, Emma, Dufficy, Elizabeth R, Schejtman, Andrea, Roumelioti, Georgia, Yu, Lu, Pardo, Mercedes, Spirohn, Kerstin, Tolley, Charlotte, Brandt, Cordelia, Harcourt, Katherine, Nichols, Esme, Nahorski, Mike, Woods, Geoff, Williamson, James C, Suresh, Shreehari, Sowerby, John M, Matsumoto, Misaki, Santos, Celio XC, Kiar, Cher Shen, Mukhopadhyay, Subhankar, Rae, William M, Dougan, Gordon J, Grainger, John, Lehner, Paul J, Calderwood, Michael A, Choudhary, Jyoti, Clare, Simon, Speak, Anneliese, Santilli, Giorgia, Bateman, Alex, Smith, Kenneth GC, Magnani, Francesca, Thomas, David C
Publicado 2022

Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study

por Ratanachina, Jate, Amaral, Andre F.S., De Matteis, Sara, Lawin, Herve, Mortimer, Kevin, Obaseki, Daniel O., Harrabi, Imed, Denguezli, Meriam, Wouters, Emiel F.M., Janson, Christer, Nielsen, Rune, Gulsvik, Amund, Cherkaski, Hamid Hacene, Mejza, Filip, Mahesh, Padukudru Anand, Elsony, Asma, Ahmed, Rana, Tan, Wan, Loh, Li Cher, Rashid, Abdul, Studnicka, Michael, Nafees, Asaad A., Seemungal, Terence, Aquart-Stewart, Althea, Al Ghobain, Mohammed, Zheng, Jinping, Juvekar, Sanjay, Salvi, Sundeep, Jogi, Rain, Mannino, David, Gislason, Thorarinn, Buist, A. Sonia, Cullinan, Paul, Burney, Peter
Publicado 2023

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

por Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Publicado 2019

Statistical Process Control Charts for Monitoring Next-Generation Sequencing and Bioinformatics Turnaround in Precision Medicine Initiatives

por Jain, Sneha Rajiv, Sim, Wilson, Ng, Cheng Han, Chin, Yip Han, Lim, Wen Hui, Syn, Nicholas L., Kamal, Nur Haidah Bte Ahmad, Gupta, Mehek, Heong, Valerie, Lee, Xiao Wen, Sapari, Nur Sabrina, Koh, Xue Qing, Isa, Zul Fazreen Adam, Ho, Lucius, O’Hara, Caitlin, Ulagapan, Arvindh, Gu, Shi Yu, Shroff, Kashyap, Weng, Rei Chern, Lim, Joey S. Y., Lim, Diana, Pang, Brendan, Ng, Lai Kuan, Wong, Andrea, Soo, Ross Andrew, Yong, Wei Peng, Chee, Cheng Ean, Lee, Soo-Chin, Goh, Boon-Cher, Soong, Richie, Tan, David S.P.
Publicado 2021

Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

por Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Publicado 2021

Chronic airflow obstruction and ambient particulate air pollution

por Amaral, Andre F S, Burney, Peter G J, Patel, Jaymini, Minelli, Cosetta, Mejza, Filip, Mannino, David M, Seemungal, Terence A R, Mahesh, Padukudru Anand, Lo, Li Cher, Janson, Christer, Juvekar, Sanjay, Denguezli, Meriam, Harrabi, Imed, Wouters, Emiel F M, Cherkaski, Hamid, Mortimer, Kevin, Jogi, Rain, Bateman, Eric D, Fuertes, Elaine, Al Ghobain, Mohammed, Tan, Wan, Obaseki, Daniel O, El Sony, Asma, Studnicka, Michael, Aquart-Stewart, Althea, Koul, Parvaiz, Lawin, Herve, Nafees, Asaad Ahmed, Awopeju, Olayemi, Erhabor, Gregory E, Gislason, Thorarinn, Welte, Tobias, Gulsvik, Amund, Nielsen, Rune, Gnatiuc, Louisa, Kocabas, Ali, Marks, Guy B, Sooronbaev, Talant, Mbatchou Ngahane, Bertrand Hugo, Barbara, Cristina, Buist, A Sonia
Publicado 2021

Genotype–phenotype correlations and novel molecular insights into the DHX30-associated neurodevelopmental disorders

por Mannucci, Ilaria, Dang, Nghi D. P., Huber, Hannes, Murry, Jaclyn B., Abramson, Jeff, Althoff, Thorsten, Banka, Siddharth, Baynam, Gareth, Bearden, David, Beleza-Meireles, Ana, Benke, Paul J., Berland, Siren, Bierhals, Tatjana, Bilan, Frederic, Bindoff, Laurence A., Braathen, Geir Julius, Busk, Øyvind L., Chenbhanich, Jirat, Denecke, Jonas, Escobar, Luis F., Estes, Caroline, Fleischer, Julie, Groepper, Daniel, Haaxma, Charlotte A., Hempel, Maja, Holler-Managan, Yolanda, Houge, Gunnar, Jackson, Adam, Kellogg, Laura, Keren, Boris, Kiraly-Borri, Catherine, Kraus, Cornelia, Kubisch, Christian, Le Guyader, Gwenael, Ljungblad, Ulf W., Brenman, Leslie Manace, Martinez-Agosto, Julian A., Might, Matthew, Miller, David T., Minks, Kelly Q., Moghaddam, Billur, Nava, Caroline, Nelson, Stanley F., Parant, John M., Prescott, Trine, Rajabi, Farrah, Randrianaivo, Hanitra, Reiter, Simone F., Schuurs-Hoeijmakers, Janneke, Shieh, Perry B., Slavotinek, Anne, Smithson, Sarah, Stegmann, Alexander P. A., Tomczak, Kinga, Tveten, Kristian, Wang, Jun, Whitlock, Jordan H., Zweier, Christiane, McWalter, Kirsty, Juusola, Jane, Quintero-Rivera, Fabiola, Fischer, Utz, Yeo, Nan Cher, Kreienkamp, Hans-Jürgen, Lessel, Davor
Publicado 2021

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

por Teumer, Alexander, Tin, Adrienne, Sorice, Rossella, Gorski, Mathias, Yeo, Nan Cher, Chu, Audrey Y., Li, Man, Li, Yong, Mijatovic, Vladan, Ko, Yi-An, Taliun, Daniel, Luciani, Alessandro, Chen, Ming-Huei, Yang, Qiong, Foster, Meredith C., Olden, Matthias, Hiraki, Linda T., Tayo, Bamidele O., Fuchsberger, Christian, Dieffenbach, Aida Karina, Shuldiner, Alan R., Smith, Albert V., Zappa, Allison M., Lupo, Antonio, Kollerits, Barbara, Ponte, Belen, Stengel, Bénédicte, Krämer, Bernhard K., Paulweber, Bernhard, Mitchell, Braxton D., Hayward, Caroline, Helmer, Catherine, Meisinger, Christa, Gieger, Christian, Shaffer, Christian M., Müller, Christian, Langenberg, Claudia, Ackermann, Daniel, Siscovick, David, Boerwinkle, Eric, Kronenberg, Florian, Ehret, Georg B., Homuth, Georg, Waeber, Gerard, Navis, Gerjan, Gambaro, Giovanni, Malerba, Giovanni, Eiriksdottir, Gudny, Li, Guo, Wichmann, H. Erich, Grallert, Harald, Wallaschofski, Henri, Völzke, Henry, Brenner, Herrmann, Kramer, Holly, Leach, I. Mateo, Rudan, Igor, Hillege, Hans L., Beckmann, Jacques S., Lambert, Jean Charles, Luan, Jian'an, Zhao, Jing Hua, Chalmers, John, Coresh, Josef, Denny, Joshua C., Butterbach, Katja, Launer, Lenore J., Ferrucci, Luigi, Kedenko, Lyudmyla, Haun, Margot, Metzger, Marie, Woodward, Mark, Hoffman, Matthew J., Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Wareham, Nicholas J., Endlich, Nicole, Soranzo, Nicole, Polasek, Ozren, van der Harst, Pim, Pramstaller, Peter Paul, Vollenweider, Peter, Wild, Philipp S., Gansevoort, Ron T., Rettig, Rainer, Biffar, Reiner, Carroll, Robert J., Katz, Ronit, Loos, Ruth J.F., Hwang, Shih-Jen, Coassin, Stefan, Bergmann, Sven, Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Corre, Tanguy, Zeller, Tanja, Illig, Thomas, Aspelund, Thor, Tanaka, Toshiko, Lendeckel, Uwe, Völker, Uwe, Gudnason, Vilmundur, Chouraki, Vincent, Koenig, Wolfgang, Kutalik, Zoltan, O'Connell, Jeffrey R., Parsa, Afshin, Heid, Iris M., Paterson, Andrew D., de Boer, Ian H., Devuyst, Olivier, Lazar, Jozef, Endlich, Karlhans, Susztak, Katalin, Tremblay, Johanne, Hamet, Pavel, Jacob, Howard J., Böger, Carsten A., Fox, Caroline S., Pattaro, Cristian, Köttgen, Anna
Publicado 2016

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas

por Martin-Castillo, Begoña, Lopez-Bonet, Eugeni, Cuyàs, Elisabet, Viñas, Gemma, Pernas, Sonia, Dorca, Joan, Menendez, Javier A.
Publicado 2015

Genomic Classification of HER2-Positive Patients With 80-Gene and 70-Gene Signatures Identifies Diversity in Clinical Outcomes With HER2-Targeted Neoadjuvant Therapy

por Whitworth, Pat W., Beitsch, Peter D., Murray, Mary K., Richards, Paul D., Mislowsky, Angela, Dul, Carrie L., Pellicane, James V., Baron, Paul L., Rahman, Rakhshanda Layeequr, Lee, Laura A., Dupree, Beth B., Kelemen, Pond R., Ashikari, Andrew Y., Budway, Raye J., Lopez-Penalver, Cristina, Dooley, William, Wang, Shiyu, Dauer, Patricia, Menicucci, Andrea R., Yoder, Erin B., Finn, Christine, Blumencranz, Lisa E., Audeh, William
Publicado 2022

A nomogram for predicting the HER2 status of circulating tumor cells and survival analysis in HER2-negative breast cancer

por Yang, Yuqin, Li, Liudan, Tian, Wenjing, Qiao, Zhen, Qin, Qi, Su, Liqian, Li, Peiqiu, Chen, Weirong, Zhao, Hong
Publicado 2022

Molecular Features and Survival Outcomes of the Intrinsic Subtypes Within HER2-Positive Breast Cancer

por Prat, Aleix, Carey, Lisa A., Adamo, Barbara, Vidal, Maria, Tabernero, Josep, Cortés, Javier, Parker, Joel S., Perou, Charles M., Baselga, José
Publicado 2014

Socio-demographic characteristics and pre-hospital care of children with circulatory failure in a children’s emergency room in southern Nigeria

por Abiodun, Moses Temidayo, Sadoh, Wilson Ehidiamen
Publicado 2021

Context Sensitive Modeling of Cancer Drug Sensitivity

por Chen, Bo-Juen, Litvin, Oren, Ungar, Lyle, Pe’er, Dana
Publicado 2015

Chemotaxis in Escherichia coli: A Molecular Model for Robust Precise Adaptation

por Hansen, Clinton H, Endres, Robert G, Wingreen, Ned S
Publicado 2008